6.2- Patterns of inheritance Flashcards
Describe phenotype
- the appearance of an organism
- influenced by both genotype and environment
Name Genetic factors that cause phenotypic variation
1) Gene Mutations
2) Chromosome mutations
3) Sexual reproduction
What us he name of agents that increase rate of mutation, name different categories
Mutagens:
- physical agents
- chemical agents
- biological agents
List physical agents (mutagens)
- X-rays
- Gamma rays
- UV light
List chemical agents (mutagens)
- Benzopyrene (found in tobacco smoke)
- Mustard gas
- Nitrous oxide
- aromatic amines (in some synthetic dyes)
- Reactive oxygen species- free radicals
- Colchicine
List biological agents (mutagens)
Biological agents
* Some viruses
* Transposons- jumping genes, remnants of viral nucleus acid that have become incorporated into our genomes
* Food contaminants such as mycotoxins from fungi, e.g. aflatoxins in contaminated nuts, chemicals in charred meat,, alcohol
Describe the effects of gene mutations
Can be harmful, advantageous, or neutral
Describe the characteristics of mutations that occur during gamete formation
- Persistent- can be transmitted through many generations without change
- Random- not directed by a need on the part of the organism in which they occur
When do chromosome mutations occur, name different types
Occur during meiosis. Include:
* Deletion
* Inversion
* Translocation
* Duplication
* Non-disjunction
* Aneuploidy
* Polyploidy
Outline deletion (chromosome mutation)
Part of a chromosome, containing genes and regulatory sequences, is lost
Outline inversion (chromosome mutation)
- A section of a chromosome may break off, turn through 180 degrees, and then join again
- Although all the genes are still present, some may now be too far way from their regulatory nucleotide (control site) to be properly expressed
Outline translocation (chromosome mutation)
- A piece of one chromosome breaks off and then becomes attached to another chromosome
- May also interfere with regulation of genes on the translocated chromosome
Outline duplication (chromosome mutation)
- a piece of a chromosome may be duplicated
- Overexpression of genes can be harmful, because too many of certain proteins or gene-regulating nucleic acids may disrupt metabolism
Outline Non-disjunction (chromosome mutation)
- One pair of chromosomes or chromatids fails to separate, leaving one gamete with an extra chromosome
- When fertilised by a normal haploid gamete, the resulting zygote has one extra chromosome- e.g. Down syndrome (Trisomy 21) is caused by non-disjunction
Outline aneuploidy (chromosome mutation)
- The chromosome number is not an exact number if the haploid number for that organism
- Sometimes chromosomes or chromatids fail to separate during meiosis (e.g. trisomy)
Outline polyploidy (chromosome mutation)
- If a diploid gamete is fertilised by a haploid gamete, the resulting zygote will be triploid (has 3 sets of chromosomes)
- The fusion of 2 diploid games can male a tetraploid zygote
- Doesn’t occur in animals
- Many cultivated plants are polyploid (they have more than 2 sets of chromosomes)
Describe how genetic variation occurs in sexual reproduction
Has contributed to evolution:
- allele shuffling during crossing over in P1
- independent assortment of chromosomes in M/A1
- independent assortment of chromatids in M/A2
- random fusion of genetically dissimilar haploid gametes (only contain one of each our of homologous chromosomes and one allele for every gene)
Describe examples of variation caused only by the environment
- Speaking regional dialect- offspring don’t inherit, but learnt by listening to others
- Losing a limb or scarring following injury
Describe an example of Variation caused by environment interacting with genes in plants
- If plants are kept in dim light after germination, or if the soil in which they are grown contains insufficient magnesium, then the leaves do not develop enough chlorophyll and are yellow or yellow-white
- The plant is described as chlorotic, or suffering from chlorosis
- The plant cannot photosynthesise
- Chlorotic plants have the genotype for making chlorophyll, but environmental factors are preventing the expression of these genes
Nam different causes of variation
- genetic
- environmental
- combination of the two
Briefly outline the history of artificial selection
- humans have been practicing animal and plant breeding via AS for around 10,000 years- since beginning of settled agriculture
What is the agent of selection in natural vs artificial selection
- natural- environment
- artificial- humans
Outline the process of artificial selection
- breeders select individuals with the desired traits and allow them to interbreed
- at the same time, they prevent those without the the desired characteristics from breeding
name examples of species humans have domesticated
- cereals
- potatoes
- vegetables and fruits
- cattle
- pigs
- sheep
- goats
- horses
- oxen
- dogs
- cats
- pigeons
- poultry