6th Year Exam Flashcards
Antibiotics in mononucleosis
Amoxicillin can cause rash
Cephalosporin will not give rash
10 poisons in childhood
1) acetaminophen
2) salicylate
3) oral hypoglycemics
4) anticholinergics
5) organophosphates
6) caustic ingestion (acid/alkali)
7) opioids
8) acute iron poisoning
9) lead poisoning
10) ethanol
Examples of AD inheritance
Achondroplasia, Ehler-Danlos, Marfan, MEN syndromes, NF1 and2, osteogenesis imperfecta, vWf deficiency
Examples of AR inheritance
AR polycystic kidney diseases, CF, galactosemia, hereditary hyperbilirubinemias, maple syrup urine disease, phenylketonuria, some primary immunodeficiencies,
Examples of XR inheritance
G6PD deficiency, Bruton agammaglobulinemia, Hemophilia A and B, Duchenne and Becker
Examples of XD inheritance
Fragile X syndrome, Alport syndrome, x-linked hypophosphatemic rickets
Short stature calculation
Mid-parental height = (fathers height + mothers +/- 13cm)/2
+boys/-girls
Quick about changes in circulation at birth
Dec. pulmonary resistance -> inc pressure L atrium -> Foramen ovale close -> inc O2 from resp and dec in PGs from placental separation -> closure of ductus arteriosus
Synonym for congenital hypoplastic anemia
Diamond blackfan anemia
Viruses connected to aplastic anemia
Parvovirus B19, HIV, hepatitis, EBV, CMV
Primary amenorrhea - ovarian issues
- Turner syndrome (streak gonads)
- Aromatase def. (lack hormone to convert androgen to estrogen)
- Chemo/radiation (ovarian failure)
Primary amenorrhea - hypothalamus/pituitary issues
- Kallmann syndrome (Failure of GnRH-producing cells to develop, also anosmia)
- Tumor (compression/infiltration of pituitary)
- Malnutrition (leads to hypothalamic dysregulation, inhibits GnRH)
Causes of primary testicular failure
Klinefelter (XXY), cryptorchidism, mumps orchitis, injury, chemo/radiation
Causes of secondary testicular failure
Pituitary disorders, inflammatory diseases, Kallmann syndrome, drugs, obesity
Intestinal atresia
Failure of a hollow viscus organ to develop appropriately. Can be stenosis, absence or rotation of a portion of the intestine
Sign duodenal atresia
Double bubble sign on x-ray (also seen in malrotation with volvulus)