5. Defending Against Disease Flashcards

1
Q

What are pathogens?

A

Microorganism so that cause infectious diseases.

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2
Q

What are infectious diseases?

A

Diseases that can spread easily.

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3
Q

What are the two main types of pathogen?

A

1) Bacteria

2) Viruses

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4
Q

What are bacteria?

A

Very small cells (about 1/100th the size of body cells) which can reproduce rapidly inside the body.

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5
Q

How can bacteria make you ill?

A

1) Damaging body cells

2) Producing toxins

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6
Q

Are viruses cells?

A

No, they are much smaller than that.

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7
Q

What are viruses?

A

Microorganisms much smaller than bacteria (about 1/100th the size of a bacterium).

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8
Q

How do viruses make you ill?

A

They invade your cells and use the cells’ machinery to produce many copies of themselves until the cell bursts and the process repeats. The cell damage makes you feel ill.

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9
Q

How does your body defend against diseases?

A

1) Skin, hair and mucus stop pathogens getting in.
2) Platelets form clots to quickly seal wounds and stop pathogens getting in.
3) Immune system (especially white blood cells) attacks pathogens

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10
Q

How do white blood cells defend against pathogens?

A

1) Engulfing foreign cells and digesting them
2) Producing antibodies
3) Producing antitoxins to counteract toxins produced by invading bacteria

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11
Q

What are antigens?

A

Unique molecules found on the outside of invading cells.

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12
Q

What are antibodies?

A

Proteins produced by white blood cells that can lock onto foreign antigens and kill the pathogens.

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13
Q

How do white blood cells use antibodies to fight pathogens?

A

1) If a foreign antigen is detected, the white blood cells start to produce antibodies to lock onto them and kill the pathogen.
2) Antibodies are then produced rapidly and carried around the body to kill all similar bacteria and viruses.
3) Next time the same pathogen is detected, the body can produce the antibodies far faster.

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14
Q

How do vaccinations work?

A

1) A small amount of a dead or inactive pathogen is injected into a patient.
2) These pathogens still have antigens, which prompts the body to produce antibodies to attack them.
3) The body can store the antibodies.
4) Now if these pathogens ever invade the body, the white blood cells can rapidly produce the right antibody to kill the pathogen.

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15
Q

Why are booster injections sometimes needed?

A

The vaccinations “wear off” over time and booster injections may be needed to increase levels of antibodies again.

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16
Q

How can a pathogen be made harmless before it is used in a vaccine?

A
  • Injecting dead pathogens
  • Injecting weakened versions of the disease
  • Injecting inactive pathogens made harmless through: radiation, heat, chemicals
  • Injecting harmless toxins
  • Injecting only the antigens
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17
Q

How does the MMR vaccine work?

A

Weakened versions of measles, mumps and rubella are injected into the body.

18
Q

What are the pros of vaccination?

A

1) Vaccines have helped control lots of infectious diseases that were once common in the UK (e.g. Smallpox no longer exists and polio infections have fallen by 99%)
2) Epidemics can be prevented if a large percentage of a population is vaccinated. Even those not vaccinated are unlikely to get ill because there are few people who they can catch it from.

19
Q

What are the cons of vaccination?

A

1) Vaccines don’t always work

2) You can get a bad reaction to a vaccine (although this is rare)

20
Q

What is an epidemic?

A

A large outbreak of disease.

21
Q

What are painkillers?

A

Drugs that relieve pain. They don’t tackle the cause of the disease, but do reduce symptoms.

22
Q

Give an example of a painkiller.

A

Aspirin

23
Q

What are antibiotics?

A

Drugs which kill (or prevent the growth of) the bacteria causing a disease without killing your own cells.

24
Q

Give an example of an antibiotic.

A

Penicillin

25
Q

Are pathogens diseases?

A

No, they CAUSE the diseases.

26
Q

Can any antibiotic kill any bacteria?

A

No, different antibiotics kill different bacteria so you have to be treated by the right one.

27
Q

Do antibiotics destroy viruses?

A

No

28
Q

Why can’t antibiotics destroy viruses?

A

Viruses reproduce inside your own body cells, which means the antibiotics cannot reach them without destroying body cells.

29
Q

Give an example of a bacterial disease.

A
  • Salmonella

- Pneumonia

30
Q

Give an example of viral diseases.

A
  • Flu

- Measles

31
Q

How can bacteria become resistant to antibiotics?

A

1) Bacteria can mutate and sometimes this makes them resistant to an antibiotic.
2) When the antibiotic is used to treat the virus, only the non-resistant bacteria are killed.
3) The resistant bacteria now have space to reproduce and the population of the resistant strain increases.
4) Antibiotics no longer work on this new strain.

32
Q

Give an example of an antibiotic-resist bacteria strain.

A

MRSA (methicillin-resistant Staphylococcus aureus) causes serious wound infections and is resistant to the powerful antibiotic, methicillin.

33
Q

What are the dangers of antibiotic resistance?

A
  • Bacteria can spread rapidly through a population
  • No immunity and no effective treatment
  • Risk of epidemic
34
Q

How can the rate of development of antibiotic resistant strains be decreased?

A
  • Doctors have to avoid over-prescribing antibiotics

- Doctors have to avoid using them inappropriately (e.g. Not for only a sore throat)

35
Q

Is antibiotic resistant becoming more of a problem and why?

A

Yes, because of overuse and inappropriate use of antibiotics.

36
Q

What are superbugs?

A

Bacteria that are resistant to most known antibiotics.

37
Q

How have drug companies responded to antibiotic resistance?

A

They have worked on developing new antibiotics which are effective against resistant strains.

38
Q

How can antibiotics be investigated in a lab?

A

1) A Petri dish is filled with agar jelly.
2) Inoculating loops are used to transfer microorganisms onto the Petri dish. The microorganisms then multiply.
3) Paper disks are soaked in different antibiotics and placed onto the dish. The antibiotics diffuse into the jelly.
4) Resistant bacteria will continue to grow on the agar around a disc, while non-resistant bacteria will die.
5) A dry paper disk is used as a control.
6) The more effective an antibiotic, the larger the clear area around the paper will be.

39
Q

Where can bacteria be grown (cultured)?

A

In a culture medium. This is usually agar jelly (containing carbohydrates, minerals, proteins and vitamins).

40
Q

At what temperature are bacteria grown in school labs and why?

A

About 25*C because harmful pathogens are unlikely to grow at this temperature.

41
Q

At what temperature are bacteria grown in industrial conditions and why?

A

Higher than in school labs be as they grow a lot faster this way.

42
Q

How can contamination be prevented in bacterial experiments (like the one in this chapter)?

A

1) Petri dish and culture medium must be sterilised before use.
2) Inoculating loop used to transfer bacteria must be sterilised by passing it through a flame.
3) Petri dish should have a lid kept on before bacteria are transferred to culture medium to stop microorganisms from air getting in.
4) While transferring bacteria, lid should only be lifted slightly to stop microorganisms from air getting in.
5) After transferring bacteria, lid should be gently taped on to stop microorganisms from air getting in.
6) Petri dish should be stored upside down to stop bacteria falling onto the agar surface.