6.1.12 manage px sx rd Flashcards
What does the vitreous look like in a normal young eye?
A homogenous solid gel that appears optically empty
Where in the eye is the vitreous gel bag most tightly adhered to the retina?
- ora serrata
- blood vessels
- optic disc
- in myopic px, areas of lattice
How does the ora serrata relate to the vitreous bag?
boundary between retina and ciliary body- this is where the vitreous base is and it is anchored throughout life even after pvd even though rest of vitreous bag has shrunk into the centre of the eye
Average age for PVD?
50-70 yrs
Which px are rd’s more likely?
- myopes
- trauma
- after ocular surgery
- ocular inflammation
What is the relationship between PVD and rhegmatogenous rd (rrd)?
PVD begins- vitreous liquefaction/syneresis
- vitreous contracts separating from retina
- Any hole in the vitreous bag lets liquefied vitreous enter the space between the retina and contracting vitreous gel- this liquiefied vitreous causes vitreous gel to pull away further from the retina and sink inferiorly. Any weak attachment between the vitreous bag and retina then it will pull away completely.
- Photopsia sx may occur in areas where the vitreous is still attached to the retina as the tugging continues and pulls at the retina
- Collagen filaments/fibres left in the vitreous bag aggregate together and float in vitreous (floaters)
Retinal tear
- During vitreous collapse, a shearing force is exerted in areas where there is a strong adhesionto the retina which may cause a retinal tear and if it is over a blood vessel a vitreoous haemorrhage may occur
- Tears associated with a PVD are commonly superior, symptomatic and U-shaped. As the vitreous bag contracts, the bag pulls into the centre and drops inferiorly
Retinal detachment
- A rhegmatogenous retinal detachment (RRD) results from fluid entering the space between the RPE and neuro-sensory retina through a hole or tear (subretinal space)
- Most RRDs begin superiorly, usually superior temporally
- Due to gravitational forces, RRDs may progress quickly to involve the macula
What are the 3 types of RD?
- Rhegmatogenous
- Exudative
- Tractional
How does an exudative rd occur?
Fluid from choroid gets into subretinal space through damaged RPE or blood-retinal barrier
- common causes include a sub-retinal neovascular membrane (AMD) or choroidal malignant melanoma
How does a tractional rd occur?
Sensory retina is pulled away by contracting proliferative membranes
e.g. new vessels in diabetic retinopathy grow out from the retina, into vitreous. They are usually very weak but form a scaffold and so if vitreous contracts or there is a shearing force again- it tuges on fine new vessels causing bleeding and can also lift off the retina . With eye movement or a PVD, blood vessels pulled towards centre of the eye taking retina with it
What is the risk of an rd in normal eyes compared to highly myopic eyes?
normal is 1 in 300
in highly myopic eyes (>6D) this increases to 1 in 20
What is the common timescale of RD after PVD?
Most RDs occur within 6 weeks of PVD
An RD after 3 months of PVD onset is rare
What causes vitreous floaters?
Vitreous liquefication from vitreous syneresis where collagen aggregates in the contracting vitreous bag and floats around
What do vitreous floaters look like?
Are entopic images of opacities most visible when seen against a uniform, bright background, they move on eye movement.
Awareness depends on:
-size
-optical density of the opacity
-distance from retinal surface
-pupil size
The closer an opacity to the retina, the larger the apparent shadow
Opacities are more noticeable with a dilated pupil
What are the causes for floaters (and why) in order of most clinical concern to least?
- Blood, pigment or inflammatory cells in the vitreous: from RD, posterior uveitis or vitreous haemorrhage
- Vitreous floaters: age-related from vitreous liquefaction culminating in PVD
- Asteroid Hyalosis: calcium soaps attached to collagen fibres- generally in older px and 90% cases unilateral
- Debris in the tear film: move with eye blink more than vitreous floaters
- Corpuscles in retinal blood vessels: tiny, rapidly moving specks visible when staring at a bright uniform surface
What does photopsia look like?
Luminous flashes associated with PVD, tears or RRD usually have a vertical orientation and are exacerbated by rapid eye movement
What are the causes of photopsia?
RD: rhegmatogenous, exudative, tractional
Acute PVD: Vitreous contraction associated with PVD pulls on retina causing stimulation of photoreceptors- once a PVD is complete (vitreous bag only attached at ora serrata) the traction on the retina is released and photopsia will cease
Migraine with visual aura: Definite pattern, associated headaches common, px past hx
Retinal disease: such as artery occlusion or multiple evanescent white-dot syndrome- look for associated retinal signs
How may a px present with an RD?
60% of px with RD have sx of floaters with or without flashes.
The remainder of px with RD have no sx until a black shadow or curtain enters their field of vision
What px Hx is important and why in those presenting with f+f?
Age: PVD is age-related occurring in <10% of people aged under 50yrs, but in >60% of people aged over 65yrs
Myopia: Myopes are 5x more likely to have retinal degenerations e.g. lattice, which pre-dispose to rd
Family hx or previous RD: Increased risk of RD if family Hx or RD in the fellow eye
Systemic disease: Proliferative diabetic retinopathy can cause tractional retinal detachments
Hx of ocular trauma, surgery or inflammation: cataract operations increase risk of RRD. 50% of RRDs occur within 1 year of cataract operation. Inflammation can cause premature PVD
Loss or distortion of vision: (usually a late sx) Px describe curtains, shadows, veils across vision- suggests RD or vitreous haemorrhage. Metamorphopsia may be reported
How do you investigate sx of floaters and how concerning are the answers?
- Are floaters of recent onset or always been there? If stable less concerning than recent or changing
- What do they look like? Vitreous degeneration with or without a corresponding RD usually described as a few small dots, lines, twigs, hairs or cobwebs. Vitreous floaters move on eye movement
- How many floaters are there? Too many to count and/or sudden shower/cloud is ominous: Suggests blood/pigment cells present due to tear or RD NB: look for signs
- Which eye do you see them in? Localisation usually helpful to differentiate which eye affected -RD essentially unilateral