4.3 Physiology of Somatic Motor System Flashcards
Functions of somatic motor system
4
General functions of the somatic motor system
- Skilled, voluntary skeletal muscle activity
- Subconscious adjustment of posture
- Subconscious coordination of different muscle groups to make movements smooth and precise
- Subconscious protective reflexes -
___________- a.k.a. ventral anterior horn cell, α-motor neuron, efferent neuron to skeletal muscle, or somatic efferent neuron
lower motor neuron - a.k.a. ventral anterior horn cell, α-motor neuron, efferent neuron to skeletal muscle, or somatic efferent neuron
“final common pathway” is?
through?
The lower motor neuron through
spinal and cranial nerves
Higher centers that regulate lower motor neuron- c p v r B C SR
1-cerberal cortical motor areas/cerebral cortex/precentral gyrus
…corticospinal/pyramidal tract, corticobulbar/corticonuclear tract
2-Extra pyramidal tract..Vestibulospinal tract and Reticulospinal tract
3-Basal nuclei and accessories
i. Basal nuclei (caudate nucleus, globus pallidus, putamen)
ii. Substantia nigra (a cluster of neurons in the midbrain)
iii. Subthalamic nucleus
- cerebellum
- spinal reflex arcs
What are the three descending motor pathways
c
r
v
corticospinal tracts
Reticulospinal tract
Vestibulospinal tract
neither the ____ nor the ____ have any direct connections with the lower motor neurons
basal nuclei, cerebellum
Neurons from many areas of the CNS can affect somatic motor function but they all eventually pass information to the _____ located in the anterior horns of the spinal cord or similar areas in the brain stem
lower motor neurons
work by influencing the function of the descending tract above
2
basal nuclei, cerebellum
- A lower motor neuron must integrate many input signals ______ arriving continually from several different areas of the nervous system
(IPSPs or EPSPs)
most descending fibers that control motor activity synapse on ____ vs. lower motor neurons
interneurons
(IPSPs or EPSPs) integrate
at the axon hillock
The lower motor neurons are called the final pathway because
only lower motor neurons actually stimulate skeletal muscle
The corticospinal tract originates from the following areas:
1.
2.
3.
- The motor cortex (area 4)
- The supplemental and pre-motor cortex (area 6)
- The parietal cortex (areas 3,1,2)
- The motor cortex is connected to the final common pathway via _____, ______,and _____
the lateral and ventral corticospinal tract, corticobulbar upper motor neurons
This area is chiefly concerned with skilled, voluntary movements of the hands and face ( as seen on the motor homunculus)
the lateral and ventral corticospinal tract, corticobulbar upper motor neurons
Most neurons emanating from the motor and premotor cortical areas synapse on____, which in turn synapse on the lower motor neurons.
interneurons
Most of these interneurons are ____ and prevent lower motor neurons from over-discharging when responding to reflex stimulation
inhibitory
Injury to upper motor neurons can abolish or lessen the output of these inhibitory interneurons to lower motor neurons; the result could be _____
hyperreflexia or increased muscle tone
The motor system relies on sensory feedback for control of voluntary movements. This feedback comes from:
4
senses
- Sensory receptors in muscles and joints (proprioceptors)
- Visual input
- Vestibular input from the internal ear (equilibrium)
- Pressure and touch receptors in the body surface
Effects of injury to corticobulbar or corticospinal tract upper motor neurons; most commonly caused by stroke would include:
- Spasticity (involuntary movements) and exaggerated reflexes (hyperreflexia)
- Loss of voluntary movement
- Profound weakness or paralysis affecting the face (corticobulbar), trunk (ventral corticospinal) and extremities (lateral corticospinal)
- Depressed or absent superficial reflexes
These reflexes are elicited by cutaneous afferents, require intact upper motor neurons and are polysynaptic.
superficial reflexes
- These reflexes are typically elicited by the muscle receptors (e.g., muscle spindle), do not require an upper motor neuron but only a lower motor neuro and are typically monosynaptic.
Deep reflexes
Big toe goes up and toes fan apart when the sole of the foot is stroked from heel-to-toe (thus, a superficial reflex)
Babinski sign
Normally seen in infants but not in adults
Would Indicate damage to an upper motor neuron
The main subcortical Motor Area:
Basal nuclei
The basal nuclei do not have any direct influence on the final common pathway. It is part of a ____ that considers various courses of action before the final movement plan is sent down the corticospinal tracts
“movement planning circuit”
In essence, the basal ganglia are part of a _____
corticocortical loop that is superimposed on the corticospinal tracts - The circuit starts as output from the motor cortex is sent to the basal nuclei. The basal nuclei consider various courses of action and then select the best one. The best course of action is then sent to the thalamus and back to the motor cortex. The best solution can then be sent down the corticospinal tract.
Anatomy of the basal nuclei: 3 main parts
(a) Caudate nucleus
(b) Putamen
(c) Globus pallidus (externa and interna) -
Associated areas of the basal nuclei: 2 parts
(a) Substantia nigra (Pars compacta and Para reticularis)
(b) Subthalamic nuclei
Overall role of the basal nuclei in movement is to _____ or______.
reinforce, suppress
Involved in planning and programming voluntary movement; in essence, the basal nuclei ____ desired motor activity and ____ unwanted motor activity
reinforce, suppress
- together these two component form the striatum:
the caudate nucleus and putamen
Describe motor neural circuitry (a looping circuit)
short answer Motor cortex to Basal nuclei basal nuclei to thalamus Thalamus to motor cortex motor cortex to lower motor neurons
Describe motor neural circuitry (a looping circuit)
Input from the Motor areas of the cerebral cortex and the substantia nigra pars compacta (midbrain), this input enters the basal nuclei (in the caudate nucleus and putamen) and then follows the direct or indirect pathway. Output from the basal nuclei (either from the Globus pallidus pars interna or the Substantia nigra pars reticularis) is directed through the thalamus back to the cortex, completing the looping circuit -
There are two major pathways within the basal nuclei and associated nuclei
(a) Direct pathway: facilitates movement
(b) Indirect pathway: inhibits movement
For normal movement there should be a balance in the activities of the ____and ______pathways
direct and indirect pathways