6 Immunology

Question 1

hypersensitivity reaction types

example of each

Answer 1

1. fast response, anaphylaxis
2. antibody binds to a host cell, thinking it is a foreign cell. Grave’s disease, myasthenia gravis
3. immune complexes get stuck in joints, kidney. SLE
4. delayed hypersensitivity
   - contact dermatitis

Question 2

Pt with shock, 1 week post transplant. Thank what?

Answer 2

think: surgical infxn, acute rejection, GVH. Not opportunistic

Question 3

Pt with shock. 2 years post transplant, think what ddx

Answer 3

opportunistic infections, rejection, not GVH

Question 4

how to transfuse RBCs in transplant patients?

Answer 4

irradiated RBCs

other products do not need anything different