6. Endocrine Ds Flashcards
adrenal glands secrete what
cortisol, epi, NE, aldosterone, and adrenal androgens
(sex hormones and catecholamines)
adrenal glomerulosa
aldosterone
adrenal fasciculata
cortisol (glucocorticoid)
adrenal reticularis
androgens
NE and Epi actions
fight or flight - stress response
increase Bp, peripheral resistance, cardiac output
hyperadrenalism is what
increase of aldosterone, cortisol, androgen, estrogen isolated or in combo
hyperaldosteronism
HTN, hypokalemia, edema
glucocorticoid xs
is high levels of cortisol
and the MOST COMMON
(Cushing ds and syndrome)
CUSHINGOID memonic
signs and symptoms that as associated with cushing ds
C-cataracts
U- ulcers
S- striae and skin thinning
H- HTN and hirsutism
I- Immunosuppresion and infections
N- Necrosis of femoral heads
G- Glucose elevation
O- Osteoporosis and obesity
I- Impaired wound healing
D- Depression and mood changes
cushingoid moon face is a sign of
cushing ds or syndrome
not necessarily specific for cushings though.
why is cortisol used
it is used to decrease inflammation
bexamethasone
betamethason are what type of drugs
long-acting glucocoritcoids
used for oral ulcerations ( dexamethesome)
prednisolone
triamcinolone
methylprednisolone are what type of drugs
intermediate acting glucocorticoids
used topciallly (methyprednisolone)
primary adrenal insufficiency is what
addisons ds
increase ACTH decrease Cortisol.
what is this
cutaneous findings in addisons ( so primary adrenal insufficiency)
hyperpigmentation of skin and mucous membrance but they’re iregullarly shaped. It’s a variation of normal but could be addisons too.
hyperpigmentation and andrenal crisis do not usually ocur or are less likelly to occur in the secondary and teritary insufficiencies.
secondary adrenal insufficiency
decrease of cortisol and decrease of ACTH, aldosterone is unchaged.
tertirary adrenal insufficiency
most commonly a result of chronic exogenous steroid use