410 Quiz#2 Flashcards
Components of BMP
- sodium, potassium, chloride, bicarbonate/CO2, BUN, creatinine and glucose
Factors Affecting GFR
- Age: GFR decreases with age
- Gender: GFR is lower in female
- Race: higher GFR used to be accepted in black patients
Gross Assessment of Urine
turbidity, Color, and smell
Urine Dipstick
- specific gravity: urince concentration
- pH: reflects serum pH
- RBCs
- protein: proteinuria = hallmark of renal disease
- glucose: when blood glucose > 180mg/dL
- Ketones: not normally in urine; byproduct of fat metabolism, uncontrolled DM
- bilirubin: conjugated bilirubin, screens for liver or bile duct disease
RBCs on urine Microscopy
- hematuria: >3RBCs per HPF
- gross color can be misleading
- transient vs persistent (persistent requires work-up)
- dysmorphia indicates glomerular disease
RBCs on urine Microscopy
- hematuria: >3RBCs per HPF
- gross color can be misleading
- transient vs persistent (persistent requires work-up)
- dysmorphia indicates glomerular disease
WBCs on urine microscopy
- Pyuria: >5 WBCs per HPF
- neutrophils: bacteria, renal TB, lithiasis
- Eosinophils: interstitial nephritis
Epithelial Cells on Urine Microscopy
- shed from genitourinary tract
- excess of epithelial cells may indicate contamination
- renal disease/tubular disease: >15 epithelial cells per 10HPF
Nitrates vs Nitrites
- Nitrate: normal constituent of urine; converts to nitrite in presence of certain bacteria
- Nitrites: abnormal, correlate well with possible infection; >10,000 bacteria count per mL
Leukocyte Esterase
enzyme produced by neutrophils, signals pyuria
subject to contaminated specimen, read only after 30-60 secs
nonspecific: TB, tumors, viral, stones, foreign bodies
works with synovial fluid as well to test for septic joint
Accuracy of hematuria, leukocytosis, and nitrites in urinalysis
- hematuria: very sensitive but not specific
- leukocytosis: very sensitive, not specific
- Nitries: not sensitive, very specific
Myocardial Cells
- “working cells” of the heart, contractile ability
- connected by intercalated discs with gap junctions
- held to by desmosomes
When Heart Cells are injured they release:
Troponin and CPK-MB
Anterior Leads
V1-V4
Lateral Leads
V5-V6, aVL, lead I
Inferior Leads
aVF, lead II, and lead III
Normal Intervals
PR: 0.12-0.20s
QRS: 0.06-0.11s
QT: 0.36-0.44s
ECG paper
small square: 0.04 s in duration, and 0.1mV in amplitude
P wave
- normal duration: 0.06-0.10s; Amplitude: 0.5-2.5mm
- if amplitude >2.5mm = RAE, P pulmonale
- if duration > 0.10s (2.5 boxes) = LAE, P mitrale
Flutter Waves
- seen instead of normal P waves when the atria fire rapidly from one site at a rate of 250-350bpm “Saw tooth pattern”
Fibrillatory Waves
seen instead of P waves when the atra fire rapidly from many sites at a rate of >350bpm
Short QRS complexes (in amplitude)
obesity, hypothyroid patients, pericardial effusion
1st degree AV heart block
when the PR interval is lengthened consistently due to a delay in impulse conduction through the AV node
2nd degree AV heart block
- PR intervals get progressively longer until a QRS complex is skipped and the cycle repeats
3rd degree AV heart block
P wave is completely independent from QRS complex, so PR interval cannot be measured
Wandering atrial pacemaker
- pacemaker changes location from site to site producing a slightly irregular rhythm
Paroxysmal Tachycardia
Normal rate that suddenly accelerates to a rapid rate producing an irregularity in the rhythm
Hypertrophy vs. Enlargement
-
Hypertrophy:
- thickening of the wall of the cardiac chamber due to increased pressure that the muscle is having to work against ( high BP, stenotic valve); common in ventricles
-
Enlargement (dilation):
- not the same as hypertrophy; often occurs due to stretching as a result of fluid overload; common in the atria
Clinical conditions associated with r atrial enlargement
pulmonic stenosis; tricuspid stenosis; tricuspid regurgitation
RAE criteria
R atrial enlargement: amplitude >2.5mm
- if P is biphasic, the initial component is taller than the terminal component
- leads II and V1 to diagnose atrial enlargement
LAE criteria
Left Atrial Enlargement: duration >0.10 sec (2.5 boxes)
- other criteria: terminal portion of P wave in V1 is negative, duration of >0.04 s and depth of >1mm
Right Ventricular Hypertrophy Criteria
less common, usually d/t pulmonary HTN or pulmonic stenosis, reverse R wave progression
criteria: RAD, R wave > S wave in V1 +/- S wave>R wave in V6
Left Ventricular Hypertrophy Criteria
- common causes: HTN and valvular disease, precordial leads more sensitive and helpful in diagnosing LVH
- Criteria (need ⅔): sum of the deepest S in V1/V2 + tallest R in V5/V5 > 35mm (Sokolov’s rule); R in lead I + S in lead III > 25mm; R in AVL >11mm;
Incomplete BBB
RR configuration (or “rabbit ears”) with normal QRS
RBBB criteria
- Criteria: prolonged QRS, M shaped RR’ (rabbit ears), wide S wave in lead I and V6
- seen in Coronary artery disease, and pulmonary embolism
LBBB Criteria
- Criteria: prolonged QRS, wide R wave in lead I and V6
Left Anterior Hemiblock
left axis deviation
normal QRS, tall R waves in lead I and deep S waves in aVF
Pre-Excitation Syndromes
-
Wolf-parkinson-white Syndrome
- accessory pathway: bundle of kent
- PR interval <0.12 seconds, wide QRS complex, Delta Wave
-
Lown-Ganong-Levine Syndrome
- accessory pathway: James Fibers
- PR interval <0.12seconds, normal QRS complex, absence of delta wave
Dissolvable Sutures
Vicryl, Dexon, Chromatic, PDS
Very dextrous Chris places dissolvable sutures
sizes, 2.0, 3.0, 4.0 (bigger # → smaller suture)
Non-Dissolvable Sutures
skin closure, drain anchors, internal suturing (sometime), vascular surgery (leave-in)
nylon, ethilon, silk, prolene
never eliminating stable Paul
size: 3.0, 4.0, 5.0
Needle Types
- cutting: skin
- non-cutting: tissue, bowel, vascular, skin
Removal Times of Sutures
- face/neck: 3-5 days
- scalp & arms: 7-10 days
- trunk/legs/hands/feet: 10-14 days
- Palms & soles: 14-21 days
Numbing the Wound
- Lidocaine 1% with epi: used on scalp & trunk, lasts longer, controls bleeding
- Lidocaine 1% without epi: penis, fingers, toes and nose
- Lidocaine: can be used locally at wound or as a digital block on toes and fingers (use small 25g needle)
Post-Suturing Wound Care
- toes/fingers: keep covered for 48-72 hours
- face/scalp: keep covered for 24-48 hours
- most wounds: keep covered for 18 hours
how late is too late for sutures?
face: 24-48 hours
everywhere else: 18 hours?
When to contact specialist for suturing?
nerve injury, arterial injury, any exposed bone, facial lacerations in children
Rouleaux formation
stacked RBCs in a linear distribution
Howell-Jolly Bodies
fragments of nucleus left over in RBCs
usually cleaned out by the spleen
Acanthocytes aka Spur Cells
irregular projections
caused by changes in lipid metabolism that affect the RBC membrane
Echinocytes aka Burr Cells
small blunt projections, uniformly spaced over the red cells, cells still have central pallor
caused by: liver disease, uremia
Schistocytes
helmet or egg shaped fragments
caused by hemolytic anemia
→indicates destruction of RBCs
MCH
mean corpuscular hgb
average hgb per RBC
MCHC
mean corpuscular hgb concentration
REDNESS
normochromic, hypochromic, hyperchromic
Fishbone for CBC
Procalcitonin
high serum procalcitonin can indicate a systemic bacterial infection and sepsis
STEMI or Injury Pattern
2 contiguous leads have 1.5-2mm ST elevation
NSTEMI or Ischemia (No Injury)
2 contiguous leads have 1+mm ST depression
unstable angina
chest pain at rest