5 genetic toxicology

Question 1

Genetic toxicology

Answer 1

is the branch of toxicology that assesses the effects of chemical and physical agents on DNA and the genetic processes of living cells.

Question 2

Mutation

Answer 2

– a change in genetic material:
Random change in a gene or chromosome resulting in a new trait or characteristic that could be inherited if it took place in a germ cell

Question 3

Mutagen:

Answer 3

Mutagen:
A physical or chemical agent that changes the genetic information (DNA) of an organisms and thus increases the frequency of mutations above natural background level

Question 4

Clastogen

Answer 4

A material that causes breaks in chromosomes leading to sections of the chromosome being deleted, added or rearranged. This form of mutagenesis can lead to carcinogenesis.

Question 5

Oncogenes

Answer 5

Genes that stimulate the transformation of normal cells into cancer cells.

Question 6

Aneuploidy

Answer 6

Abnormal chromosome numbers.

Question 7

Chromosomes were discovered by?

Answer 7

Chromosomes were discovered by C.Von Nageli in 1842

Question 8

The term chromosome means and named by?

Answer 8

The term chromosome (W. Waldyer – 1888) means colored body.

Question 9

chromatin

Answer 9

The nucleoprotein material of chromosomes is referred to as chromatin.

Question 10

Centromere

Answer 10

Centromere – is the constriction in the chromosome and is composed of nucleoprotein