4.1 - communicable diseases Flashcards

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1
Q

What are the categories of disease?

A
  • infectious
  • deficiency
  • inherited
  • mental disorder
  • social disease
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2
Q

What are communicable diseases?

A

Infectious diseases spread by pathogens
Pathogens include: bacteria (prokaryotes), viruses, fungi and protoctista.

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3
Q

What are the main communicable diseases?

A

Bacteria
Tuberculosis (TB), bacterial meningitis, ring rot (potatoes, tomatoes)
Virus
HIV/AIDS (human), Influenza (animals), Tobacco mosaic virus (plants)
Protoctista
Malaria, Potato/tomato late blight
Fungi
Black sigatoka (bananas), ringworm (cattle), athlete’s foot (humans)

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4
Q

What are the cycles of the virus?

A

lytic and lysogenic

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5
Q

What is a virus?

A

A non-living pathogenic small invading host cell

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6
Q

What is a virus that attacks bacteria?

A

bacteriophages, they take over the bacterial cell and use it to replicate as bacteria have a very fast rate of reproduction.

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7
Q

What is a bacteria?

A

Very small cells
Rapidly reproduce every 20 minutes
Release toxic waste products
Prokaryotic
no membrane-enclosed nucleus
carry out respiration but not in mitochondria or chloroplasts a single chromosome
a closed circle of double-stranded DNA with no associated histones
if flagella are present, they are made of a single filament of the protein flagellin
have smaller ribosomes than other groups

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8
Q

What is a protoctista?

A

Now widely known as protista
Eukaryotic with a wide variety of feeding mechanisms.
Protists that cause disease are parasitic that is they use a host to feed from.
May need a vector to transfer them to their hosts e.g malaria transferred to host by mosquito.

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9
Q

What is a fungi?

A

Eukaryotic
Most are multicellular organisms although the yeast that causes thrush is unicellular.
Not a major problem in humans but cause devastation in plants.
Digest their food externally before absorbing the nutrients (example of extracellular enzyme action).
Many fungi are saprophytes which means they feed on dead decaying material.
Have hyphae which can produce spores which allows them to spread rapidly through crops.

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10
Q

What is direct transmission?

A

passing a pathogen from host to new host with no intermediary

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11
Q

What is indirect transmission?

A

passing a pathogen from host to new host via a vector

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12
Q

Examples of direct transmission

A

Viruses – Hijack cellular machinery by inserting their genetic material into the host cell and then into the host DNA. The host cell then makes new copies of the virus which hen burst out of the cell destroying it and then spreading it to neighboring cells.
Protoctista – also take over cells and break them open. They simply digest the contents of the host cell and absorb the nutrients to reproduce.
Fungi – digest living cells and destroy them. The response of the body to the damage gives the symptoms of the disease.

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13
Q

Examples of indirect transmission

A

Bacteria – produce toxins that poison or damage the host cells in some way
break down cell membranes
inactivate enzymes
interfere with host genetic material and cell division
These toxins are a byproduct of the normal functioning of the bacterial cell.

Fungi – some produce toxins which affect host cells and cause disease.

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14
Q

what are the physical plant defenses?

A

cellulose cell wall
lignin thickening
waxy cuticle
bark
stomatal closure
callose in sieve tube
tylose in xylem

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15
Q

what are chemical plant defenses?

A

cell walls additional cellulose
callose deposition
oxidative bursts
increase in chemicals

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16
Q

what is cell necrosis?

A

cell suicide

17
Q

what are skin cells called?

A

keratinocytes

18
Q

what is the process of forming skin?

A

keratinocytes made at the base of the epidermis dry out and cytoplasm forms protein keratin - keratinisation

19
Q

what is the process of forming a clot?

A

clotting factors released when platelets bind to collagen start an enzyme cascade

20
Q

what happens during inflammation?

A

mast cells release histamines which signal for vasodilation and allows more permeability for white blood cells

21
Q

what are the 3 other primary defenses?

A

eyes have enzymes
ear canal is lined with wax
vagina has a mucus plug

22
Q

what are the two types of phagocytes?

A

neutrophils and macrophages

23
Q

What is the process of a neutrophil?

A

binds to opsonin attached to the antigen of the pathogen
endocytosis of pathogen forming a phagosome
lysosomes fuse to phagosome and release lytic enzymes
after digestion, harmless products can be absorbed.

24
Q

What is the process of a macrophage?

A

endocytosis of phagocyte but then becomes an antigen-presenting cell
these then interact with T and B lymphocytes

25
Q

what is the activation of B and T cells called?

A

clonal selection

26
Q

What are the 4 types of T cells?

A

T helper cells - releases cytokinins to B cells to trigger phagocytosis
T killer cells - attacks cells with foreign antigen
T memory cells - long term immunity
T regulator cells - stops process once pathogen is gone

27
Q

What do B lymphocytes differentiate into?

A

Plasma cells - release antibodies
B memory cells - act as immunological memory

28
Q

What are some examples of communications using cytokines?

A

macrophages release monkines that attract neutrophils by chemotaxis and active B cells

T cells and macrophages release inertleukins which stimulate clonal expansion

many cells release interferon which stimulates T killer cells

29
Q

what are the 3 antibody groups?

A

opsonins
Aggluntinins
Anti-toxins

30
Q

What do agglutinins do?

A

bind to two pathogens and clump them together - prevents normal functions and allows easy phagocytosis

31
Q

What do opsonin do?

A

bind to antigens on pathogen to allow easy phagocytosis

32
Q

what are the types of vaccinations

A

herd vaccinations - 95% population
ring vaccinations - vaccinating around the new virus