8-12 Flashcards
CONSIDERED TO BE THE UNIVERSAL RBC DONORS
TYPE O
WHY IS TYPE O THE UNIVERSAL DNORS
due to the absence of A and B antigen on their Red cells
genes are autosomal codominant located on the short arm of what chromosome
chromosome 1
Rh antigens are inherited as
codominant alleles
Rh antigens are transmembrane polypeptides and are integral part of
RBC membrane
frequency of D
85 %
frequency of d
15%
frequency of c
80 %
frequency of C
70%
frequency of E
30 %
frequency of e
98%
DCE terminology is also known as
fisher-race
Rh-Hr terminology is also known as
weiner
Controlled by 3 closed linked loci
Rh inheritance
each locus has its own alleles which are
Dd,Cc,Ee
theory of multiple allelomorphoric gene
weiner
ALPHA/numeric terminology terminology is also known as
rosenfield
this system has no genetic basis
rosenfield
it simply demonstrate the presence or absence of the antigen in the red blood cell
rosenfield
minujs sign preceding a number designates
absence of antigen
numeric terminology
ISBT
UNIVERSAL LANGUAGE
ISBT
ADOPTED A ——– FOR EACH AUTHENTICATED BLOOD GRP SPECIFICITY
6-DIGIT
2ND 3 NUMBERS
ANTIGEN SPECIFICITY