6.2 Digestion and Absorption Flashcards
HCL function in the stomach
Gastric pits release HCL
1. provides an acidic medium that cancels the effect of saliva, thus maintaining a pH value below 7
2. kills bacteria present in food
3. HCL converts the inactive enzyme of pepsinogen into the active form of pepsin (breaks down proteins and turns them into amino acids).
4. denature proteins
Know that protein digestion begins in stomach
mechanical digestion (physically breakdown food), Food entering stomach causes distention (stretch receptors release enzymes causing chem digestion), produce chyme (semi fluid mass of partially digested food)
most chemical digestion begins in small intestine
hydrolysis (enzymes)-macromolecules hydrolyzed into smaller molecules. Gives different chemical composition through enzyme-catalyzed reactions
hormonal and nervous mechanisms that control secretion, content and volume of gastric juices
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role of pancreas in digestion
the pancreas produces a variety of enzymes that breakdown major good groups and secreted thru duct into lumen of SI
secretin stimulates pancreas
Enzymes
Amylase, Lipase, Trypsin, and Nuclease all produced in increased and activated in lumen of SI. all slightly alkaline
diff methods of membrane transport required to absorb different nutrients
- Diffusion - fatty acids and other non polar substances easily pass through hydrophobic cell membranes of epithelial cells through simple diffusion
- Osmosis - water diffuses across epithelial cells membranes in response to the movement of ions and other hydrophilic monomers
- Active transport - glucose and aa pumped againsts conc. gradient or transported with NA ions bc actively pumped against conc gradient
role of large intestine
main function-absorption of water
–secretes mucus
–movement of undigested / food products
–egestion (materials not absorbed) BELCH
–cellulose and lignin (not digested bc humans do not posses enzymes or gut bacteria to break them down break down alpha not beta
role of fiber in diet
more fiber=faster role of transit=less exposure to undesirable food=chemicals decrease contact time btwn intestinal wall and food
fiber does…
-clean out old damaged intestinal cells and unabsorbed materials
-provide bulk to keep materials moving
-absorb water to keep feces soft
-decrease hunger
-“works out” bodies bacteria
-reduce constipation
-lowers risk of colon cancer
-lower blood cholesterol
ULCERS (Helicobacter Pylori)
ulcers-inflamed damaged areas of open sores in stomach
causes and consequences of PKU
genetically inhereted disease caused by the inability to metabolize amino acid phenylene to tyrosine
phenalylinye builds up in tissue and blood due to lack of enzyme that breaks down phenylene from inheriting mutated form of a gene
treatment– lowp rotein in diet to limit intake of protein sources that contatin phenylene and supplement with formual containing essential AAs