5 - Biological Rhythms Flashcards
Define biological rhythms
Distinct patterns of changes in body activity (controlled by internal + external factors) that conform to cyclical time periods
What two things are all biological rhythms regulated by?
- Endogenous pacemakers
- Exogenous zeitgebers
What are endogenous pacemakers?
- Internal factors
- Work as an internal body clock to regulate biological rhythms
- E.g. suprachiasmatic nucleus (involved in sleep-wake cycle)
What are exogenous zeitgebers?
- External factors
- Changes in the environment that influence our body clock + rhythms
- E.g. light + social cues (involved in sleep-wake cycle)
What are the three types of biological rhythms?
- Circadian rhythms
- Infradian rhythms
- Ultradian rhythms
Define circadian rhythms
Biological rhythms that occurs in cycles once every 24hrs
What is the example of circadian rhythms we use?
Sleep-wake cycle
What is the sleep-wake cycle?
A circadian rhythm (usually 8 hrs sleep every 24hrs)
Causes us to feel awake/alert in the day and drowsy at night
What exogenous zeitgebers influence the sleep-wake cycle?
- Light
- Social cues
What endogenous pacemakers influence the sleep-wake cycle?
Suprachiasmatic nucleus (SCN)
What is the Suprachiasmatic nucleus (SCN)?
- Endogenous pacemaker involved in the sleep-wake cycle
- Bundle of nerves in the hypothalamus working a an internal body clock
Outline how the SCN works in the sleep-wake cycle?
- Nerve fibres in the eye cross in the optic chiasm
- SCN sits just above the optic chiasm
- SCN detects light in the optic chiasm as its being sent to visual cortex
- SCN sends info to pineal gland about whether its light or dark
- If dark: pineal gland produces melatonin (inducing sleep)
- If light: pineal gland is prohibited from producing melatonin (preventing sleep)
What are two pieces of research on the sleep-wake cycle (circadian rhythm)?
- Siffre (cave study)
- Folkard et al (cave study, changing clock)
Outline Siffre’s cave study 1962 (aim, process, findings, conclusion)
Aim: to see if we have endogenous pacemakers causing our sleep-wake cycle
Process: spent 2 months isolated in a cave - no sunlight or clock
Findings: body chose when to eat and sleep, settled into a sleep-wake cycle of 25-30hrs
Conclusion:
- Supports existence of endogenous pacemakers: settled into a regular cycle of approx 25hr day
- Supports existence of exogenous zeitgebers: cycle wasn’t ‘norm’ of 24hrs
Outline Folkard’s cave study 1985 (aim, process, findings, conclusion)
Aim: to see if our internal body clock can be overridden by exogenous zeitgebers
Process: 12 ppts spent 3 weeks in dark cave. Told to go to bed when clock said 11:25pm + wake up at 7:45am. Changed clock to 22hr day.
Findings: Only 1 ppt could comfortably adjust to new regime
Conclusion:
Our internal body clock is very strong + it is very hard to override using exogenous zeitgebers
What is the natural length of humans’ sleep-wake cycle?
Slightly over 24hrs
What is the sleep-wake cycle length for humans? Why?
24hrs
- Naturally slightly longer
- Entrained by exogenous zeitgebers
What happens if the sleep-wake cycle is disrupted?
- Poor health
- Low concentration
- High anxiety
Give 2 positive evaluation points for circadian rhythms
Real world application (shift work)
- Understanding circadian rhythms can help improve conditions for shift workers
- Night shifts can disrupt sleep-wake cycle pattern + cause…
Circadian troughs (reduced conc - usually at 6am)
Poor health (3x more likely to get heart disease)
- Have concluded we should reduce shift work + give readjustment periods
- So, research has helped improve health + conc (+ productivity)
Real world application (medical treatment)
- Understanding circadian rhythms has contributed to chronotherapeutics
- If medicine is given at specific times (corresponding to rhythms) treatment will be more effective
- E.g. rhythms make heart attacks most common in early morning, novel medicine given at 10pm to release early morning, reduced heart attacks
- Understanding bodily rhythms over the day (circadian) improved treatment