Where are most alpha-2 receptors located?

In the central nervous system (Raul with the 2 candles in the water next to the brain)

What is an analog of clonidine that is used in pregnancy?

Alpha-methyldopa (the alpha dope rope above Christine's head)

What is the mechanism of action of tizanidine?

Alpha-2 agonist; centrally acting muscle relaxant (think of the letter to X-tine on the relaxing chair)

Phentolamine is a ____________.

reversible alpha-1 and -2 antagonist (the phantom appears and disappears, extinguishing the candles)

What kind of drug is phenoxybenzamine?

Irreversible alpha antagonist (the phantom has an irreversible tattoo of a phoenix)

Phentolamine is used to treat ___________ overdoses.

cocaine (guy with hot cocoa being scared by the phantom) because you don't want to use beta-blockers; also tyramine toxicity (the aged wine and cheese), because tyramine inhibits MAO

The increase in blood pressure when standing is mediated by ___________.

alpha-1 receptors, so inhibiting these with an antagonist can produce orthostatic hypotension

Prazosin can also treat ___________.

PTSD (think of the praying man on the alpha-antagonist stage with the dog tags)

List the classification and mnemonic for mirtazapine.

Alpha-2 antagonist and serotonin effect enhancer (two drama faces – mirth and misery – above a double extinguished candle)

Alpha-methyl dopa can cause a _____________.

lupus-like syndrome (think of the wolf next to pregnant Christine beneath the alpha dope rope)

Sketchy Pharm: Alpha Drugs Flashcards by Billy Tran

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Sketchy Pharm: Alpha Drugs Flashcards

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