8. Epidemiology of peptic ulcer disease

Question 1

What percentage of the population is affected by peptic ulcer disease?

Answer 1

1-5%

Question 2

What are the risk factors associates with peptic ulcer disease?

Answer 2

Male
Smoker
Stress

Question 3

Explain the relationship between age and the prevalence of H. Pylori

Answer 3

% of those infected increases with age in the developed world but this may be due to knowledge available for better living conditions now than before
An 80 y/o woman has an 80% chance of being infected even at the age of 6

Question 4

In the West of Scotland, what is the relationship between socioeconomic status and the prevalence of H. Pylori?

Answer 4

The lower the socioeconomic status, the greater the prevalence of H. Pylori

Question 5

What is the prevalence of H. Pylori in:

a) healthy controls
b) gastric cancer
c) duodenal ulcers

Answer 5

a) 40%
b) approx 70%
c) 100%

Question 6

How common are gastric cancer deaths in relation to other cancers?

Answer 6

2nd commonest cause of cancer death worldwide

Question 7

What are the presenting complaints associated with gastric cancer?

Answer 7

Anaemia
Weight loss
Anorexia

Question 8

What % of the general population have H. Pylori?
What percentage of this has:
a) no disease
b) peptic ulcer disease
c) gastric cancer

Answer 8

Over 50%

a) >80%
b) 5-15%
c) 1-3%