PRE-,PERI-,POST-OP CARE AND SURGICAL COMPLICATIONS Flashcards
Risk factors for PROPHYLACTIC ANTIBIOTICS:
- Systemic? 4
- Local factors? 4
- Systemic factors
- Diabetes
- Corticosteroid use
- Obesity
- Age - Local factors
- Foreign body
- Electrocautery
- Wound drains
- Injection with epinephrine
Selection of antibiotics
- Should be adminitsered when?
- Most commonly given antibiotics for prophylaxis?
- Gram neg and anaerobic pathogens can be covered by what? 4
- Should be administered 60 min before incision
- Most commonly given drug:
Cefazolin (Ancef, Kefzol) - Gram-neg and anaerobic pathogens can be covered by:
- Cefotetan
- Cefoxitin
- Ceftizoxime
- Each with or without metronidazole (Flagyl)
Diabetic Pt
1. Surgical stress induces a neuroendocrine response which results in what? 3
- Pre-op eval includes assessment of what? 2
- PE? 4
- insulin resistance,
- increased hepatic glucose production, and
- impaired insulin production
- metabolic control and
- any diabetes-associated complications
- Feet
- Minor injuries
- Poor hygiene
- ulcers
Diabetic pt
1. Cardiac
Men have ______ the risk, women have ______ the risk
- Can have hypotension from what?
- Gastroparesis
Delay what? Risk of? - Infection
__________ has effect on immune system - Reduced blood flow decreases what?
- twice, 4x
- cardiac neuropathy
- gastric emptying and aspiration
- Hyperglycemia
- healing
THROMBOEMBOLIC DISEASE
Despite advances in prevention and treatment of what remains most common preventable cause of death? 2
150,000 to 200,000 deaths per year in US
- Risk factors? 4
- VTE, pulmonary embolism
- Risk factors
- Extent of surgery or trauma
- Duration of hospital stay
- Previous VTE
- Immobility
THROMBOEMBOLIC DISEASE Risk model/Caprini score 1. Very low risk scores? 2 2. Low risk scores? 2 3. Moderate risk scores? 2 4. High risk scores? 2
Risk model/Caprini score
- Very low risk
- General and abdominal-pelvic surgery with Caprini score of 0
- Plastic and reconstructive surgery with Caprini score 0-2 - Low risk
- General and abdominal-pelvic surgery with Caprini score of 1-2
- Plastic and reconstructive surgery with Caprini score 3-4 - Moderate risk
- General and abdominal-pelvic surgery with Caprini score of 3-4
- Plastic and reconstructive surgery with Caprini score 5-6 - High risk
- General and abdominal-pelvic surgery with Caprini score of 5 or more
- Plastic and reconstructive surgery with Caprini score of 7-8
THROMBOEMBOLIC DISEASE
1. Prevention: Primary Prophylaxis?
- Selecting appropriate option includes 4?
- Easy to administer
- Safe and effective
- No need for lab monitoring
- Cost effective
2.
- Early and frequent ambulation for patients at very low risk
- Mechanical methods for patients with contraindication to pharmacological prophylaxis at low risk
- Pharmacological for patients at moderate and high risk
- Combination for patients at very high risk
THROMBOEMBOLIC DISEASE
Medications
4
- LMW heparins preferred in high risk patients
- SQ once or twice daily - Low dose Unfractionated heparin (UFH) alternative
- 5000 units two hours pre-op then 8-12hrs post-op SQ - Warfarin
- Alternative to LMW/UFH - Aspirin
THROMBOEMBOLIC DISEASE
- Mechanical methods? 3
- Inferior vena cava filter is used when?
- Mechanical methods
- Intermittent pneumatic compression (IPC)
- Graduated compression stockings (GCS)
- Venous foot pump (VFP) - Inferior vena cava filter (IVC)
- Failure to adequate anticoagulation
- Absolute contraindication to anticoagulation
- CDC has defined an infection related to an operation that occurs at or near the surgical incision within _________ of the procedure, or within ________ if an implant is used
- Most common _________ infection
- Impact? 2
- 30 days, 90 days
- nosocomial
- Increase in mortality
- Increase cost to patient and hospital
SSI
- Epidemiology? 3
- Risk factors? 6
- Epidemiology
- Depend on population
- Size of hospital
- Experience of surgeon - Risk factors
- Surgical technique
- Prolonged surgery time
- Instrument sterilization
- Preop preparation
- Thermoregulation/glycemic control
- Medical condition of the patient
SSI surgical environment risk factors? 4
Surgical environment
- Personnel traffic
- Excessive use of electrosurgical cautery units
- Prosthesis or foreign body
- Need for blood transfusion
SSI presentation? 4
Presentation
- Localized erythema
- Induration
- Warmth
- Pain at incision site
SSI Tx? 3
- Prophylactic antibiotics
- Infected wounds
- Antibiotics
- What kind of antibiotics for tx after already infected?
2. What kind of labs to detect bug? 2
- Broad spectrum antibiotic with coverage of gram positive cocci
- Culture and gram stain reports
SSI Tx: Surgical technique prevention? 5
Surgical technique
- Limit electrocautery
- Closure subq tissue
- Skin closure
- Delayed closure and heal by secondary intention
- Limit hypothermia
HEMATOMA AND SEROMA
- What are these?
- Which is more common?
- Cause what? 2
- Presentation? 3
- Collection of blood or serum under the incision
- Hematomas more common
- Cause
- wound separation and
- infection - Presentation
- Appear a few days after surgery
- Swelling
- Pain
HEMATOMA AND SEROMA
- Tx? 2
- Prevention? 3
- Treatment
- Percutaneous drains
- Wound exploration (Packed and heal by secondary intention) - Prevention
- Closure of dead space
- Meticulous hemostasis
- Placement of drains controversial
FASCIAL DEHISCENCE
- What is it?
- Occur when in the post op period?
- Complication?
- Risk factors? 4
- Abdominal wall tension overcoming tissue or suture strength
- Occur late or early post-op period
- Complications are incisional hernia
- Risk factors
- Age
- Males
- COPD
- Ascites
FASCIAL DEHISCENCE
1. Suture
Main cause is failure to what? 3
- Presentation? 2
- Treatment?
- Prevention? 2
- remain anchored,
- knot failure,
- large stitch intervals
- Profuse serosanguinous drainage
- Popping sensation with abdominal bulge
- Closure in operating room
- Continuous mass closure or interrupted
- Internal or external retention sutures
Wound healing: Primary intention
1. How is the wound managed? 2
- May drain a small amount of what? 2
- Generally kept protected from getting wet with a plastic cover for _____ days depending on wound site, if allowed to get wet—shower only, no bathtub or hot tub
- Monitor for what? 4
- Wound closed with stitches or staples
- Covered w/ sterile dressing
- blood or serosangueness fluid
- 2-10
- erythema,
- swelling,
- warmth and
- drainage
Wound healing: Secondary Intention
1. What are not closed, sometimes other layers not closed allowed to granulate in? 2
- When do we use this? 3
- Should be managed how?
- Epidermas and dermas
- Usually if there has been
- contamination,
- an infected wound,
- peritonitis - Has to be packed daily to every other day w/ saline moistened gauze or sponges and covered w/ a sterile dressing
- Pulmonary complications? 3
- Occurs in what percent of pts?
- Accounts for what percent of peroperative mortality?
- Complications
- Hypoventilation
- Pneumonia
- Atelectasis - Occur in about a third of patients
- Accounts for half of perioperative mortality
CATEGORIES OF PULMONARY COMPLICATIONS:
5
- Atelectasis
- Infection (including bronchitis & pneumonia)
- Prolonged mechanical ventilation & respiratory failure
- Exacerbation of underlying chronic lung dz
- Bronchospasm
Physiology
1. Residual effects of anesthesia & post-op opioids depress what?
- Inhibition of what? 3
- After abdominal and thoracic surgery how are the following affected:
- Vitial capacity?
- Functional residual capacity? - What are these capacity changes due to?
- respiratory drive
- cough,
- impairment of mucociliary
- clearance of respiratory secretions
- After abdominal and thoracic surgery:
- Vital capacity reduced by 50-60%
- Functional residual capacity reduced by 30% - Due to diaphragmatic dysfunction and postop pain
Pulmonary compliction risk factors? 5
- Age: age > 50 yrs independent risk factor
- Chronic lung disease (COPD)
- Asthma: if controlled not a higher risk
- Smoking: > 20 pack year hx higher incidence of postop pulmonary complications
- General health status
What kind of general health problems comtribute to pulmonary complications? 2
- CHF increases risk
2. URI—best to postpone elective surgery until resolved
Pulmonary: Procedure-related risk factors? 4
- Surgical site: abdominal and thoracic (especially upper abdominal)
- Duration of surgery: those lasting > 3-4 hrs
- Type of anesthesia: regional vs general—more complications w/ general
- Type of neuromuscular blockade: using long acting agent (pancuronium) higher risk then w/ short acting agents
PRE-OP RISK ASSESSMENT
1. GOAL?
- What would help us identify this? 2
- PE: Note what? 4
- direct history to recognize chronic lung disease
- Reports of exercise intolerance
- Unexplained dyspnea or cough
- PE: note decreased
- breath sounds,
- rhonchi,
- wheezes or
- prolonged expiratory phase
Testing for Pulm
1. All patients undergoing lung resection should have pre-op what performed?
For all other procedures, lab tests are adjuncts to clinical evaluation
- pulmonary function tests
PFTs
1. Obtain for pts w/ what if clinically cannot determine if pt at their best baseline? 2
- Obtain for pts w/ what that remains unexplained? 2
- COPD or asthma
2. dyspnea or exercise intolerance
PULM testing
1. ABGs?
- CXR: obtain in who? 2
- no data support use of pre-op ABGs as helpful to stratify risk for post-op pulmonary complications
- Obtain in pts w/ known CVD
- In those > 50YO undergoing high risk surgical procedures
STRATEGIES TO REDUCE POST-OP PULMONARY COMPLICATIONS
1. COPD? 3
- Asthma? 1
- URI?
- COPD
- Combinations of bronchodilators, antibiotics and systemic steroids
- All pts should receive daily inhaled ipratropium or tiotropium
- Beta-agonists as needed - Asthma
- Well controlled w/ beta-agonists, peri-operative systemic steroids if needed - delay elective surgery in the presence of a viral URI
Patient education before lung procedures?
Patient education:
Lung expansion maneuvers—coughing, incentive spirometry, and deep breathing should be taught prior to surgery
INTRA-OPERATIVE STRATEGIES
- Use what when possible?
- For neuromuscular blockade use what instead of pnacuronium?
- _________ procedures in high risk pts?
- spinal or epidural when possible
- intermediate agents (vecuronium, atracurium)
- pnacuronium
POST-OP STRATEGIES
Lung expansion? 4
- Deep breathing exercises
- Incentive spirometry
- Adequate pain control
- Routine use of nasogastric tube increases post-op pulmonary complications
- What is a post-op fever defined as?
2. Most early post- op fever is caused by what? Resolves?
- Fever > 38° is common in 1st few days after major surgery
2. Most early post-op fever caused by inflammatory stimulus of surgery and resolves spontaneously
POST-OP FEVER
Describe the 5 Ws?
5 W’s
- Wind day 1-2
- Water day 3-5
- Walking day 4-6
- Wound day 5-7
- Wonder drugs day 7+
TREATMENT for post op fever?
3
- Remove unnecessary treatments including medications and catheters
- Suppress fever with Tylenol
- Antibiotics per clinical judgment/culture results
MALIGNANT HYPERTHERMIA
1. An uncommon and sometimes life-threatening reaction to some what?
- What drug categories are dangerous for this? 2
- anesthetic agents.
- Depolarizing muscle relaxants (Anectine)
- Potent inhalational agents:
MALIGNANT HYPERTHERMIA
Potent inhalational agents?
5
- Halothane
- Isoflurane
- Enflurane
- Desflurane
- Sevoflurane
MALIGNANT HYPERTHERMIA
Safe drugs?
8
- Barbiturates (Thiopental)
- Benzodiazepines (Midazolan, Diazepam, Lorazepan)
- Droperidol (Inapsine)
- Ketamine
- Local anesthetics (Lidocaine, Bupivacaine)
- Nitrous oxide
- Nondepolarizating muscle relaxants (pancuronion, rocuronium, vecuronium)
- Opioids (Morphine, Demerol)
Propofol
MALIGNANT HYPERTHERMIA
Clinical Manifestations
Signs of hypermetabolism
11
- Hypercarbia (the most sensitive indicator of potential MH in the OR)
- Skeletal muscle rigidity (the most specific sign)
- Tachycardia
- Tachypnea
- High temperature (usually a late sign of MH)
- Hypertension
- Cardiac dysrhythmias
- Acidosis
- Hypoxemia
- Hyperkalemia
- Myoglobinuria
MALIGNANT HYPERTHERMIA
PP? 3
- Genetic predisposition
- Increased intracellular Calcium
- Continuous muscle contraction
MALIGNANT HYPERTHERMIA: HOW DO WE KNOW??
3
What should be avoided in caring for this patient?
- Just because prior anesthetics have been uneventful does not mean that MH will not occur.
- Ask about any muscle cramps, progressive weakness after prior surgeries.
- Any family history of muscle disease or anesthetic problems
Succinylcholine (probably the most dangerous “triggering agent”) should be avoided in caring for this patient.
MALIGNANT HYPERTHERMIA
11 steps?
- Call for help; management is involved and difficult for one person.
- Stop triggering agents.
- Hyperventilate patient with 100% oxygen.
- Finish or abort procedure.
- Administer Dantrolene (2.5mg/kg bolus; may repeat 2mg/kg every 5 minutes, then 1-2mg/kg/h).
- Cool patient (cold IV normal saline, cold body cavity lavage, ice bags to body, cold nasogastric lavage, cooling blanket).
- Monitor and treat acidosis (follow serial arterial blood gases and administer sodium bicarbonate).
- Promote urine output (maintain >2ml/kg/h management; furosemide, mannitol).
- Treat hyperkalemia.
Insulin + D50W - Treat dysrhythmias with procainamide and calcium chloride.
- Monitor creatinine kinase, urine myoglobin, and coagulation for 24-48 hours.
SURGICAL CARE IMPROVEMENT PROJECT (SCIP): Preventable Complication Modules? 3
- Surgical infection prevention
- Cardiovascular complication prevention
- Venous thromboembolism prevention
SURGICAL CARE IMPROVEMENT PROJECT
PERFORMANCE MEASURES - PROCESS: Surgical infection prevention? 4
- Antibiotics*
- Glucose control in cardiac surgery patients
- Proper hair removal
- Normothermia in surgery patients
Surgical infection prevention: Antibiotics
- Administration when?
- Use of what recommended in guideline?
- Discontiinuation when?
- Administration within one hour before incision
- Use of antimicrobial recommended in guideline
- Discontinuation within 24 hours of surgery end
- PRE-OPERATIVE SHAVING: Shaving the surgical site with a razor induces what?
- Other risks? 3
- Patient education?
- small skin lacerations
- potential sites for infection
- disturbs hair follicles which are often colonized with S. aureus
- Risk greatest when done the night before
- be sure patients know that they should not do you a favor and shave before they come to the hospital!
TEMPERATURE CONTROL
Helps us prevent what?
SSI
-treatment - active warming (mean temp on arrival to recovery 36.6°C)
Prevention of cardiac events: Myocardial ischemia either clinically occult or overt confers a 9 fold increase in risk of what? 3
- unstable angina,
- nonfatal myocardial infarction,
- and cardiac death
SURGICAL CARE IMPROVEMENT PROJECT
Prevention of Perioperative cardiac events?
Perioperative beta blockers in patients who are on beta blockers prior to admission
PREVENTION OF VENOUS THROMBOEMBOLISM
8
- Hospitalization/Nursing home** 61.2 %
- Active malignant neoplasm
- Trauma
- CHF
- CV catheter
- Neurologic disease with paresis
- Superficial vein thrombosis
- Varicose veins/stripping
PREVENTION OF VENOUS THROMBOEMBOLISM
Despite the well known risk of VTE and the publication of evidence-based guidelines for prevention, previous medical record audits have demonstrated underuse what?
-of prophylaxis
VTE prophylaxis a must!
SCIP-1-2-3 ANTIBIOTICS
APPROPRIATE, PRE-INCISION TIMING, D/C TIME
Antibiotics
1. Given when?
2. Which drugs do you give two hours before? 2
3. Discontnued when?
-Unless?
- Given on time: 1 hour before incision,
- 2 hrs – Vancomycin & Levaquin
- Discontinued within 24 hour after anesthesia end time
- (exception: 48 hours for cardiovascular surgery)
Name the preferred med for the following surgery: Adult Surgery Procedure 1. Cardiac? 1 2. Vascular? 1 3. Hip/Knee Arthroplasty? 1 4. Colon? 5 5. Hysterectomy? 4
No history of Penicillin OR Cephalosporin Allergies = rash
- Cefazolin (Ancef®)
- Cefazolin (Ancef®)
- Cefazolin (Ancef®)
- Cefotetan
- Ertapenem (Invanz®) x 1 dose only
- Cefoxitin (Mefoxin®)
- Ampicillin/Sulbactam (Unasyn®)
- Cefazolin + Metronidazole (Flagyl®)
- Cefazolin (Ancef®)
- Cefotetan
- Ampicillin/Sulbactam (Unasyn®)
- Cefoxitin (Mefoxin®)
Name the preferred med for the following surgery if Yes, history of Penicillin OR Cephalosporin Allergies Adult Surgery Procedure 1. Cardiac? 2 2. Vascular? 2 3. Hip/Knee Arthroplasty? 2 4. Colon? 5 5. Hysterectomy? 5
- Vancomycin**
- Clindamycin
- Vancomycin**
- Clindamycin
- Vancomycin**
- Clindamycin
- Levofloxacin (Levaquin®) + Metronidazole (Flagyl®)
- Gentamicin + Metronidazole (Flagyl®)
- Clindamycin + Gentamicin
- Clindamycin + Aztreonam
- Clindamycin + Levofloxacin (Levaquin®)
- Clindamycin + Gentamicin
- Levofloxacin(Levaquin®) + Metronidazole (Flagyl®)
- Clindamycin + Aztreonam
- Clindamycin + Levofloxacin (Levaquin®)
- Gentamicin + Metronidazole (Flagyl®)
IF USING VANCO
**If Vancomycin is marked on the physician order and patient does NOT have any allergies, one of the following needs to be documented?
7
- MRSA, Colonization or infection
- Patient with an acute inpatient hospitalization within the last year
- Patient residing in a nursing home within the last year
- Patient with chronic wound care or dialysis
- Patient with continuous inpatient stay more than 24 hours prior to the principal procedure
- Patient transferred from another inpatient hospitalization after a 3 day stay
- Patient undergoing valve surgery
RE-DOSING Which meds need to be redosed in the following timelines: 1. 2 hours? 2 2. 3 hours? 1 3. 4 hours? 2 4. 6 hours? 2 5. 12 hours? 1
- -Cefoxitin
-Ampicillin/
sulbactam - Cefotaxim
- Cefazolin
- Aztreonam
- Cefotetan
- Clindamycin
- Vanco
- SCIP-4 BLOOD GLUCOSE under what?
2. Cardiac surgery patients – controlled ____ postoperative serum glucose (less than _____ mg/dl postop day 1 and 2)
- 200
2. 6AM, 200
SCIP-6 HAIR REMOVAL?
Hair Removal
Clippers in OR only-no other option
SCIP-9 FOLEY D/C
1. Discontnue when?
- Unless?
- Urinary Catheter
- Discontinued by postop day 2 - Or physician, PA, NP documented reason to continue beyond day 2
SCIP-CARDIAC-2, BETA BLOCKER
- If pt is on home beta blocker?
- Beta blocker may be given when prior to op or day of procedure (up to 12 midnight)?
- heart rate must be ≥ ___ and systolic blood pressure ≥ ____
- If held according to parameters, physician, PA, APN reason must be what?
- Then Beta blocker continued postop days ______?
(Physician, PA, APN documented reason if held postop)
- Continue if patient on home beta blocker therapy
- 24 hrs
- 50, 100
- documented
- 1 & 2
SCIP-VTE-2 TIMING OF VTE PROPHYLAXIS
1. Mechanical and/or pharmacological prophylaxis is ordered according to what? 2
- Prophylaxis is given____hrs. prior to surgery or within ____ hours after anesthesia end time
- Provider documentation required if contraindicated such as? 2
- VTE risk assessment tool and type of surgery
- 24, 24
- open wound,
- bleeding risk.
RECOMMENDED VTE PROPHYLAXIS
Pharmacological VTE Prophylaxis is required for surgeries below unless contraindication is documented. Applicable for surgeries of 60 minutes or greater
1. General and Colorectal Surgery? 2
2. Unless? 2
- Heparin
- Enoxaparin/Lovenox
- If contraindication to above is documented, then:
- Graduated compression stockings
- Sequential compression devices
RECOMMENDED VTE PROPHYLAXIS
Pharmacological VTE Prophylaxis is required for surgeries below unless contraindication is documented. Applicable for surgeries of 60 minutes or greater
1. Elective Hip Replacement? 4
2. Unless? 2
- Enoxaparin/Lovenox
- Fondaparinux/Arixtra
- Warfarin/Coumadin
- Rivaroxaban/Xarelto
If contraindication to above is documented, then:
- Venous foot pumps
- Sequential compression devices
RECOMMENDED VTE PROPHYLAXIS
Pharmacological VTE Prophylaxis is required for surgeries below unless contraindication is documented. Applicable for surgeries of 60 minutes or greater
1. Hip fractures? 4
2. Unless? 3
- Heparin
- Fondaparinux/Arixtra
- Enoxaparin/Lovenox
- Warfarin/Coumadin
If contraindication to above is documented, then:
- Graduated compression stockings
- Venous foot pumps
- Sequential compression devices
Pharmacological or Mechanical VTE Prophylaxis is required for surgeries below. Applicable for surgeries of 60 minutes or greater. Patients should be evaluated for risk factors for VTE.
- Elective Total Knee Replacement 6
- Urologic Surgery 4
- Gynecological Surgery 3
- Intracranial Neurosurgery 3
- Enoxaparin/Lovenox
- Warfarin/Coumadin
- Rivaroxaban/Xarelto
- Fondaparinux/Arixtra
- Venous foot pumps
- Sequential compression devices
- Heparin
- Enoxaparin/Lovenox
- Sequential compression devices
- Graduated compression stocking
3.
- Heparin
- Enoxaparin/Lovenox
- Sequential compression devices
- Heparin
- Enoxaparin/Lovenox
- Sequential compression devices
SCIP-10 NORMOTHERMIA measures?
Temperature Management
At least ≥ 96.8°F/36°C within 15 minutes of anesthesia end time or warmer used in OR
Exception: Provider documentation of intentional hypothermia
Name the CURRENT SCIP MEASURES? 9
- SCIP-1 Pre-op Antibiotic given within 1 hr. before incision
- SCIP-2 Must receive SCIP recommended prophylactic antibiotic
- SCIP-3 Discontinue antibiotic within 24 hrs. of anesthesia end time
(cardiac op exception) - SCIP-4Controlled 6 am postoperative serum glucose (cardiac only)
- SCIP-6 Appropriate hair removal
- SCIP-CARD-2 Perioperative beta-blocker therapy for pre B blocker Rx
- SCIP-VTE-2 VTE prophylaxis within 24 hrs. prior to or after anesthesia end time
- SCIP-9 Remove urinary catheter by postop day 2
- SCIP-10 Temperature >96.8 F- 15 min. after anesthesia end time