5.7.3 structure of mitochondrion Flashcards
cristae
inner highly-folded mitochondrial membrane
mitochondrial matrix
fluid-filled inner part of mitochondria
structure of mitochondria
- inner & outer phospholipid membrane = envelope
- outer membrane = smooth
- inner membrane = folded into cristae (large SA)
- proteins embedded in inner membrane & protein channels
- inter-membrane space between
- mitochondrial matrix = enclosed by inner membrane, semi-rigid & gel-like
what does the mitochondrial matrix contain
- mitochondrial ribosomes
- looped mitochondrial DNA
- enzymes for link reaction/Krebs cycle
what does the matrix contain? - link to function
- enzymes - catalyse stages of respiration reactions
- molecules of coenzymes NAD & FAD
- oxaloacetate - 4 carbon compound which accepts acetyl group from link reaction
- mitochondrial DNA - code for enzymes & other proteins
- mitochondrial ribosomes - proteins are assembled
structure of outer membrane - link to function
- phospholipid composition
- contain proteins = some form channels/carrier proteins allowing passage of molecules (eg, pyruvate) into mitochondrion
structure of inner membrane - link to function
- lipid composition
- less permeable than outer membrane to small ions (eg. hydrogen ions - protons)
- folds (cristae) give large SA for electron carriers & ATP synthase enzymes embedded
describe electron carriers (inner membrane)
protein complexes arranged in electron transport chains (involved in oxidative phosphorylation)
structure of intermembrane space (relate to function)
- between outer/inner layers of mitochondrial envelope
- involved in oxidative phosphorylation
- inner membrane in close contact with matrix = NADH & FADH can easily deliver hydrogens to electron transport chain
what does each electron carrier protein contain
cofactor = non-protein haem group containing an iron ion
what is the role of the cofactor on the electron carrier protein
accept/donate electrons, as becomes reduced (Fe2+) by gaining electron & becomes oxidised (Fe3+) when donating electron to next electron carriers
= oxido-reductase enzymes
describe the role of coenzymes on the electron carriers
uses energy released from electrons to pump protons from matrix to intermembrane space
describe the ATP synthase enzyme
- large
- protrude from inner membrane into matrix
- protons pass through them