6A/6B Flashcards
What is a hormone?
Chemical produced by gland transported by circulatory system through the body.
3 functional hormone classes, define each:
Homeostatic= maintains internal metabolic balance and regulates physiological systems in an organism. Gonadal= control reproductive function, bestow sexual appearance, and identify as male or female. Glucocorticoid= secreted in time of stress. Important in protein and carb metabolism.
Gonadal hormone that instructs body to develop as a male? / Female?
Testosterone = male Estrogen = female
Anabolic androgenic meanings?
What is it?
Negative effects?
Anabolic means muscle building, androgenic mascanolizes.
Synthesized testosterone.
Reduces fertility, roid rage, tumors and heart attack.
Tolerance:
Less effective, need more to feel buzz/effect.
Sensitization:
Response to stimulus strengthens like first use of cocaine
Wanting and Liking Theory:
Wanting = craving (increases after time) Liking = pleasure (decreases after time)
Differences in drug affect?
fat people need more of drug, because a lot of space.
Old people and babies need less because weak BBB.
Substance abuse:
Relies chronically and excessively.
Substance dependence:
More than abuse but includes abuse. Can’t maintain job, be a mother, addiction. Associated with tolerance and withdrawal.
Withdrawal:
Unpleasant physical and psychological symptoms when drug is ceased.
What pathway is acted on by abused drugs? In liking and wanting theory?
Dopamine increased by drugs. Mesolimbic dopaminergic pathway is acted upon.
Agonist:
Example:
Increases neurotransmission.
Example: block Reuptake so more serotonin. Block enzymes from breaking down.
Antagonist:
Example:
Decreases NT.
Block receptors, increase enzymes
What happens with Alcohol in the body in regards to antagonist and agonist?
Antagonist with glutamine, agonist gaba.