48 Flashcards
A patient must be treated immediately for acute organ transplant rejection. The nurse anticipates that muromonab-CD3 (Orthoclone OKT3) will be ordered. What is the priority assessment before beginning drug therapy with muromonab-CD3?
Fluid volume status
A patient is about to undergo a kidney transplant. She will be given an immunosuppressant drug before, during, and after surgery to minimize organ rejection. During the preoperative teaching session, which information will the nurse include about the medication therapy?
Several days before the surgery, the medication will be administered orally.
A patient has an order for cyclosporine (Sandimmune). The nurse finds that cyclosporine-modified (Neoral) is available in the automated medication cabinet. Which action by the nurse is correct?
Notify the pharmacy to obtain the Sandimmune form of the drug.
The nurse is preparing to administer an injection of monoclonal antibodies. Which additional drug will the nurse administer to minimize adverse reactions to the monoclonal antibodies?
A corticosteroid
When administering cyclosporine, the nurse notes that allopurinol is also ordered for the patient. What is a potential result of this drug interaction?
Increased levels of cyclosporine and toxicity
The nurse is monitoring a patient who is receiving muromonab-CD3 (Orthoclone OKT3) after an organ transplant. Which effect is possible with muromonab-CD3 therapy?
Chest pain
When monitoring a patient who is on immunosuppressant therapy with azathioprine (Imuran), the nurse will monitor which laboratory results?
White blood cell (leukocyte) count
A patient with multiple sclerosis will be starting therapy with an immunosuppressant drug. The nurse expects that which drug will be used?
Glatiramer acetate (Copaxone)
Cyclosporine is prescribed for a patient who had an organ transplant. The nurse will monitor the patient for which common adverse effect?
Hypertension
The nurse follows which procedures when giving intravenous (IV) cyclosporine? (Select all that apply.)
Using an infusion pump to administer this medication
Monitoring the patient closely for the first 30 minutes for severe adverse effects
Checking blood levels periodically during cyclosporine therapy
Performing frequent oral care during therapy
- A patient has started azathioprine (Imuran) therapy as part of renal transplant surgery. The nurse will monitor for which expected adverse effect of azathioprine therapy? (Select all that apply.)
Leukopenia
Thrombocytopenia
Hepatotoxicity
