7.5 Nerve Supply of the Limbs Flashcards
What makes up the central nervous system?
- Brain
- Spinal cord
- Retina and optic nerve (cranial nerve II)
What makes up the peripheral nervous system?
- Sensory pathways
- Motor pathways, which are:
- > Somatic nervous system
- > Autonomic nervous system (sympathetic, parasympathetic and enteric)
Made up of the cranial nerves and visceral autonomic nerves/ganglia/plexuses
How many pairs of symmetrically arranged spinal nerves are there?
31
Through where do the spinal nerves leave the spinal cord?
Through the intervertebral foramina of vertebrae
How many cervical nerves are there?
8 (C1-C8), but only 7 vertebrae (C1 exits spinal cord above C1 vertebrae, and C2 exits between C1 and C2 vertebrae)
How many thoracic nerves are there?
12 (T1-T12), associated with the 12 thoracic vertebrae
How many lumbar nerves are there?
5 (L1-L5), associated with the 5 lumbar vertebrae
How many sacral nerves are there?
5 (S1-S5), associated with the 5 fused sacral vertebrae
How many coccygeal nerves are there?
Only one, associated with the coccygeal vertebrae (varying numbers, frequently 4 fused vertebrae but ranges from 3-5)
How many nerves emerge from the brain?
There are 12 cranial nerves (CN I-XII)
Where does the spinal cord range from?
It is continuous with the brain stem above the foramen magnum, but extends from that point to around the level of the intervertebral disc between L1 and L2, tapering at an end point called the conus medullaris and becoming the cauda equina
What are the meninges?
The three layers of connective tissue that cover the spinal cord:
- Dura mater
- Arachnoid mater
- Pia matter
Where do thoracic, lumbar and sacral nerves emerge from the spinal cord?
From the intervertebral foramen of the respective vertebrae below them (equal numbers of nerves and vertebrae)
Where do cervical nerves emerge from the spinal cord?
From the intervertebral foramen of the respective vertebrae above them (8 cervical nerves, 7 vertebrae)
e.g. C8 emerges between C7 and T1
What is the foramen magnum?
Large hole in the skull that allows the passage of the brain stem/spinal cord, vertebral arteries/veins and the anterior/posterior spinal arteries/veins. Attached to the atlas via alar ligaments
Practise drawing out and labelling the spinal cord transverse diagram,
Do it!! Innervation of limbs lecture slide 6
What are the dorsal root ganglia (DRG)?
Swellings on the dorsal root of each nerve, contain the cell bodies of sensory nerves whose dendrites (in somatic nervous system) receive information from sensory receptors (these may be in skin, muscles or tendons)
Where do the axons of sensory nerves go to?
To the dorsal horn of the spinal cord
Describe the monosynaptic reflex arc.
- Sensory receptor detects change in environment/a stimulus
- This results in an impulse travelling up the dendrites, through the cell body and through the axons
- In the CNS, the sensory nerve has a synapse directly with a corresponding motor nerve (alternatively will synapse with a interneuron)
- Motor nerve leaves on the same segmental level and brings about a response to the stimulus
How can sensory and motor nerve information be transmitted within the CNS?
- Sensory information can travel up segmental levels to the brain if necessary, enter through the dorsal root (remember through dorsal
- Motor information can travel down the segmental levels from the brain until the necessary level is reached, emerging from ventral roots
Where can motor information be transmitted to from the spinal cord?
- The SNS (somatic nervous system), to voluntary striated muscle
- The ANS (autonomic nervous system), to cardiac muscle, glands and smooth muscle associated with viscera or blood vessels
Where do the cell bodies of motor neurons of the SNS lie?
In the ventral horn of the grey matter in the spinal cord
Where do the sensory nerves enter the spinal cord and from where do motor nerves leave?
Sensory nerves: enter through the dorsal root/rootlets
Motor nerves: emerge from the ventral root/rootlets
How is functional spinal segmentation indicated?
By the 31 PAIRS of symmetrical nerves emerging from the spinal column
Each pair refers to a ‘segment’ of the spinal cord
What forms the spinal nerves?
A union of the dorsal and ventral roots
- These are in turn formed of various dorsal and ventral rootlets
What emerges from the intervertebral foramen?
A mixed nerve, comprised of the joining of the dorsal and ventral roots
What structures do mixed nerves split into after emerging from the intervertebral foramen?
They split into posterior/dorsal and anterior/ventral rami, which can contain a mix of nerves
Which of the rami is larger, anterior or posterior?
- Anterior is a larger ramus
- Posterior is a smaller ramus
- Where do the thoracic rami innervate?
- Posterior/dorsal ramus supplies motor fibres of the back and sensation for the skin of the same region via a cutaneous branch
- Anterior/ventral ramus innervates muscles of the anterolateral thoracic wall, and sensation over the skin through a cutaneous branch
What are dermatomes?
Unilateral bands of skin/cutaneous regions that are provided with sensation by the same single spinal nerve
What are myotomes?
Unilateral portion of skeletal/striated muscle (can stretch over a large distance) that are all innervated or partly innervated by the same single spinal nerve
How can impingement of a nerve affect its dermatome and myotome?
- Pain may shoot down the nerve
- Regions may tingle or become numb
What do posterior/dorsal rami in the thoracic region innervate?
- Extensors of the spine
- Overlying skin
What do anterior/ventral rami in the thoracic region innervate?
- Limbs
- Ventral trunk
Do dermatomes overlap?
- Yes, adjacent dermatomes overlap fairly significantly, so transection of a single nerve is unlikely to lead to a massive/whole band where sensation is lost
- Difficulty in finding where dermatomes are (especially as they can vary from person to person) means that mapping dermatomes exactly in a diagram is extremely difficult, meaning ones in textbooks aren’t always 100% reliable
Do limb muscles receive innervation from a single spinal nerve/segment?
They can, but it is more likely for them to receive innervation from multiple segments/nerves (e.g. biceps brachii receives innervation from the C5, C6 and C7 spinal segmental levels via the musculocutaneous nerve, but majority of nerves come from the C5 segment so muscle ‘belongs’ to the C5 myotome, despite having regions that correspond to all 3)
What happens during limb development that affects dermatomes?
- Upper limb rotates laterally/dorsally so that flexors face anteriorly
- Lower limb rotates medially/ventrally so that extensors face anteriorly
This results in the twisting of dermatomes seen across the limbs
What does cutaneous mean?
Under/in the skin
What does loss of sensation or pain localised to a dermatome indicate?
Entrapment or damage to spinal nerves/spinal cord segments e.g. unilateral pain in dermatome S1 indicates the compression of the S1 spinal nerve, perhaps due to herniation of an intervertebral disc)
What is paraesthesia?
‘Pins and needles’, strange sensations occurring in a dermatome due to the brief compression or impingement of a peripheral nerve
How can compression of a peripheral nerve be indicated?
- Paraesthesia
- Pain localised to a limb peripheral nerve territory
What does loss of sensation below a specific dermatome indicate?
Damage to the spinal cord at that dermatomal level (e.g. bilateral loss of sensation below the T7 level dermatome indicates spinal cord trauma or pathology at that level
What does muscle weakness in a specific myotome indicate?
- A lesion at that spinal segment or to that spinal nerve
What myotome(s) controls shoulder abduction?
C5, e.g. deltoid (innervated by axillary nerve)
What myotome(s) controls shoulder adduction?
C6, C7, C8
What myotome(s) controls shoulder flexion?
C5
What myotome(s) controls shoulder extension?
C6, C7, C8