6. Chlamydiae & Mycoplasma

Question 1

What typed of chlamydiae is?

What’re characteristics of chlamydiae?

Answer 1

• Obligate intracellular pathogen

Question 2

What 2 forms of chlamydiae?

Answer 2

1- Elementary bodies

2- Reticulate bodies

Question 3

What is Eb?

Answer 3

It’s extra cellular & infective form of chlamydiae (no replication)

Question 4

What’s Rob?

Answer 4

It’s intacellular and replicative form of chlamydiae

Question 5

Why do chlamydiae need host?

Answer 5

Bus they differ from other bacteria:

• no peptidoglycan
• no ATP production
• biphasic growth cycle

Question 6

What is clinical features of C.trachomatis?

Answer 6

1- ocular infection
1) Trachoma => blindness very common in chlidren by flies & fingers in low socioeconomic
2) Adult inclusive conjunctivitis (self limiting) spread from genitalia to eye
2- genital infection

 1)  MALES

Question 7

What is clinical features of C. Psittaci?

Answer 7

Psittacosis / Ornitosis

Symptoms:
-atypical pneumonia

Question 8

Is Psittacosis/Ornithosis human or zoonotic infection

Answer 8

Non-human pathogen ——>zoonotic infection

Bird handlers

Question 9

How does C. Psittaci transmitted.

Answer 9

By infected droplets

Question 10

What are clinical infections/features of C. Pneumonia?

Answer 10

• otitis media & sinusitis (URT)

- pneumonia & bronchitis (LRT)

Question 11

C. Trachomatis & C. Pneumoniae infected by humans or zoonotic?

Answer 11

Only infect humans

Question 12

What is the characteristics of mycoplasma?

Answer 12

• smallest free living organism
• lack cell wall [no peptidoglycan] ——-> CANNOT see it in lab culture/growth media
• can grow in rich artificial media

Question 13

What are 3 types of mycoplasma?

Answer 13

• M. Pneumoniae
• M. Hominids
• M. Ureatyticum (ureaplasma ureatyticum)

Question 14

What are clinical features of M. Pneumoniae?

Answer 14

1- respiratory infections —> atypical pneumoniae
-more in children
- in summer ( European & North American countries) (spring in kw)
- prominent X-ray although the pe looks stable
- disease courses > 2 weeks
- hemolytic anemia ( +ve hemogluttinin test)
2- Extrapulmonary
-hemolytic anemia
- myocarditis

Question 15

What are clinical features of M. Hominids & M. Ureatyticum?

Answer 15

Genital infections (STD)
 1- male
      - non- gonococcal urethritis
 2- female 
      - pelvic inflammatory disease (PID) 
      - Abortion & preterm labor 
      - stillbirth