601 midterm Flashcards
Changes found in the airway of older persons
-Upper airway nasal passages less cartilaginous reducing patency
-Proximal and distal airways become less cartilaginous resulting in airtrapping
-increased soluble and cellular inflammation
-alveoli increase in size and decrease in elasticity
-increased apoptosis and senescence markers
-skeletal muscle atropies and diaphragm weakens leading to inadequate ventilation
when does the respiratory system decline and by how much per year
age 40, 35-50ml/year
most common pulmonary related symptoms in older adults
-rhinitis
-dyspnea
-cough
-wheezing and chest tightness
chronic rhinosinusitis symptoms
-longer than 12 weeks
-nasal discharge
-nasal congestion or obstruction
-facial pain or pressure
-loss of smell
(2+ is diagnostic)
risk factor for chronic rhinosinusitis
-increasing age
-smoking
older adults with chronic rhinosinusitis also are frequently colonized with
staph aureus
Otitis media is frequently seen with what
chronic rhinosinusitis
bacterial rhinosinusitis is associated with what symptoms
-purulent nasal discharge
-facial pain or pressure
treatment of clear nasal discharge in rhinosinjusitis
-analgesics
-saline irrigation
-decongestants (caution in old people with HTN and BPH)
When to rx abx for rhinosinusitis
when symptoms are present for 7+ days and continue to worsen
CRS treatment
-saline irrigation
-topical nasal steroids (cause epistaxis)
S/S of asthma
-nocturnal wheezing/dyspnea
-cough
-chest tightness
-improvement of FEV1 of at least 12% after SABA is key
Diagnostic tests for asthma
-improvement of FEV1 of at least 12% after SABA is key
-Provication tests (methacholine challenge)
-sputum esinophilia
-elevated IgE
-elevated fractional excretion of nitric oxide
Diagnostic tests for COPD
-reduced and irreversible FEV1/FVC <70%
Symptoms of COPD
-dyspnea
-cough
-sputum production
-wheezing
-chest pain
COPD grading scale
mild: >80%
mod: 50-80%
severe: 30-50%
very severe <30% or FEV1 <50%
General COPD treatment
-inhaler therapies (bronchodialators and iCS)
-smoking cessation
-supplemental o2
-pulmonary rehabilitation
Interstitial lung disease
a spectrum of diffusee parenchymal and fibrotic lung injuries with interstitial pulmonary fibrosis being the most closely related to aging
simptoms of ILD
-clubbing
-dyspnea
-cough
-crackles
-rales
-restrictive ventilatory impairment on PFT
-diffuse intersititial opacities
-alveolointerstitial inflammation with fibrosis
IPF and ILD can mix with COPD and lead to what on pft
psudonormilization
ILD chest radiographs will show
-reticular opacities in the mid and low lung
-CT will show subplural reticulation and honeycombig
Risk factors for PE
-CANCER
-surgery
-fractures
-bed rest
-sedentary periods
criteria used for PE
wells and geneva
Diagnostic tests for PE
-D-dimer (although it increases with age anyway)
-Ultrasound for DVT
-CT pulmonary angiogram