5.5.9 controlling heart rate Flashcards
important roles of the circulatory system
- transport oxygen & nutrients (eg. glucose, fatty acids, amino acids) to the tissues
- removal of waste productions to prevent accumulation which may become toxic (eg. carbon dioxide)
- transport urea from liver to kidneys
- distribute heat around the body or deliver it to skin to be radiated away
how can the heart action be modified to allow the circulatory system to adapt to meet the tissues’ needs
- raise or lower heart rate (number of beats per minute)
- altering force of contractions of ventricular walls
- altering stroke volume (volume of blood pumped per beat)
what is the cardiac muscle described as
myogenic
which muscle has a higher myogenic rate
atrial muscle has a higher myogenic rate than the ventricular muscle
pacemaker of the heart
sinoatrial node (SAN)
describe the sinoatrial node (SAN)
- initiates waves of excitation which usually override myogenic action of cardiac muscle
- region of tissue that can initiate an action potential
- action potential travels as a wave of excitation over the atria walls, through the AVN (atrio-ventricular node) & down the Purkyne fibres to walls of ventricles = causes them to contract
what hormone does the heart muscle respond directly to
adrenaline in the blood = increases heart rate
what is heart rate controlled by at rest
= SAN
- set frequency at which it initiates waves of excitation
- frequency of excitation usually 60-80 per minute
- however, frequency of excitation waves altered by output from cardiovascular centre in medulla oblongata
cardiovascular centre & SAN
- nerves from cardiovascular centre in medulla oblongata of brain supply SAN
- nerves are part of autonomic nervous system
- nerves don’t initiate a contraction, but can affect frequency of contractions
how can the nerves from the cardiovascular centre affect frequency of contractions
- action potentials sent down sympathetic nerve (accelerans nerve) cause release of noradrenaline at SAN = increases heart rate
- action potentials sent down vagus nerve release acetylcholine = reduces heart rate
outline sensory input to cardiovascular centre
- stretch receptors in muscles detect limb movement = send impulses to cardiovascular centre, informing it extra oxygen may be needed soon (increases heart rate)
- chemoreceptors in carotid arteries, aorta & brain monitor pH of blood (when exercising, blood pH reduced as carbonic acid formed which will affect oxygen transport) = change in pH detected, sending action potentials to cardiovascular centre (increases heart rate)
- concentration of carbon dioxide in blood (when stop exercising, concentration of carbon dioxide in blood falls) = reduces activity of accelerator pathway (heart rate decreases)
- stretch receptors in walls of carotid sinus monitor blood pressure = if pressure rises too high, stretch receptors send action potentials to cardiovascular centre (heart rate decreases)
what happens if the mechanism controlling heart rate fails
= artificial pacemaker fitted
- delivers electrical impulse to heart muscle
- implanted under skin/fat on chest (or sometimes within chest cavity)
- may be connected to SAN or directly to ventricle muscle