8-12 Flashcards

1
Q

CONSIDERED TO BE THE UNIVERSAL RBC DONORS

A

TYPE O

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2
Q

WHY IS TYPE O THE UNIVERSAL DNORS

A

due to the absence of A and B antigen on their Red cells

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3
Q

genes are autosomal codominant located on the short arm of what chromosome

A

chromosome 1

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4
Q

Rh antigens are inherited as

A

codominant alleles

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5
Q

Rh antigens are transmembrane polypeptides and are integral part of

A

RBC membrane

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6
Q

frequency of D

A

85 %

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7
Q

frequency of d

A

15%

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8
Q

frequency of c

A

80 %

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9
Q

frequency of C

A

70%

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10
Q

frequency of E

A

30 %

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11
Q

frequency of e

A

98%

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12
Q

DCE terminology is also known as

A

fisher-race

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13
Q

Rh-Hr terminology is also known as

A

weiner

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14
Q

Controlled by 3 closed linked loci

A

Rh inheritance

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15
Q

each locus has its own alleles which are

A

Dd,Cc,Ee

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16
Q

theory of multiple allelomorphoric gene

A

weiner

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17
Q

ALPHA/numeric terminology terminology is also known as

A

rosenfield

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18
Q

this system has no genetic basis

A

rosenfield

19
Q

it simply demonstrate the presence or absence of the antigen in the red blood cell

A

rosenfield

20
Q

minujs sign preceding a number designates

A

absence of antigen

21
Q

numeric terminology

22
Q

UNIVERSAL LANGUAGE

23
Q

ADOPTED A ——– FOR EACH AUTHENTICATED BLOOD GRP SPECIFICITY

24
Q

2ND 3 NUMBERS

A

ANTIGEN SPECIFICITY

25
1ST 3 NUMBERS
SYSTEM
26
IgG in nature reacts at 37 degrees in AHG
rh antibodies
27
do not bind complement
rh antibodies
28
exposure to --------- of rh positive red cells can stimulate antibody production in an rh negative px
< 1 ml
29
refers to the presence or absence of the red cell D
Rh + , Rh -
30
most important red cell antigen in transfusion practice
D atigen
31
wht does D ANTIGEN has than other red cell antigen
greater immunogenicity
32
what isformed in transfusion and pregnancy
formation of anti-D
33
routine pre transfusion studies
only anti-D
34
other reagents
resolution of antibody problems or in family studies
35
methods used in experiment 9
slide method tube method
36
reagents used in exp 9
anti-D antiserum
37
sample used in experiment 9 for slide mtd
capillary blood
38
sample used in experiment 9 for tube mtd
2-5 % rcs
39
surface temperature
45-50 degrees celsius
40
mins in rh viewbox
5 mins
41
agglutination in the D tube combined with the smooth suspension in control tube red cell are
D +/ Rh +
42
result when there is a smooth suspension of red cells in both anti D and the control tube
negative
43
test performed to differentiate weak D expression from rh negative phenotype
antihuman globulin test (indirect)