6 Gastrointestinal Disorder Flashcards

0
Q

RUQ nl physiology:

Also consider

A

RUQ: Cholecystitis, rt lower lobe pneumonia, acute hepatitis

Also consider. Biliary colic, pancreatitis, IBD, GERD, pleurisy, PE

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1
Q

Exam diagnostic tests-

What to order for RUQ pain?
LQ pain?
If u think bowel perferation?

A

Exam diagnostic tests-

What to order for RUQ pain? U/S!

or if Bowel perf or constipation suspected get a KUB. (Xray kidney ureter bladder)
For possible cholysistitis, Get a HIDA scan id US inconclusive

LQ pain? CT! For appendicitis, kidney stones, diverticulitis,
If u think bowel perferation?

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2
Q

Upper abdomen initial diagnostic testing

A
CBC
UA, hCG
LFTs (Hep panel if abn)
Lipase/ amylase - pancreatitis
KUB flat/ upright if perf suspected (kidneys,ureter, bladder frontal radiograph)  ***best and cheapest imaging is KUB = constipated

Then US!!!

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3
Q

EXAM***

What are sxs of acute cholecystitis?

A
Syndrome of 
RUQ pain
Fever
Leukocytosis (w Bands showing bad infxn)
Gallbladder inflammation (usually from a stone)
- pain is steady and severe
- usually have had previous attacks that went away
- malaise and fever
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4
Q

Acute cholecystitis. ***exam

What r US findings?
And classic sign?

A

Gallbladder wall thickening and edema

Sonographic “Murphy’s sign”: palpation of URQ pain

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5
Q

What happens when the cystic duct gets blocked?

A

Bile cannot drain from the gallbladder, infection sets in, acute cholecystitis

Fever, nausea, RUQ pain -Murphy’s sign

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6
Q

With RUQ pain and US inconclusive for acute cholecystitis, what next imaging study should be next?

A

HIDA scan

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7
Q

Acute cholecystitis treatment

A

Antibiotics

Surgery almost always reccomended to remove gallbladder

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8
Q

What is a HIDA scan?

A

Imaging to use when US inconclusive for gall bladder
HIDA is a dye used to demonstrate patency of of common bile duct and ampulla
Positive test= gall bladder was not visualized

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9
Q

Diagnosis?
May occur with or without gallbladder disease
RUQ severe pain and/or epigastric pain
Sever!!

A

Acute pancreatitis

Most go to ED pain so severe

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10
Q

3 etiologies of Pancreatitis

A

Gallstone induced: more common in women (blocks common bile duct
ETOH induced- more common in men(happens when they stop drinking
Hypertriglyceridemia- why we treat this now! In either gender when levels hit 2000-3000 watch out!!!

60-75% liklihood it is gallbladder or ETOH induced

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11
Q

Why do we treat triglycerides now?

A

To prevent Pancreatitis!!!

Not for cardiac reasons anymore- doesnt change outcomes

Nl levels are 150, and very high is >500
Very high levels 1000-3000. High risk for pancreatitis!!!

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12
Q

After 1-3 d of binge drinking, what can occur.

A

Pancreatitis!

Or from high triglycerides or gall bladder induced

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13
Q

LUQ pain and anatomy

Consider…

A

Pancreatitis, MI, left lower lobe pneumonia

Also consider. Gastritis, gastric ulcer, PUD, GERD, splenomegaly, pyelonephritis, PE, nephrolithiasis

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14
Q

KUB is a —- film

A

Scout film. Visualizes abdominal masses, calcifications, foreign bodies, intestinal obstruction, abdominal gas pattern, soft tissue shadows, organ configuration

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15
Q

What does dilated loops of bowel mean on a KUB?

A

Bowel obstruction! Move on it-refer!

Something cant pass so dilation gets bigger and bigger

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16
Q

A 56 yo man w abd pain has dilated loops of bowel on KUB xray. What is significance?

Constipation
Bosel obstruction
Diverticulitis
Colorectal disease

A

Bowel obstruction! Refer asap

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17
Q

With females and lower quadrant think:

A

Labs and exam first!

Labs: CBC. UA hCG. Lipase/amylase. CT!!

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18
Q

Lower quadrant imaging

A

CT

All picked up w CT

Appendicitis
Kidney stones
Diverticulitis
Appendicitis

19
Q

A 76 yo with lower abd pain present for several days

A

Think diverticulitis. Get CT

20
Q

What is McBurney’s point?

A

Point of maximum tenderness in RLQ showing inflammation of the vermiform appendix

21
Q

What r two appendicitis screens?

A

Appenicitis screens
Psoas sign. Raise right leg- pain bc appendix lies on ileo psoas muscle

Obturator sign- flex R knee at hip and internally rotate.

(Murphy’s sign is gallbladder- cup fingers under R rib breath in). Bc gallbladder higher up than appendix

22
Q

Clinical findings in Appendicitis

A

Mild leukocytosis (bands)
Mild elevations in bilirubin
Fever low grade

Needs surgical eval
Surgeon will do rectal bc all appendix’s hang in different positions- sometimes not in RLQ

23
Q

GERD

Acid levels of stomach and esophogus

A

Stomach-acid 1-3. Would burn finger
Esophagus acid level 3-5
So if stomach acid travels up esophagus will burn!

24
Q

Difference between physiologic and pathologic reflux

A

physiologic- occurs after eating, is short lived, and rarely occurs during sleep

pathologic reflux- associated w sxs- cough, hoarse, sore throat. Associated w mucosal injury
Nocturnal sxs
Big difference!

25
Q

3 reasons why reflux of gastrointestinal contents happens

A

-Reduction of LES(lower esophageal sphincter)tone
(If LES is lazy when acid comes it opens up!)

  • irritation of esophageal mucosa
  • increased gastric acid secretion
26
Q

How to prevent esophogeal CA?

A

If control GERD and inflammation (where bugs grow) u can decrease risks. 50 and smokers- BIG risk!!

27
Q

Who gets endoscopy?

A

Males >50 and smokers. BIG risk!!!

  • inadequate response to BID PPI -if pt using for at least 4-8 wks and still has sxs
  • dysphagia (difficulty swallowing)
  • odynophagia (pain w swallowing- esophogitis, esophogeal ulcer)
28
Q

What high risk pt.’s w brand new heartburn need referral?

A

Male Smokers >50 yrs

29
Q

Nonpharm mngt for GERD

A

avoid recumbence after eating for 2-3 hrs*

Elevate HOB when sleeping

Reduce size of meals

Reduce amt of fat, acid, spices, caffeine, sweets, peppermint, chocolate, and alcohol (may reduce esophogeal tone)

Smoking cessation

30
Q

Two PRN meds for GERD and 1 nonPRN

A

Antacids
H2 antagonists

Proton Pump Inhibitor- need to take every day of week that ends in y. For 4-8 wks if typical sxs

31
Q

Antacids

When provide relief?
What do they do?

A

Provide relief in 30 min
Fastest but short acting

Takes a pH from a 2 to 5, but in 30 min goes back to a 2

32
Q

H2 antagonists

When provide relief?
What do they do?

A

PRN
Take about 60-120 min to work
Provide relief for 6-12 hrs

Dont change pH, but decrease the amt of acid u r making

Ex. Cimetidine, Ranitidine, famotidine, Nizatidine

33
Q

Proton pump inhibitors. PPI

When provide relief?
What do they do?

A

Not PRN. Take BID for minimum of 4 wks. If sxs return - ENDOSCOPY!!!!

Reduce gastric secretion- dont change pH
Inhibits u from making protons (“H+”). When ur body smells food it it pairs with an “H” and a “Cl”- HCL to digest food. We make 2-3 d of “H” ahead so we have to take PPI ahead of time and can’t be PRN

34
Q

Recivitism

A

High rate of recurrence of sxs if meds are reduced or stopped

Sxs return when meds are stopped

35
Q

Complication of GERD?

A

Barrett’s esophagus:
Premalignant… Metaplastic columnar epithelium replaces stratified squamous epithelium

  • consequence of chronic GERD
  • predisposes patient to adenocarcinoma of the esophagus
36
Q

What is most common cause of Diarrhea?

  • E. Coli
  • viral infxn
  • Salmonella
  • bacteria
A

VIRAL!

37
Q

If Diarrhea lasts longer than 2-3 days consider

A

Lactose intol

-salmonella

38
Q

Name acronyms

IBS. Vs. IBD

A

IBS. Irritable bowel syndrome. 25% people have!

IBD- inflammitory bowel disease (ulcerative colitis and Crohn’s disease)

39
Q

What is the GI syndrome characterized by recurrent abdominal pain associated w altered defecation in the absence of disease

A

IBS

Irritable bowel syndrome

Neurotransmiter issue - Serotonin!

40
Q

Sxs of IBS

A

Crampy abd pain that varies in location and character
Diarrhea, constipation, alternating D and C with nl bowel habits
Mucus present

Wont kill u

*alternation- key characteristic

Me :(

41
Q

Red flag alarms with IBS

A

Rectal bleeding
Wt loss
Anemia elevated inflam markers, electrolyte disturbances

All Inconsistant with IBS!!!

42
Q

EXAM**

What is classic distribution of IBD?

A

(UC and Crohn’s)

Bimodal distribution: onset 15-40 yrs and 50-80 yrs with Bloody, nocturnal diarrhea, fever, fatigue

Refer GI - endoscopy

43
Q

Ulcerative Colitis (InflamBD)

What area affects?
Sxs?

A

Chronic inflam of MUCOSAL LAYER of COLON (get colonoscopy to examine all of colon; sigmoidoscopy only does last third of colon)

UC is Usually BLOODY (Crohn’s usually not), bloody loose stools, abd pain, fever

Almost always involves RECTUM

Gradual onset of sxs

44
Q

Main things to remember for

IBS
IBD - UC and Crohn’s

A

Main things to remember for

IBS- ALTERNATES diarrhea and contipation

IBD - UC - BLOODY diarrhea, rectal/colon

     Crohn's- NOT BLOODY diarrhea, end of small bowel(ileum) and beg of colon, but can affect any part of GI from mouth to anus  ie. Apthous ulcers, esphogitis
45
Q

IBD. Crohn’s disease (CD)

Area affects
What is diarrhea like?
Extra intestinal sxs?
How to diagnose?

A

IBD. Crohn’s disease (CD)

Area affects- transmural inflammation (across wall of organ)- usually end of small int(ileum) beg of colon. But can be
What is diarrhea like? Usually not visibly bloody
Extra intestinal manifestations? Arthritis, eyes (uveitis, iritis)
How to diagnose?colonoscopy