6.3.3 Non-Coding DNA and Regulatory Genes Flashcards

1
Q

Why is it difficult to translate the genome of complex organisms?

A

It can be highly difficult to translate the genome of complex organisms into their proteome

Determining the proteome of humans is difficult as large amounts of non-coding DNA are present in human genomes

It can be very hard to identify these sections of DNA from the coding DNA

The presence of regulatory genes and the process of alternative splicing in human genomes also affects gene expression and the synthesis of proteins

The proteome is larger than the genome due to:

Alternative splicing

Post-translational modification of proteins (often takes place in the Golgi apparatus)

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