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Chemotherapy Viruses > 7 Facts of each virus > Flashcards

7 Facts of each virus Flashcards

1
Q

What is the memory hook for poliovirus?

A

The Flamingo Breeding Pool

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2
Q

What type of genetic information does poliovirus have?

A

ss RNA

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3
Q

What is the major dz of poliovirus?

A

Poliomyelitis

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4
Q

What is the transmission of Poliovirus?

A

Fecal-oral

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5
Q

Diagnosis of poliovirus

A

Sequencing by RT-PCR by the CDC

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6
Q

Pathogenesis of poliovirus

A

Viremia –> invasion of the CNS –> Lytic destruction of anterior horn cells

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7
Q

Vaccines for poliovirus

A

Live-attenuated oral/killed-virus injection

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8
Q

Anti-viral therapy for poliovirus

A

None

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9
Q

Consequences of poliovirus

A

Long lived protective immunity or paralysis

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10
Q

What is the memory hook for Coxsackie A virus?

A

Coxsackie Cockatoos

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11
Q

What type of gen. info does the Coxsackie virus have?

A

ssRNA

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12
Q

What dz is associated with Coxsackie virus?

A

Hand, Foot, and Mouth disease

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13
Q

What is the transmission for Coxsackie virus?

A

Fecal-Oral

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14
Q

Diagnosis of Coxsackie virus

A

Clinical dx or RT-PCR

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15
Q

Pathogenesis of Coxsackie virus

A

Viremia –> target skin –> cell death

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16
Q

Vaccines for Coxsackie virus

A

None

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17
Q

Anti-viral therapy for Coxsackie virus

A

None

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18
Q

Consequence of Coxsackie virus

A

Long-lived protective immunity

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19
Q

D68 memory hook

A

The Peak-Orna Animal Nursery

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20
Q

What type of gen. info does D68 have?

A

ssRNA

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21
Q

Dz of D68

A

Resp. Inf.

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22
Q

Transmission of D68

A

Resp. and contact with contaminated surfaces

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23
Q

Dx of D68

A

PCR and/or isolate virus and culture for cytopathic effect

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24
Q

Pathogenesis of D68

A

Viremia leading to resp. tract inf.

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25
Q

Vaccines for D68

A

NONE

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26
Q

Anti-viral’s for D68

A

Pleconaril (severe cases)

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27
Q

Consequences of D68

A

Long lived protective immunity

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28
Q

Hepatitis A virus memory hook

A

Hungry Hungry Hep A Hippos

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29
Q

What type of gen info does Hep A have?

A

ssRNA

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30
Q

Dz of Hep A

A

Hepatitis

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31
Q

Transmission of Hep A

A

Fecal-Oral

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32
Q

Dx of Hep A

A

IgM serology by antibody capture

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33
Q

Pathogenesis of Hep A

A

Viremia –> Target Liver

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34
Q

Vaccines for Hep A

A

Killed virus

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35
Q

Anti viral therapy for Hep A

A

Vaccine during prodrome period of infx

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36
Q

Consequence for Hep A

A

Long lived protective immunity

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37
Q

Rotavirus memory hook

A

A Race on the Rio

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38
Q

What type of gen info does Rotavirus have?

A

DS segmented RNA

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39
Q

Dz for Rotavirus

A

Diarrhea

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40
Q

Transmission for Rotavirus

A

Fecal-Oral

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41
Q

Pathogenesis for Rotavirus

A

Local replication, enterotoxin production

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42
Q

Vaccines for Rotavirus

A

Rotateq: live attenuated pentavalent vaccine
Rotarix: live attenuated vaccine against one genotype (more commonly given because fewer doses req.)

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43
Q

Anti viral therapy for Rotavirus

A

None

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44
Q

Consequence of Rotavirus

A

Short term immunity, less severe reinfx.

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45
Q

Norovirus memory hook

A

Cali Sea Cruise

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46
Q

What type of gen info does Norovirus have?

A

ssRNA

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47
Q

Dz of Norovirus

A

Diarrhea

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48
Q

Transmission of Norovirus

A

Fecal-oral

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49
Q

Dx of Norovirus

A

RT-PCR by film array

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50
Q

Pathogenesis of Norovirus

A

Lysis and shedding of epithelial cells

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51
Q

Vaccines for Norovirus

A

None

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52
Q

Anti-viral therapy for Norovirus

A

None

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53
Q

Consequences of Norovirus

A

Type specific immunity

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54
Q

Influenza virus memory hook

A

A Night shift at the Orthodontist’s

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55
Q

What type of gen info does Influenza virus have?

A

neg RNA segmented enveloped

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56
Q

Dz of Influenza virus

A

The Flu

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57
Q

Transmission of Influenza virus

A

Respiratory

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58
Q

Dx of Influenza virus

A

Film array by RT-PCR

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59
Q

Pathogenesis of Influenza virus

A

Local replication in resp. tract, necrosis of epithelial cells

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60
Q

Vaccines for Influenza virus

A

Live attenuated/killed virus

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61
Q

Anti-virals for Influenza virus

A

Amantadine or Neuraminidase inhibitors

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62
Q

Consequences of Influenza virus

A

Annual reinfection due to antigenic shift and and drift

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63
Q

Rhinovirus memory hook

A

Paranormal mixer

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64
Q

What type of gen info does Rhinovirus have?

A

pos RNA

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65
Q

Dz of Rhinovirus

A

Common cold

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66
Q

Transmission of Rhinovirus

A

Respiratory, fomites

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67
Q

Dx of Rhinovirus

A

Film array RT-PCR assay

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68
Q

Pathogenesis of Rhinovirus

A

Lytic replication in the resp. epithelium

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69
Q

Vaccines for Rhinovirus

A

None

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70
Q

Anti-viral therapy for Rhinovirus

A

None

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71
Q

Consequence of Rhinoviruses

A

Type Specific immunity

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72
Q

Respiratory Syncytial Virus memory hook

A

Paranormal mixer

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73
Q

What type of gen info does RSV have?

A

neg RNA enveloped

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74
Q

Dz of RSV

A

Severe lower resp. tract infx. in children

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75
Q

Transmission of RSV

A

Respiratory

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76
Q

Dx of RSV

A

Film array RT-PCR assay

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77
Q

Pathogenesis of RSV

A

Local replication in resp. tract, necrosis of epithelial cells

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78
Q

Vaccine for RSV

A

Preventative monoclonal abx, Palivizumab

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79
Q

Anti viral for RSV

A

None

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80
Q

Consequences of RSV

A

Short term immunity, less severe reinfection

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81
Q

Parainfluenza virus memory hook

A

Paranormal mixer

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82
Q

What type of gen info does Parainfluenza have?

A

neg RNA enveloped

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83
Q

Dz of Parainfluenza

A

Croup

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84
Q

Transmission fo Parainfluenza

A

Respiratory

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85
Q

Dx of Parainfluenza

A

Clinical dx or RT-PCR

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86
Q

Pathogenesis of Parainfluenza

A

Local replication in resp tract, necrosis of epithelial cells

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87
Q

Vaccines for Parainfluenza

A

None

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88
Q

Anti virals for Parainfluenza?

A

Glucocorticoids for severe cases of Croup

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89
Q

Consequences of Parainfluenza

A

Short term immunity

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90
Q

Mumps memory hook

A

Paranormal Mixer

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91
Q

What type of gen info does Mumps have?

A

neg RNA enveloped

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92
Q

Trans of Mumps

A

Resp (before Paratitis)

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93
Q

Dz of mumps

A

Mumps

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94
Q

Dx of Mumps

A

Clinical, confirmed by serology or sequencing performed by public health dept.

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95
Q

Pathogenesis of Mumps

A

Replication in resp. tract, viremia, targeting parotid gland

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96
Q

Vaccine for Mumps

A

Live-attenuated, MMR

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97
Q

Anti viral for Mumps

A

None

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98
Q

Consequences of Mumps

A

Long-term immunity

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99
Q

Measles memory hook

A

Paranormal mixer

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100
Q

What type of gen info does Measles have?

A

neg RNA enveloped

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101
Q

Trans for Measles

A

Respiratory

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102
Q

Dx of Measles

A

Clinical, confirmed by serology or sequencing performed by public health dept.

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103
Q

Pathogenesis of Measles

A

Replication in resp tract, viremia, rash

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104
Q

Dz of Measles

A

Measles

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105
Q

Vaccines for Measles

A

Live attenuated, MMR

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106
Q

Anti viral for Measles

A

None

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107
Q

Consequence of Measles

A

Long term immunity, SSPE

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108
Q

Rubella memory hook

A

Toga-toga-toga virus

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109
Q

What type of gen info does Rubella have?

A

reg RNA enveloped

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110
Q

Dz of Rubella

A

German measles

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111
Q

Transmission of Rubella

A
  • Respiratory

- Mother to Fetus

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112
Q

Dx of Rubella

A

Serology

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113
Q

Pathogenesis of Rubella

A

Replication in resp tract, viremia, rash

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114
Q

Vaccines for Rubella

A

Live attenuated MMR

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115
Q

Anti virals for Rubella

A

Long term immunity/Congenital Rubella syndrome

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116
Q

Parvovirus B19

A

Bombs Away

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117
Q

What type of gen info does Parvo virus B19 have?

A

ssDNA

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118
Q

Dz of Parvovirus B19

A

Erythema Infectiosums (Fifth disease)

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119
Q

Transmission of parvovirus B19

A

Resp

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120
Q

Dx of Parvovirus B19

A

Clinical dx/serology or PCR of serum from aplastic crisis

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121
Q

Pathogenesis of Parvovirus B19

A

Replicates in Erythroid precursor nuclei

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122
Q

Vaccines for Parvovirus B19

A

None

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123
Q

Anti virals for Parvovirus B19

A

IV Ig for aplastic crisis in immunocompromised patients

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124
Q

Consequence of Parvovirus B19

A

Long tem immunity

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125
Q

HIV memory hook

A

One Cane to Rule them all

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126
Q

What type of gen info does HIV have?

A

posRNA Lentivirus

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127
Q

Dz of HIV

A

Progress to AIDS

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128
Q

Trans of HIV

A

Mother to Child, transfusion, IV drug abuse, sexual

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129
Q

Dx of HIV

A

Serology and confirmation by western blot; RT-PCR for viral load in response to HAART; sequencing to look for drug resistance

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130
Q

Pathogenesis of HIV

A

Depletion of CD4 T cells

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131
Q

Vaccines for HIV

A

None

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132
Q

Antiviral therapy for HIV

A

HAART, multiple RT-inhibitors and protease inhibitors

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133
Q

Consequence of HIV

A

Susceptibility to opportunistic infx., progression to AIDS, death

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134
Q

Herpes Simplex Virus I memory hook

A

Herpes Hermes

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135
Q

What type of gen info does HSV I have?

A

DNA enveloped

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136
Q

Dz of HSV I

A

Cold sores/encephalitis

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137
Q

Trans of HSV I/II

A

Contact

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138
Q

Dx of HSV I/II

A

Clinical Dx, PCR the infected tissue, culture virus from lesion

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139
Q

Pathogenesis of HSV I

A

Replicates in epithelia, latent in trigeminal ganglia, reactivation

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140
Q

Vaccines for HSV I/II

A

None

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141
Q

Antivirals for HSV I/II

A

Acyclovir and Priteliver

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142
Q

Consequence of HSV I

A

Latent infx with recurrence

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143
Q

Dz of HSV II

A

Genital lesions, Neonatal Herpes

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144
Q

Pathogenesis of HSV II

A

Replicates in epithelia, latent in sacral ganglia, reactivation

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145
Q

Consequences of HSV II

A

Latent infx with recurrence, Neonatal death or neurological impairment or death

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146
Q

Varicella-Zoster Virus memory hook

A

Varicella Zeus-ter Virus

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147
Q

What type of gen info does VZV have?

A

DNA enveloped

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148
Q

Dz of VZV

A

Chicken pox/Shingles

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149
Q

Trans of VZV

A

Resp

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150
Q

Dx of VZV

A

Clinical Dx

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151
Q

Pathogenesis of VZV

A

Replicates in resp epithelium, viremia, rash, latent in dorsal root ganglia, reoccurrence as shingles is possible

152
Q

Vaccine for VZV

A

Acyclovir

153
Q

Consequence of VZV

A

Latent infx with reoccurrence as shingles

154
Q

Epstein-Barr Virus memory hook

A

Ye Old Epstein Bar

155
Q

What type of gen info does EBV have?

A

DNA enveloped

156
Q

Dz of EBV

A

Infectious mononucleosis

157
Q

Trans of EBV

A

Resp, Saliva

158
Q

Dx of EBV

A

Monospot (heterophile Ab) and/or serology for IgM to VCA

159
Q

Pathogenesis of EBV

A

Replicates and latent in B cells

160
Q

Vaccines for EBV

A

None

161
Q

Consequences of EBV

A

Latent infx with sporadic shedding, Burkitt’s Lymphoma, Nasopharyngeal carcinoma

162
Q

Anti virals for EBV

A

None

163
Q

Cytomegalovirus memory hook

A

Cyto “Mega-Lo” Virus

164
Q

What type of gen info does CMV have?

A

DNA enveloped

165
Q

Dz of Post transplant pneumonia, Neonatal CMV

A

Post transplant pneumonia, Neonatal CMV

166
Q

Trans of CMV

A

Contact/saliva/ secretions/mother to newborn

167
Q

Dx of CMV

A

PCR, Serology, Histology

168
Q

Pathogenesis of CMV

A

Infects epithelium, cell proliferation, latency in T cells, macrophages, and other cells
-sporadic shedding

169
Q

Vaccines for CMV

A

None

170
Q

Antivirals for CMV

A

Ganiciclovir or Letermovir

171
Q

Consequence of CMV

A

Latent infx. with life long shedding of virus, sequelae in neonates

172
Q

Human Herpes Virus 6 and 7 memory hook

A

The Roses of Roseola

173
Q

What type of gen info does HHV 6/7 have?

A

DNA enveloped

174
Q

Dz of HHV 6/7

A

Roseola/exanthem subitum

175
Q

Trans of HHV 6/7

A

Respiratory

176
Q

Dx of HHV 6/7

A

Clinical Dx

177
Q

Pathogenesis of HHV 6/7

A

Sudden onset of fever, fever resolves, THEN red rash appears, latency in T cells

178
Q

Vaccines for HHV 6/7

A

None

179
Q

Antivirals for HHV 6/7

A

None

180
Q

Consequences for HHV 6/7

A

Latent infx

181
Q

Human Herpes Virus 8 memory hook

A

Ring around a Kaposi

182
Q

What type of gen info does HHV 8 have?

A

DNA enveloped

183
Q

Dz of HHV 8

A

Kaposi’s sarcoma

184
Q

Trans of HHV 8

A

Sexual contact

185
Q

Dx of HHV 8

A

Clinical Dx / PCR

186
Q

Pathogenesis of HHV 8

A

T cells control infx, activation occurs during immunosuppression

187
Q

Vaccines for HHV 8

A

None

188
Q

Anti virals for HHV 8

A

None

189
Q

Consequences of HHV 8

A

Sarcoma lesions in AIDS patients unless treated with HAART

190
Q

Papilloma Virus memory hook

A

Papilloma Bugs

191
Q

What type of gen info does Papilloma have?

A

DNA

192
Q

Dz of Papilloma virus

A

warts, cervical carcinoma

193
Q

Trans of Papilloma virus

A

Contact

194
Q

Dx of Papilloma

A

Clinical Dx, Hybridization (Pap smear)

195
Q

Pathogenesis of Papilloma

A

Virus production associated with cell differentiation

196
Q

Vaccine for Papilloma

A

Virus like particle vaccine

197
Q

Antiviral for Papilloma

A

None

198
Q

Consequence of Papilloma

A

Type 16, 18, 31, 33 Cervical carcinoma

199
Q

Hepatitis B Virus memory hook

A

Hep B Love

200
Q

What type of gen info does Hep B have?

A

partial dsDNA enveloped

201
Q

Dz of Hep B

A

Hepatitis

202
Q

Trans of Hep B

A

Mother to Child, transfusion, IV drug abuse, sexual

203
Q

Dx of Hep B

A

Serology by antibody capture

204
Q

pathogenesis of Hep B

A

Viremia, targeting of the liver, persist in cells

205
Q

Vaccine of Hep B

A

Subunit vaccine

206
Q

Anti viral for Hep B

A

NRTIs

207
Q

Consequences of Hep B

A

Hepatocellular Carcinoma

208
Q

Hepatitis C virus memory hook

A

The Hep Sea

209
Q

What type of gen info does Hep C have?

A

pos RNA enveloped

210
Q

Dz of Hep C

A

Hepatitis

211
Q

Trans of Hep C

A

Transfusion, IV drug abuse, contact with blood

212
Q

Dx of Hep C

A

RT-PCR, sequencing for genotype, serology

213
Q

Vaccines for Hep C

A

None

214
Q

Pathogenesis for Hep C

A

Viremia, targeting of the liver, persistent infx

215
Q

Anti Virals for Hep C

A

Direct Acting anti-vitals (DAAs)

216
Q

Consequences of Hep C

A

Hepatocellular Carcinoma

217
Q

Hepatits Delta Virus memory hook

A

Hep B Love

218
Q

What type of gen info does Hep D have?

A

ssRNA viroid enveloped

219
Q

Dz of Hep D

A

Fulminant Hepatitis

220
Q

Trans of Hep D

A

Mother to Child, transfusion, IV drug abuse, sexual

221
Q

Dx of Hep D

A

Serology by antibody capture

222
Q

Pathogenesis of Hep D

A

Co-infx with HBV, viremia, targeting of the liver, fulminant dz

223
Q

Vaccine for Hep D

A

HBV subunit vaccine

224
Q

Antivirals for Hep D

A

NRTIs

225
Q

Consequences of Hep D

A

Chronic Hepatitis or Death

226
Q

What type of gen info does Hep E have?

A

pos RNA

227
Q

Dz of Hep E

A

Hepatitis (developing world)

228
Q

Trans of Hep E

A

Fecal-Oral

229
Q

Dx of Hep E

A

Serology or RT-PCR by the public health

230
Q

Pathogenesis of Hep E

A

Viremia, targeting of the Liver

231
Q

Vaccine for Hep E

A

None (in trials)

232
Q

Anti virals for Hep E

A

None

233
Q

Consequences for Hep E

A

Long-lived immunity; high mortality during pregnancy

234
Q

Yellow Fever virus memory hook

A

Flavor Packed Flavi

235
Q

What type of gen info does Yellow Fever virus have?

A

pos RNA enveloped

236
Q

Dz of Yellow Fever virus

A

Yellow Fever

237
Q

Trans of Yellow Fever

A

Mosquito bite (w/ urban cycle)

238
Q

Dx of Yellow Fever

A

Clinical Dx, confirmation by serology by public health department

239
Q

Pathogenesis of Yellow Fever

A

Viremia, extensive replication and cell death in liver

240
Q

Vaccine for Yellow Fever

A

Live-attenuated

241
Q

Anti-virals for Yellow Fever

A

None

242
Q

Consequences of Yellow Fever

A

Longterm immunity or death

243
Q

Dengue Virus memory hook

A

Flavor packed Flavi

244
Q

What type of gen info does Dengue virus have?

A

pos ss RNA

245
Q

Dz of Dengue virus

A

Hemorrhagic fever/break bone fever

246
Q

Trans of Dengue virus

A

Mosquito bite

247
Q

Dx of Dengue virus

A

RT-PCR , serology, or ELISA for NS1

248
Q

Pathogenesis of Dengue virus

A

Immunopathogenesis causing fever and rash

249
Q

Vaccine for Dengue virus

A

None

250
Q

Anti-viral’s for Dengue virus

A

None

251
Q

Consequence of Dengue virus

A

Antibody dependent enhancement of dz if infected with another serotype

252
Q

West Nile virus memory hook

A

Flavor packed Flavi

253
Q

What type of gen info does West Nile have?

A

pos ssRNA enveloped

254
Q

Dz of West Nile virus

A

Encephalitis, meningitis

255
Q

Trans of West Nile virus

A

Mosquito

256
Q

Dx of West Nile virus

A

RT-PCR and serology

257
Q

Pathogenesis of West Nile virus

A

Viremia, CNS infx

258
Q

Vaccine for West Nile virus

A

None

259
Q

Anti-viral’s for West Nile Virus

A

None

260
Q

Consequences of West Nile virus

A

Immunity or death (more neurologic disease in the yearly)

261
Q

St. Louis Encephalitis virus memory hook

A

Flavor packed Flavi

262
Q

What type of gen info does St. Louis Encephalitis virus have?

A

pos ssRNA enveloped

263
Q

Dz of St. Louis Encephalitis virus

A

Encephalitis

264
Q

Trans of St. Louis Encephalitis

A

Mosquito

265
Q

Dx of St. Louis Encephalitis

A

RT-PCR and serology

266
Q

Pathogenesis of St. Louis Encephalitis

A

Viremia, CNS infx

267
Q

Vaccine for St. Louis Encephalitis

A

None

268
Q

Anti virals for St. Louis Encephalitis

A

None

269
Q

Consequences of St. Louis Encephalitis

A

Long-term immunity or death (rare)

270
Q

Chikungunya virus memory hook

A

Toga-Toga-Togavirus

271
Q

What type of gen info does Chikungunya have?

A

pos ssRNA enveloped

272
Q

Dz of Chikungunya

A

Chikungunya fever, myalgia, arthralgias

273
Q

Trans of Chikungunya

A

Insect vector

274
Q

Dx of Chikungunya

A

Serology or RT-PCR by the public health

275
Q

Pathogenesis of Chikungunya

A

Viremia, polyarthralgia, rash

276
Q

Vaccine for Chikungunya

A

None

277
Q

Antivirals for Chikungunya

A

None

278
Q

Consequences of Chikungunya

A

Polyarthralgia can last weeks or months, recovery

279
Q

EEE, WEE, and VEE memory hook

A

Toga-Toga-Togavirus

280
Q

What type of gen info does EEE, WEE, VEE have?

A

pos RNA enveloped

281
Q

Dz of EEE, WEE, VEE

A

Encephalitis

282
Q

Trans of EEE, WEE, VEE

A

Mosquito

283
Q

Dx of EEE, WEE, VEE

A

Serology or RT-PCR by public health dept.

284
Q

Pathogenesis of EEE, WEE, VEE

A

Viremia, CNS infx

285
Q

Vaccine for EEE, WEE, VEE

A

For Horses only

286
Q

Anti virals for EEE, WEE, VEE

A

None

287
Q

Consequences of EEE, WEE, VEE

A

Long term immunity or death

288
Q

California Encephalitis virus memory hook

A

Paul Bunyavirus

289
Q

What type of gen info does California Encephalitis virus have?

A

pos/neg segmented RNA enveloped

290
Q

Dz of California Encephalitis virus

A

Encephalitis

291
Q

Trans of California Encephalitis virus

A

Mosquito

292
Q

Dx of California Encephalitis virus

A

Serology

293
Q

Pathogenesis of California Encephalitis virus

A

Viremia, CNS infx

294
Q

Vaccine for California Encephalitis virus

A

None

295
Q

Anti virals for California Encephalitis virus

A

None

296
Q

Consequence of California Encephalitis virus

A

Long term immunity

297
Q

Colorado Tick Fever virus memory hook

A

A Race on the Rio (Grande Prix)

298
Q

What type of gen info does Colorado Tick Fever have?

A

DS segmented RNA

299
Q

Dz of Colorado Tick Fever

A

Fever and rash

300
Q

Trans of Colorado Tick Fever

A

Tick bite

301
Q

Dx of Colorado Tick Fever

A

Serology by the public health dept.

302
Q

Pathogenesis of Colorado Tick Fever

A

Viremia, inflammation, and rash, recovery

303
Q

Vaccine for Colorado Tick Fever

A

None

304
Q

Anti viral for Colorado Tick Fever

A

None

305
Q

Consequences of Colorado Tick Fever

A

Long-term immunity

306
Q

Hantavirus memory hook

A

Paul Bunyavirus

307
Q

What type of gen info does Hantavirus have?

A

pos/neg segmented RNA enveloped

308
Q

Dz of Hantavirus

A

Pulm syn.

309
Q

Trans of Hantavirus

A

Inhalation of secretions from infected animal

310
Q

Dx of hantavirus

A

Serology by public health dept.

311
Q

Pathogenesis of Hantavirus

A

Viral replication in resp. tract, inflammation, pneumonia

312
Q

Vaccine for Hantavirus

A

None

313
Q

Antiviral for Hantavirus

A

None

314
Q

Consequences of Hantavirus

A

Long term immunity and latency

315
Q

Ebola virus memory hook

A

Soccer Field’o virus

316
Q

What type of gen info does Ebola virus have?

A

neg RNA enveloped

317
Q

Dz of Ebola virus

A

Hemorrhagic fever

318
Q

Trans of Ebola virus

A

Direct contact with blood or body fluids

319
Q

Dx of Ebola Virus

A

RT-PCR from sera

320
Q

Pathogenesis of Ebola Virus

A

Viremia, replication in all cells, cell death, organ failure

321
Q

Vaccine for Ebola virus

A

None

322
Q

Antivirals for Ebola virus

A

Supportive care, non-FDA approved specific antibodies

323
Q

Consequences of Ebola Virus

A

Long term immunity, persistent infx, or DEATH

324
Q

Coronavirus memory hook

A

Kingdom of Sars

325
Q

What type of gen info does Coronavirus have?

A

pos ssRNA

326
Q

Dz of Coronavirus

A

Common cold, gastroenteritis, SARS, MERS

327
Q

Trans of Coronavirus

A

Resp, fecal-oral

328
Q

Dx of Coronavirus

A

Film array PCR

329
Q

Pathogenesis of Coronavirus

A

Local Replication and cell death

330
Q

Vaccine for Coronavirus

A

None

331
Q

Antivirals for Coronavirus

A

None

332
Q

Consequences of Coronavirus

A

pandemic potential of emerging viruses like SARS and MERS, type specific immunity

333
Q

Adenovirus memory hook

A

A Den-O Lions

334
Q

What type of gen info does Adenovirus have?

A

DNA

335
Q

Dz of Adenovirus

A

Multiple UR syndromes, conjunctivitis

336
Q

Trans of Adenovirus

A

Respiratory

337
Q

Dx of Adenovirus

A

Film array PCR

338
Q

Pathogenesis of Adenovirus

A

Replication in epithelial class, viremia ???

339
Q

Vaccine for Adenovirus

A

Live-attenuated (military only)

340
Q

Consequence of Adenovirus

A

Long term immunity

341
Q

Smallpox memory hook

A

Pox in a Box

342
Q

What type of gen info does Smallpox have?

A

DNA enveloped

343
Q

Dz of Smallpox

A

Smallpox

344
Q

Trans of Smallpox

A

Resp.

345
Q

Dx of Smallpox

A

CDC would sequence the virus and follow up on contacts

346
Q

Pathogenesis of Smallpox

A

Viremia and rash

347
Q

Vaccine for Smallpox

A

Live-attenuated

348
Q

Antivirals for Smallpox

A

None

349
Q

Consequence of Smallpox

A

Eradicated! Candidate vaccine vector

350
Q

Rabies virus memory hook

A

Rabid wrecking yard

351
Q

What type of gen info does Rabies virus have?

A

neg ssRNA enveloped

352
Q

Dz of Rabies

A

Rabies

353
Q

Trans of Rabies

A

Bite or contact with secretions of raccoon, skunk, or bat

354
Q

Dx of Rabies

A

Detection of viral antigens in the brain; RT-PCR for genotype

355
Q

Pathogenesis of Rabies

A

Replication in muscle, spread from nerves to brain

356
Q

Vaccine for Rabies

A

Killed virus

357
Q

Anti virals for Rabies

A

Anti-rabies Ig post exposure, no effective therapy after onset of CNS sx

358
Q

Consequences of Rabies

A

Immunity or death

359
Q

Molluscum Contagious memory hook

A

Pox in a Box

360
Q

What type of gen info does Molluscum Contagious have?

A

DNA enveloped

361
Q

Dz of Molluscum Contagiosum

A

Molluscum Contagious

362
Q

Trans of Molluscum Contagious

A

Contact

363
Q

Dx of Molluscum Contagious

A

Clinical dx from pearl like lesions

364
Q

Pathogenesis of Molluscum Contagious

A

Painless lesions that take months to resolve

365
Q

Vaccine for Molluscum Contagious

A

None

366
Q

Anti virals for Molluscum Contagious

A

None

367
Q

Consequences of Molluscum Contagious

A

Long term immunity, persistent in AIDS patients

368
Q

Zika Virus memory hook

A

Flavor Packed Flavi

369
Q

What type of gen info does Zika Virus have?

A

pos RNA enveloped

370
Q

Dz of Zika Virus

A

Fever, rash in 20% of pplz infection; microcephaly (in babies of pregnant mothers infected with the virus)

371
Q

Trans of Zika Virus

A

Sexual contact (semen); mosquito (aides egypti)

372
Q

Dx of Zika Virus

A

RT-PCR and serology done by CDC or public health dept.

373
Q

Pathogenesis of Zika Virus

A

Fever, rash and viremia in mom, microcephaly in babies

374
Q

Vaccines for Zika Virus

A

None (17D based vaccines in development)

375
Q

Antivirals for Zika Virus

A

None

376
Q

Consequences of Zika Virus

A

once a person is infected, he or she is likely to be protected from future infections

Chemotherapy Viruses (5 decks)

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