7. Host-Pathogen Interactions

Question 1

Structure of the lecture

Answer 1

Understanding factors that drive the interactions between pathogens and their hosts

1. Host immunity
2. Environment
3. Pathogen class
4. Life history
5. Tissue specificity
6. Host specificity
7. Timing

Question 2

How can host immune system impact HPI?

1

Answer 2

1. Innate immune response
2. Adaptive immune response
3. Vaccination

Question 3

What environmental factors can drive HPI?

2

Answer 3

1. Host-factors
2. Pathogen factors

Question 4

How can different life-history traits drive HPI?

4

Answer 4

1. Location and entry to host
2. Replication within host
3. Timing
4. Specificity

Question 5

What two pathogens can we study to better understand host specificity?

5

Answer 5

1. T. gondii
2. S. enterica

Question 6

How can we better understand tissue specificity in HPI?

6

Answer 6

1. Niche formation
2. Different responses will be produced in different tissues
3. Studying S. enterica

Question 7

How can the timing of infection dictate HPI?

7

Answer 7

1. Time-critical responses
2. Eimeria spp. and dose-dependence