7.1 fluid mosaic model Flashcards
most of the membrane is
lipids and proteins
also carbohydrates are important
most abundant lipid in membrane
phospholipid
amphipathic molecule has
hydrophilic and hydrophobic end
fluid mosaic mode l
model of the membrane with-
- mosaic of proteins
- in phospholipids
Gorter and Grnedel
Dutch scientists that said that he membrane must be of phospholipid bilayers
Davson and Danielli
propose the sandwich model
phospholipid bilayer between 2 layers of proteins
2 problems of the sandwich model
1- generalized that all membranes are the same
2-proteins are also amphipathic
so if they are on the outside of the phospholidpid bilayer, the hydrophobic parts would touch water
Singer and Nicolson
propose that proteins are integrated in the the membrane with their hydrophilic parts sticking ut
(fluid mosaic model)
freeze fracturing
splits membrane along phospholidpids