Drug reactions Flashcards

1
Q

Treatment for toxicity : Acetaminophen

A

N-acetylcysteine which replenishes glutathione

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2
Q

Treatment for toxicity : AChE inhibitors, organophosphates

A

atropine>pralidoxime

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3
Q

Treatment for toxicity : antimuscarinic, anticholinergic agents

A

physostigmine to control hyperthermia

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4
Q

Treatment for toxicity : arsenic

A

Dimercaprol,succimer

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5
Q

Treatment for toxicity : benzodiazepines

A

flumazenil

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6
Q

Treatment for toxicity : beta blockers

A

atropine

glucagon

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7
Q

Treatment for toxicity : carbon monoxide

A

100% oxygen

hyperbaric O2

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8
Q

Treatment for toxicity :copper

A

penicillamine

trientine (copper penny)

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9
Q

Treatment for toxicity :cyanide

A

Nitrate +thiosulfate,hydroxocobalamin

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10
Q

Treatment for toxicity : digoxin/digitalis

A

anti-dig fab fragments

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11
Q

Treatment for toxicity :heparin

A

protamine sulfate

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12
Q

Treatment for toxicity : Iron

A

Deferoxamine
deferasirox
deferiprone

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13
Q

Treatment for toxicity : mercury

A

diMERcaprol

succiMER

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14
Q

Treatment for toxicity : methanol, ethylene glycol (antifreeze)

A

fomepizole>ethanol, dialysis

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15
Q

Treatment for toxicity : methemoglobin

A
methylene blue
vitamin C (reducing agent)
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16
Q

Treatment for toxicity : opiods

A

naloxone

17
Q

Treatment for toxicity : salicylates

A

NaHCO3 (alkalinize urine), dialysis

18
Q

Treatment for toxicity : TCAs

A

NaHCO3 (stabilizes cardiac cell membrane)

19
Q

Treatment for toxicity :warfarin

A
vitamin K (Delayed effect)
Fresh frozen plasma (immediate)