4a. Sensory Systems Flashcards
Taste Receptors
Characteristic distribution, regions are a mixture
Some overlap in response
Taste is a combination of the categories
Tongue also has mechanoreceptors and thermoreceptors
Taste Receptors: Categories
sour (foliate papillae) sweet (fungiform papillae) salty (fungiform papillae) bitter (circumvallate papillae) umami (fungiform papillae)
Taste Buds
Location of taste receptors
On tongue and other areas of mouth
Grouped in each of 3 types of papillae on tongue
1 bud = ~50 receptors
Taste Receptor: Hairs
Project into taste pore - pick up taste stimuli
Taste Transduction
- Dissolved substances initiate transduction (substance must be dissolved in saliva to come in contact with R)
- Depolarizing R potentials
- Some taste R have voltage gated Na channels, make AP and release ATP
- Other taste R have voltage gated Ca channels and release vesicles of ATP (ATP release as NT - depolarizes primary afferent nerve ending)
- Peripheral endings of CN VII, IX, X depolarize - fire faster
CN for Conscious Perception of Taste
CN VII Facial
CN IX Glossopharnygeal
CN X Vagus
Mostly 7 and 9
Taste Receptors: Modified Epithelial Cells
Depolarizing receptor potentials –> release of NT ATP –> AP in primary neuron
Salt
NaCL
Sour
H+ in citric acid
Sweet
Sugar (glucose)
Bitter
Alkaloids (quinine)
Umami
L glutamate
Taste Pathways
- taste receptors
- cranial nerves (1 neuron)
- brainstem - nucleus solitarius (2 neuron)
- Thalamus (3 neuron)
- Gustatory cortex - insula
Limbic System
Provides affective dimension of taste (emotional context)
Olfactory Receptors
primary afferent neurons - not a separate cell
In olfactory mucosa
Odorant molecules bind to receptors in cilia in mucus layer
CN I (olfactory) goes through cribriform plate to connect with olfactory receptor in olfactory mucosa
Olfactory Transduction
- Olfactory R binds odorant molecules –> activates G protein
- Increase in intracellular cAMP
- cAMP gated cation channels open - Ca2+ enters
- Depolarization - Cl- leaves through Ca2+ gated Cl- channels
- Depolarization travels to initial segment of olfactory nerve
- AP generated
Axons from olfactory receptors leave olfactory epithelium …
Travel ventrally to olfactory bulb - pass through cribriform plate
fractures of cribriform plate can sever olfactory neurons –> disorders
Odor Discrimination
Enabled by variations in receptor molecule
Olfactory Pathway
- olfactory receptors (1 neuron: CNI (olfactory))
- olfactory bulb: apical dendrites of mitral cells (2 neuron)
- primary olfactory cortex (piriform cortex)
Also project to amygdala, limbic system
NO RELAY IN THALAMUS
Outer Ear (anatomy, function)
Direct sound through ear canal to tympanic membrane
helix
auricle
auditory canal
earlobe