4 - Upper Extremities Mononeuropathies Flashcards
Mention the Shoulder Stabilizers ๐๐ Dr. Jamal
DYNAMIC STABELIZER
- Rotator cuff muscles
- Deltoid
- Scapular stabilizers (e.g., trapezius, serratus anterior)
- Long head of the biceps tendon
- Teres major
- Latissimus dorsi
STATIC STABELIZER
- Glenoid (shallow articular surface located on the lateral angle of the scapula)
- Labrum (fibrocartilaginous tissue within the glenoid cavity)
- Shoulder capsule (ligaments connect the humerus (the upper arm bone) to the glenoid (the shoulderโs socket) and stabilize the joint)
- Glenohumeral ligament (three ligaments on the anterior side of the glenohumeral joint)
Cuccurollo 4th Edition Chapter 4 MSK pg154
Medial vs Lateral Winging ๐๐ EXAM
Cuccurollo 4th Edition Chapter 5 EDX pg407
Root and Branch of Long Thoracic Nerve, EDX for shoulder winging & Treatment
๐ก C5, C6 and C7 spinal nerve root โ Long Thoracic Nerve
NCS of Motor Nerve
- SNAP: Not available
- CMAP: Abnormal
EMG
- Abnormal activity
- Serratus anterior with a long thoracic nerve injury
- Trapezius and SCM with spinal accessory nerve injury
Treatment of serratus anterior injury/injury to the long thoracic nerve
- Acute stage, pain reduction and ROM exercise
- Intermediate stage, passive stretching of the rhomboids, levator scapulae, and pectoralis minor
- Late stage, strengthening exercise of all shoulder girdle muscles, including the trapezius.
- Surgical repair with a dynamic muscle transfer in case of failed conservative treatment
Treatment of trapezius palsy/injury to the spinal accessory nerve
- Strengthen adjacent muscle groups, including rhomboids and levator scapulae.
Cuccurollo 4th Edition Chapter 5 EDX pg407
Describe the difference between a long thoracic nerve palsy and a C5โC6 radiculopathy ๐๐REVIEW
Long thoracic nerve palsy
Causes winging of the scapula with the arms outstretched because of weakness of the serratus anterior muscle.
C5โC6 radiculopathy
Shoulder and arm muscles (e.g., deltoid, biceps, supraspinatus) will remain normal.
Neurology Secrets 6th Edition Chapter 32 EDX pg472
If pt. cannot do abduction from 0-15; what nerve affected?๐๐ EXAM
Suprascapular nerve, supraspinatous muscle
Patient with right scapular fracture, now presents with difficulty with arm abduction initiation but full active range of motion. On examination normal sensory only weakness with ER and Abduction, no sensory findings.๐๐ EXAM
What muscles are affected?
What nerve is affected?
On EMG what location for the lesion is important to rule out.
Muscle
- Supraspinatous (Initial abduction)
- Infraspinatus (External rotation)
Nerve
- Suprascapular nerve
EMG
- Infraspinatous to rule out lesion in supascapular notch - ligament
My Answer
Origin of Suprascapular nerve
List 4 causes of suprascapular nerve palsy
EDX result of supracapular nerve entrapment
๐ก C5 and C6 spinal nerve roots โ upper trunk โ suprascapular nerve
Coarse
It runs through the suprascapular notch, which is covered by the transverse scapular ligament and branches to innervate the supraspinatus. The nerve then wraps around the spinoglenoid notch to innervate the infraspinatus
Causes
- Sports with repetitive overhead throwing/hitting volleyball
- Neuralgic amyotrophy (C5-C6)
- Spinal accessory nerve
- Axillary nerve
- Suprascapular nerve
- Long thoracic nerve
- Anterior interosseus nerve [AIN]
- Trauma like penetration injury
- Traction like stinger, Erbโs Palsy or rotator cuff tear
- Compression like entrapment or cyct or hematoms
Clinical Presentation
- Weakness in abduction (SS)
- External rotation (IS)
NCS
- SNAP not available
- CMAP: Abnormal
EMG:
- Abnormal activity in both SS and IS muscles (entrapment at suprascapular notch)
- Abnormal activity in IS only (entrapment is at the spinoglenoid notch)
Cuccurollo 4th Edition Chapter 5 EDX pg405-406
How is a suprascapular nerve lesion differentiated from a C5โC6 radiculopathy?
Suprascapular nerve lesion
- Preservation of the deltoid, biceps, and rhomboid muscles
- Abnormalities in the supraspinatus and infraspinatus muscles
A rotator cuff tear will show normal EMG of all the shoulder muscles
Neurology Secrets 6th Edition Chapter 32 EDX pg472
Devision of axillary nerve 3 marks
1- Anterior Branch
Supply Middle and anterior deltoid
2- Posterior Branch
Supplies Teres minor & Posterior deltoid
3- Superior lateral brachial cutaneous nerve (axillary sensory nerve)
Root and Coarse & Branches of Axillary nerve 4 marks
๐ก Teres major is supplied by Lower subscapular nerve (C5-C7) which branches from posterior cord BEFORE axillary nerve.
Root
- Upper trunk โ Posterior divisions & cord โ Axillary n. (C5-6)
Branch
- Deltoid
- Teres minor
- Superior lateral cutaneous n. of the arm
Cuccurollo 4th Eiditon Chapter 5 EDX pg404-405
Axillary nerve palsy Etiology, PEx & EDx.
Axillary nerve injury Presentation. 4 marks ๐๐
Etiology
- Traction or compression from a shoulder dislocation
- Humeral head fracture
- Improper axillary crutch use.
Clinical presentation
- Weakness of shoulder flexion
- Weakness of shoulder abduction (deltoid weakness)
- Weakness of shoulder external rotation (teres minor weakness).
- Abnormal sensation of the lateral shoulder (lat cut n. of arm)
NCS:
- SNAP not available
- CMAP: Abnormal
EMG:
- Abnormal activity in the deltoid & teres minor.
Cuccurollo 4th Edition Chapter 5 EDX pg405
Radial Nerve Origin & Coarse ๐๐ Motor and sensory branches.
ROOT
- C5-T1 โ upper, middle, and lower trunks โ posterior division & cord โ radial n.
COURSE
- Posterior to the axillary artery goes in between triceps.
- Long and medial heads of the triceps muscle toward the spiral groove
- Distally between the brachioradialis and brachialis
- Terminate in forearm as motor (PIN) and sensory (superficial) branch
ARM
-
Above Spiral Groove โ Muscles & Sensation Above Elbow
- Triceps brachii
- Anconeus
- Posterior cutaneous nerve of arm
- Lower lateral cutaneous nerve of arm
-
Below Spiral Groove โ Two Radialis & Sensation Below Elbow
- Brachioradialis (BR)
- Extensor Carpi Radialis Longus (ECR L)
- Posterior cutaneous nerve of the forearm
ELBOW
- Superficial radial sensory nerve
- Posterior Interosseus Nerve (PIN) ุนุตุจ ุงูู
ุดุงุจู
- Supinator
- Extensor Wrist Compartment ๐๐ EXAM Q
1st : Abductor pollicis longus (APL) + Extensor pollicis brevis (EPB)
2nd: Extensor carpi radialis brevis (ECR-B)
3rd: Extensor pollicis longus (EPL)
4th: Extensor digitorum communis (EDC) + Extensor indicis proprius (EIP)
5th: Extensor digiti minimi (EDM)
6th: Extensor carpi ulnaris (ECU)
Cuccurollo 4th Edition Chapter 5 EDX pg400-401
When to consider root injury in case of radial n. injury? 4 marks
๐ก In any EDX question, think neuro examination + EDX study result
Sensory
- Dermatomal sensory loss rather than peripheral nerve distribution
Motor
- Involvement of median or ulnar innervated C7 and C8 muscles
NCS
- Normal sensory study (SNAP)
EMG
- Involvement of cervical paraspinals
When to consider posterior cord injury or C7-8 radiculopathy in case of radial n. injury?
Posterior Cord (Plexopathy)
- Sensory loss around the deltoid muscle and upper arm.
- Weakness of the deltoid muscle +/- subscapular muscles
C7-8 Radiculopathy
- Involvement median (C5-T1) or ulnar n. (C8-T1)
- Involvement of cervical paraspinals (Neck pain)
Neurology Secrets 6th Edition Chapter 32 pg 472-473
What is the key muscle in differentiating a radial nerve palsy from a C7 radiculopathy? ๐๐
Flexor carpi radialis is a C7 muscle but is innervated by the median nerve.
Neurology Secrets 6th Edition Chapter 32 EDX pg472
How is a radial nerve palsy differentiated from a brachial plexus posterior cord lesion?
Lesion in the posterior cord of the brachial plexus, abnormal both
- Deltoid muscle (axillary nerve)
- Radial-innervated muscles
Radial nerve palsy
- Spared Deltoid muscle (axillary nerve)
- Affected Radial-innervated muscles
Neurology Secrets 6th Edition Chapter 32 EDX pg472
List 8 muscles innervated by Radial nerve ๐๐
List 3 Muscles functioning at the wrist joint which are innervated by radial n. ๐
List 4 Sensory branches of radial nerve ๐
Above the Elbow โExtensionโ
- Triceps
- Anconeus
At the Elbow โFlexionโ
- Brachioradialis
Below the Elbow โPIN, Extensionโ
- Supinator
- Abd. poll. longus
- Ext. poll. longus & brevis
- ECR longus & brevis
- Finger extensors
- ECU
Wrist Joint ู ุดุงุจู
- Extensor carpi radialis brevis (ECR-B)
- Extensor carpi ulnaris (ECU)
- Supinator
Sensory
- Posterior cutaneous n. of the arm
- Lower Lateral cutaneous n. of the arm
- Posterior cutaneous n. of the forearm
- Superficial radial sensory n.
Crutch Palsy: Injury - PEx - EDx. ๐๐
Injury
- Posterior cord of the brachial plexus, most commonly affecting the radial nerve.
Clinical presentation
- Weakness of deltoid muscles
- Weakness in all radial nerve innervated muscles, including the triceps brachii.
- Sensation will be decreased over the posterior arm, forearm and hands.
- Diminished triceps reflex (LMN)
EDXs
Posterior cords Injury
- Abnormal SNAPs and CMAPs of radial, axillary, and/or suprascapular nerves.
- Abnormal EMG activity in corresponding muscles
Isolated Radial Injury
- Abnormal radial SNAP and CMAPs
- Abnormal EMG activity in all radial nerve innervated muscles
Managment
๐ก External compression typically causes neurapraxia that recovers within 2 months.
- Remove compression: Discontinuing crutch use
- Static cock up splint or dynamic splinting
- No recovery within 8 to 10 weeks, surgical exploration is indicated
- No return of function after 1 year, refer for tendon transfer
Cuccurollo 4th Edition Chapter 5 EDX pg401
Radial entrapment at the upper arm vs elbow. How to distinguish in clinical examination. ๐๐ Hint: it neuro examination (sensory - motor - reflexes)
Above Spiral Groove โ Muscles & Sensation Above Elbow
- Triceps brachii
- Anconeus
- Posterior cutaneous nerve of arm
- Lower lateral cutaneous nerve of arm
Below Spiral Groove โ Two Radialis & Sensation Below Elbow
- Brachioradialis (BR)
- Extensor Carpi Radialis Longus & Brevis (ECR L & B)
- Posterior cutaneous nerve of the forearm
Elbow
- PIN
- Supinator
Radial entrapment at the upper arm vs elbow. How to distinguish in clinical examination. ๐๐ Saturday night palsy Etiology, PEx, EDx & Treatment.
Location
- Radial nerve injury at the spiral groove, compression, trauma or humeral fractures.
Etiology
- Humeral fractures
- Compression: Saturday night palsy or honeymoonerโs palsy.
- IM injection
- Iatrogenic injury (upper limb surgery)
Sensory
- Sensory deficits dorsal aspect of the hand and posterior forearm
- Intact sensation of posterior and lateral arm
Motor
- Preservation of elbow extension (triceps, anconeus)
- Weakness of elbow flexion (BR)
- Weakness of PIN muscles
- Weakness of supination (supinator)
- Wrist drop (ECR-L, ECR-B, ECU weakness)
- Weak finger extension (EDC weakness)
Reflexes
- Diminished brachioradialis reflex.
- Spared triceps and biceps reflexes
NCS
- Abnormal radial SNAPs and CMAP
- Normal triceps study
EMG
- Abnormal activity in all radial nerve innervated muscles below the spiral groove
- Normal triceps study
Cuccurollo 4th Edition Chapter 5 EDX pg401
Posterior Interosseous Nerve, Mention the motor and sensory supply. ๐๐ EXAM 2020
Motor ู ุดุงุจู
- Supinator muscle
- Extensor compartment of the wrist
Sensory
- Dorsal wrist joint capusle (proprioception)
- No cutaneous innervation
Last muscle to recover is the extensor indicis proprius.
List 5 radial muscles that are not innervated by PIN. ๐๐ Patient with elbow fracture, mention which radial muscles that are spared? ๐๐
- Triceps
- Anconeus
- Brachioradialis (BR)
- Extensor carpi radialis longus (ECR-L)
- Extensor carpi radialis brevis (ECR-B)
Radial tunnel syndrome (Brachial Family) Etiology, PEx & EDx.
Supinator Syndrome Etiology, PEx & EDx.
RADIAL TUNNEL SYNDROME
Etiology
- Entrapped radial n. between the brachialis and BR in the radial tunnel in the elbow.
PEx
- Lateral proximal forearm pain that worsens with activity
- approximately 3 to 4 cm distal to the lateral epicondyle.
- Can mimic lateral epicondylitis.
EDX
- NCS and needle EMG studies are typically normal
SUPINATOR SYNDROME (Lesion of the PIN)
Causes
- Compression of the nerve at the Arcade of Frohse
- Lipoma, ganglion cyst, synovitis from RA
- Monteggia fracture: fall on an outstretched hand with the forearm in pronation.
PEx (Pure Motor Syndrome, PIN is just like AIN of median nerve)
- Intact triceps
- Intact brachioradialis
- Intact radial deviation (ECR gets innervated before supinator muscle)
- +/- Supinator
- Wrist and finger drop (finger extensors and ECU)
- Intact sensory branches on arm & forearm
NCS
- Normal sensory radial nerve SNAP (itโs a motor syndrome)
- Abnormal radial CMAP motor study for PIN innervated muscles.
EMG
- Abnormal activity in the muscles innervated by the PIN
Cuccurollo 4th Edition Chapter 5 EDX pg402
How to different between lateral epicondylitis and radial tunnel syndrome? ๐๐
RADIAL TUNNEL SYNDROME
- Resisted extension of the third digit during elbow extension
- Resisted supination
- Palpation of the radial tunnel
LATERAL EPICONDYLITIS (TENNIS ELBOW)
- Palpation directly on the lateral epicondyle
- Cozenโs test: Pain on resisted wrist extension
- Less pain on resisted supination
Cuccurollo 4th Edition Chapter 5 EDX pg402
Wartenbergโs (Watch-enburg) Syndrome Etiology, PEx & EDx.
Etiology
- Superficial radial nerve injury at the wrist
- Seen in tight wristwatch, tight handcuffs, peripheral IV placement
Clinical presentation
- Pure sensory syndrome with no muscle involvement.
- Pure sensory syndrome with no muscle involvement
- Exacerbated with palmar and ulnar wrist flexion or forced pronation.
EDX
- NCS: Abnormal radial nerve SNAP but normal CMAP
- EMG: Normal
Cuccurollo 4th Edition Chapter 5 EDX pg403
List 4 Differential Diagnosis of a Wrist Drop ๐
Wrist drop: what are possible anatomic localizations? ๐๐
Differential Diagnosis of a Wrist Drop
- Mononeuropathy: PIN, radial nerve
- Radiculopathy: C6 or C7
- Diffuse polyneuropathy: Lead
- Plexopathy: Posterior cord, upper trunk, middle trunk
- Central: SCI/TBI/CVA, etc.
Cuccurollo 4th Edition Chapter 5 EDX pg402
Shapiro Chapter 24 Box 24.1
Other causes based on case, just to think in bigger picture:
- NMJ disorder
- Myopathies
Musculocutaneous Nerve: Origin and Branches of Musculocutaneous nerve.
Musculocutaneous nerve palsy Etiology, PEx & EDx
List 4 branches of Musculocutaneous nerve ๐๐
ORIGIN
- Upper trunk โ Anterior division โ lateral cord โ Musculocutaneous branch (C5-7)
BRANCHES
- Coracobrachialis
- Biceps brachii
- Brachialis (also radial n.)
- Lateral cutaneous nerve of the forearm
MUSCULOSURANEOUS PALSY
- Trauma: proximal humeral fractures, shoulder dislocation, gunshot wounds
- Compression
- Phlebotomy
PEx
- Elbow flexion weakness (Biceps, Brachialis)
- Coracobrachialis is typically spared
- Abnormal sensation over the lateral forearm.
NCS
- Abnormal SNAP in the lateral cutaneous nerve of the forearm
- Abnormal CMAP to the biceps brachii
EMG
- Abnormal activity in the brachialis and biceps brachii
Cuccurollo 4th Edition Chapter 5 EDX pg404
Median Nerve: Origin - Course
Motor & sensory branches of medial nerve. (11) ๐๐
Median innervated muscles in order, proximal to distal ๐๐
ORIGIN
- C5โT1 roots โ upper, middle, and lower trunks โ medial and lateral cords โ median n.
COURSE
- Medial to the axillary artery, It continues down the humerus.
- Ligament Of Struthers (LOS) at the medial epicondyle of the humerus.
FOREARM (4+1)
- Pronator teres (PT)
- FCR
- Palmaris longus
- Flexor digitorum superficialis (FDS)
- Palmar cutaneous (thenar eminence)
ANTERIOR INTEROSSEOUS NERVE (3)
- Flexor pollicis longus (FPL)
- Flexor digitorum profundus (1, 2)
- Pronator quadratus (PQ)
HAND (LOAF)
- Lumbricals (1, 2)
- Opponens pollicis
- Abductor pollicis brevis
- Flexor pollicis brevis 1/2
- Digital cutaneous n. for 3 1/2 fingers
SENSATION
- Sensation of the hand is lost in proximal lesions of median nerve, i.e. at the elbow
- Digital sensation will be lost in proximal lesions like carpal tunnel syndrome.
What are the common sites of median nerve compression should be considered in the deferential diagnosis of CTS? ๐๐
- Supracondylar ligament of Struthers
- Lacertus Fibrosis (Bicipital aponeurosis)
- Two heads of pronator teres
- Anterior interosseos branch (AIN)
- Carpal Tunnel
PMR Secrets 3rd Edition Chapter 18 Neuropathy pg156 Q19
A 40-year-old lady who works as a secretary, is complaining of numbness involving her right radial 3 and half digits that wakes her up at night. ๐๐
1) Name the nerve involved in this condition.
2) Name the root(s) origin of that nerve.
Female with radial aspect numbness, relived with shaking, increase at night.
1) Diagnosis
2) 3 Special Test
3) Other causes for her diagnosis ๐๐
Diagnosis
- Median nerve
- Carpal Carpal Tunnel Syndrom
- C5-T1
Tests
- Phalen
- Reverse Phalen
- Compression / Torniquete Test
- Tinelโs Sign
Causes
- Pregnancy (20%).
- Rheumatoid arthritis (any inflammatory arthritis).
- Fracture
- Acromegaly.
- Glucose (diabetes).
- Mechanical (overuse, occupational).
- Amyloid.
- Thyroid (myxedema)
- Infection (TB, fungal)
- Crystals (gout, pseudogout).
- Renal Failure
Cucurollo & Rheumatology Secrets
Ligament of Struthers & Bicipital aponeurosis (Lacertus fibrosus) Etiology, PEx & EDX.
Ligament of Struthers
The nerve becomes entrapped with the brachial artery under the ligament.
Bicipital aponeurosis
Thickening of the antebrachial fascia compressing median nerve or arterial blood gas or venipuncture injury.
Presentation
- Motor weakness
- Weakness in grip strength (FDP and FDS weakness)
- Wrist flexion (FCR weakness).
- Active benediction sign (proximal median nerve injury)
- Sensory loss
- Dull, achy sensation can occur in the distal forearm.
- Brachial pulse is possibly diminished.
NCS
- Abnormal median SNAP and CMAP
EMG
- Abnormal in median nerve-innervated muscles, including the PT
Cuccurollo 4th Edition Chapter 5 EDX pg391
Pronator teres syndrome Compression sites, PEx & EDX.
Compression site
- Two heads of the pronator teres (PT)
- Biceps aponeurosis.
- Sublimis Bridge: fascial band from the flexor digitorum superficialis (FDS)
Presentation
- Pronator Teres (PT) muscle is usually spared, as it receives its innervation before it is pierced by the nerve.
- Pain exacerbated by forceful pronation (PT) or finger flexion (FDS).
- Forearm and hand muscles may become easily fatigued.
- Patients present with pain and paresthesias in the first three fingers of the hand
NCS
- Abnormal median nerve SNAPs and CMAPs
EMG
- Abnormal activity in all median nerve innervated muscles EXCEPT the PT
Cuccurollo 4th Edition Chapter 5 EDX pg391
AIN palsy Etiology, PEx & EDX.
Etiology:
- Repetitive forearm flexion or pronation
- Elbow or forearm fractures
- Venipuncture or penetrating injuries
- Lacerations, or compression.
- Brachial neuritis.
Presentation
- Motor: Positive (abnormal) โOKโ sign and inability to form a fist (FPL, PQ, and FDP 1, 2)
- Sensory: volar branches to the wrist joint.
NCS
- Sensory Study (SNAP): Normal median nerve
- Motor Study (CMAP): Abnormal to the AIN muscles.
EMG
- Abnormal to the AIN muscles.
๐ก AIN is like PIN, both are motor nerves resulting in normal sensory study.
Treatment
- Surgical exploration and decompression should be delayed unless there is no recovery after 12 months.
Cuccurollo 4th Edition Chapter 5 EDX pg392
Content of carpel tunnel & Mention the boards. 10 marks ๐๐
Content
- Flexor digitorum superficialis tendons (4)
- Flexor digitorum profundus tendons (4)
- Flexor pollicis longus tendon (1)
- Median nerve (1)
Boarders
- Transverse carpal ligament & Carpal arch bones
Cuccurollo 4th Edition Chapter 5 EDX pg393 Figure 5-88
List 4 Risk Factors & 4 Symptoms for CTS ๐๐
Risk Factors
- Idiopathic process (most common)
- Increased canal volume โ thyroid disease, congestive heart failure (CHF), renal failure, mass (tumor, hematoma), and pregnancy
- Decreased canal volume โ fracture, arthritis, and rheumatoid tenosynovitis.
- Double crush syndrome โ diabetes mellitus, cervical radiculopathy, and TOS.
- Occupational exposures
- Female, Menopause
Symptoms
- Numbness of 3 1/2 fingers
- Thenar eminence will be spared as the palmar cutaneous branch comes off before the carpal tunnel (hyposthesia in pronator teres syndrom)
- Pain which can radiates to forearm (DDx cervical radiculopathy, epicondylitis)
- Muscle weakness in โLOAFโ muscles (opening jars, buttoning, or dropping objects.)
- Autonomic symptoms (tight or swollen feeling, temperature changes)
Cuccurollo 4th Edition Chapter 5 EDX pg393
Patient with numbness and pain in his thumb, index and middle finger. Give 6 DDx other than CTS. ๐
Spinal Cord
- C6 or C7 radiculopathy
- Cervical cord compression
- Myelopathy
- Syringomyelia
Brachial Plexus
- Brachial Plexopathy โ any trunk or mediolateral cord
- Thoraric outlet syndrom
Mononeuropathy
- Proximal median nerve injury (pronator or anterior interosseous syndrome)
- Martin-Gruber anastomosis (MGA)
MSK
- Tenosynovitis (De Quervainโs)
- Wrist tendonitis (overuse)
- Osteoarthritis (Carpometacarpal)
- Keinbockโs Disease (AVN lunate necrosis)
PMR Secrets 3rd Edition Chapter 18 Neuropathy pg155 Box 18-4
Mention which branches of median nerve that is not affected (spared) in CTS. 2 marks ๐๐
๐ก CTS = LOAF + Digit cutaneous nerve
1- Spared sensation of thenar eminence
Palmar cutaneous n. branches before the carpal tunnel
2- Spared AIN muscles
AIN branches before the carpal tunnel
3- Spared Forearm muscles
FCR, Palmaris longus and FDS
Patient with hand numbness suspecting CTS.
During your examination, what findings suggest other diagnosis rather than CTS?
What clinical findings suggest other pathology of his condition?
Findings make you suspect other diagnosis, not just CTS?
1- Tenderness
tendonitis, tenosynovitis
2- Involvement of more than LOAF muscles
- Weakness in other median innervated muscles โ AIN, PTS
- Weakness of ulnar or radial innervated muscles (root or plexus)
3- Reflexes
Asymmetry of muscle stretch reflexes or prominent neck pain. (root, UMN)
What are the degrees of CTS ๐๐
Memory Aid
Starts with sensory dysthesia at first, abnormal SNAP (demyelination)
Progress to weakness and atrophy of thenar (LOAF) muscles, abnormal CMAP (axonal)
Cuccurollo 4th Edition Chapter 5 EDX pg393
List 5 Provocative Tests for CTS ๐๐
1- Tinelโs sign
Percussion of the median nerve at the wrist
2- Phalenโs test
Hold the wrist at 90 degree flexion for approximately 1 minute
3- Reverse Phalenโs test
Hold the wrist at 90 degree of extension for approximately 1 minute
4- Tourniquet test
Inflated BP cuff reproduction of symptoms at 1 minute
5- Carpal compression test
Hold thumb compression over the tunnel for 30 seconds
Cuccurollo 4th Edition Chapter 5 EDX pg394
List 4 Ultrasound Findings in Carpal Tunnel Syndrome ๐
- Flattening & enlargement of the median nerve (inflamed and compressed)
- Decreased median nerve mobility with wrist flexion.
- Bowing of the flexor retinaculum (swelling & edema)
- Increased vascularity (Inflammation)
Role of EMG in CTS๐๐
๐ก Severe cases present with wasted hand and weakness due to axonal loss.
We do it with obvious wasted muscle patient, we want to:
- Confirm axonal loss affecting muscles bulk, thus confirming severity of CTS.
- Chronicity of the condition (Acute or chronic axonal injury)
Conservative Treatment for CTS๐๐
Controlling Risk Factors
1- Exacerbating activities, such as repetitive or excessive wrist flexion and extension and gripping, should be avoided
2- Ergonomic changes
The wrist should be splinted in 0 to 5 degrees of extension. Wrist splints are widely available but frequently hold the wrist in greater than 30 degrees of extension. In this case the patient should be instructed in reducing the wrist extension angle of the metal plate along the dorsum of the wrist.
3- Treat underlying medical disorders
Physiotherapy
- Physiotherapy: Passive Stretch & ROM Exercises
Orthosis
- Orthotics: Hand splint neutral to 30-degree extension
Pharmacological
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Diuretics
- Vitamin B6.
- Local corticosteroid injections
Cuccurollo 4th Edition Chapter 5 EDX pg395
List 6 Poor Prognosis for CTS ๐
๐ก Old female patient, lost sensation and weak motor power, waster hand and easily provoked, EDX shows demyelination and axonal lesion.
History (Chronic Severe CTS)
- Long duration >10 months in duration
- Constant paresthesias not improved by hand shakes
- Motor weakness
Examination
- Atrophy of thenar muscles
- Positive Phalenโs test in <10 seconds
EDX
- NCS: Prolonged latency
- EMG: Abnormal spontaneous activity (FIBs, PSW, CRD)
Cuccurollo 4th Edition Chapter 5 EDX pg395
Recovery time of CTS 2nd to pregnancy
It usually occurs at 6 months and resolves postpartum
What are the causes of false-positive result in CTS? ๐
- Cold temperature
- Increased age
- Increased height
- Increased hand circumference
PMR Secrets 3rd Edition Chapter 18 Neuropathy pg155 Box 18-4
List 3 EDX findings in Martin Gruber Anastomosis.๐๐
1- Falsely increased CV
2- Conduction block
Elbow median nerve CMAP > Wrist median nerve CMAP due to simultaneously stimulating the median and the ulnar nerve innervated muscles
3- Initial positive deflection of median nerve CMAP
Antecubital fossa stimulation resulting in volume conduction from ulnar nerve
Cuccurollo 4th edition Chapter 5 EDX pg395
Pt. with carpel tunnel operated, after 1 week came with swelling, stiffness, pain & dislocation. What you should exclude? Management? ๐๐ EXAM
DDx
- Tendon rupture (iatrogenic)
- Infection in operation site
- Nerve damage
- Necrosis
Management
- Xray
- Wrist U/S
- MRI
Ulnar Nerve Origin & Course ๐๐
Motor & sensory branches of ulnar nerve ๐๐
How can you differentiate sensory abnormalities in proximal vs distal ulnar nerve palsy? ๐๐
What branches before and after Guyon canal?
Origin
- C8โT1 Roots โ lower trunk โ medial cord โ ulnar nerve.
Course
- Medial surface of the medial head of the triceps runs in arcade of Struthers (AOS).
- Retrocondylar groove between medial epicondyle and olecranon
- Enters cubital tunnel โthick fascia made from FCRโ
- Through Guyonโs canal, it splits into three branches
- Superficial sensory branch
- Hypothenar branch
- Deep motor branch
Ulnar n. at Forearm / Before Guyon Canal / After Cubital Canal
- Flexor carpi ulnaris (FCU)
- FDP (third and fourth)
- Palmar ulnar cutaneous nerve
- Dorsal ulnar cutaneous (DUC) nerve
Ulnar n. at Wrist / After Guyon Canal
- Superficial sensory branch (digital nerves)
- Hypothenar branch (digiti minimi)
- Deep motor branch
- 2 Lumbricals
- 4 Dorsal interossei (โDABโ: Abduction)
- 3 Palmar interossei (โPADโ: Adduction)
- Palmaris brevis
- 1 Adductor pollicis
- 1/2 Flexor pollicis brevis (deep head)
Sensation
- Palmar ulnar cutaneous nerve (Abnormal in proximal compressions)
- Dorsal ulnar cutaneous (DUC) nerve (Abnormal in proximal compressions)
- Dorsal digital nerves (Travels through Guyonโs canal, abnormal in distal compression)
Cuccurollo 4th Edition Chapter 5 EDX pg396
What is the 1-1/2 Nerve supply of ulnar n.
Cuccurollo 4th Edition Chapter 5 EDX pg397
Mention the muscle and nerve supply of thumbs movements ๐๐
- Abduction โ Abductor Pollicis Longus by PIN branch of Radial, Brevis by Median.
- Adduction โ Adductor Pollicis by Ulnar (Froment Sign)
- Extenstion โ Extensor Pollicis by PIN branch of Radial
- Flexion โ Flexor Pollicis โ Longus by Median, Brevis by Median & Ulnar
- Opposition โ Opponens Pollicis by Median
List 6 causes of paresthesia in the little and ring fingers ๐๐
List 4 DDx in unlar neuropathy
- Cervical myelopathy & Syrinx
- C8-T1 Root Impingement
- Lower Trunk Plexopathy: apical lung tumour
- Medial Cord: clavicular fracture/ TOS
- Humeral Fracture
- Ulnar Nerve Entrapment at elbow
- Ulnar Nerve Entrapment at wrist
- Tendinopathies โ Tennis Elbow
Give 2 neuro-musculoskeletal causes for claw hand
NMSK
- Median and ulnar n. palsy (Lower trunk, Klumpkeโs Palsy)
- Thoracic Outlet Syndrome (Vascular)
- Charcot-Marie-Tooth Disease (Demyelination Polyneuropathy)
Ulner Claw
- Proximal ulnar neuropathy
Others
- Scarring dorsal hand burn
- Leprosy
Compare ulnar compression at the elbow and the wrist with respect to motor and sensory findings. ๐๐
ELBOW - CUBITAL TUNNEL SYNDROME
Sensory
- Abnormal dorsal ulnar cutaneous (DUC)
- Abnormal palmar ulnar cutaneous branch (PUC)
- Abnormal 4th-5th digital branches.
- Numbness in medial hand and fingers
Motor
- Weak grip & pinch
- Numbness in medial hand and fingers
- Abnormal flexor carpi ulnaris (FCU), flexor digitorum profundus (FDP) and all intrinsic muscles.
EDX
- Amplitude drop or conduction block across the elbow.
WRIST - GUYONโS CANAL SYNDROME
Sensory
- Numbness in 4th and 5th finger tip only
Motor
- Clawing of the ring and little finger
- Abnormal intrinsic hand muscles
Draw the ulnar nerve in the guyonโs canal & structures passing ๐๐ EXAM 2018-2019
Guyon canal
- Ulnar nerve
- Ulnar artery
Contains no tendons, which possibly explains why injuries to it are more likely related to external compression than overuse, as is seen in CTS
SHEAโS CLASSIFICATION SYSTEM
Type l: Involvement of the deep ulnar branch, hypothenar, and sensory
Type ll: Involvement of deep ulnar motor branches
Type lll: Involvement of the superficial ulnar sensory branch
Cuccurollo 4th Edition Chapter 5 EDX pg399
30-Year-Old Male presented with pain, numbness and tingling sensation in the 4th, 5th digits of the left arm of 2 monthsโ duration. How would you differentiate clinically if this is secondary to left C8-T1 Radiculopathy versus left ulnar entrapment neuropathy at the elbow or thoracic outlet impingement (TOS) (Neurogenic) ๐๐ MOCK
C8-T1 Radiculopathy (Radicular Pain)
- Neck pain with dermatomal distribution at C8-T1
Ulnar entrapment neuropathy
- Tenderness at left elbow, positive tinnelโs sign
Neurogenic TOS
- Left thumb abduction will be mainly affected
Arcade of struthers Etiology, Presentation, 2 Signs & EDX Finding.
Arcade of Struthers
- Fascial band in the medial arm that connects the brachialis to the triceps brachii
- Ulnar nerve can be injured due to compression under the fascial band.
Clinical presentation
๐ก Like playing arcade
- Involvement of all motor branches of ulnar n. (Distal โ Ulnar claw hand)
- Involvement of all sensory branches of ulnar n.
- Wrist flexion with a radial deviation (FCU weakness, unopposed action of FCR)
- Ulnar claw hand = Unopposed action of finger extensors affecting fingers pulley system leading to partial finger flexion of the fourth and fifth PIP and DIP and extension of MCP.
Examination
- Fromentโs sign: Inability to adduct the thumb (adductor pollicis weakness) leading to relaying on median innervated FPL muscle causing thumb flexion.
- Wartenbergโs sign: Inability to adduct the fifth digit (interossei weakness).
EDX
- Abnormal ulnar SNAP and CMAP
- Abnormal Dorsal ulnar cutaneous nerve SNAP (proximal injury)
- EMG: Abnormal activity in all the ulnar innervated muscles
Cuccurollo 4th Edition Chapter EDX pg397
Tardy ulnar nerve palsy Etiology, PEx & EDX.
๐ก Ulnar neuropathy that can occur months to years after a distal humeral fracture.
- Result from bone overgrowth or scar formation.
- Involvement of all the ulnar nerve innervated muscles.
- EDX findings: Abnormal ulnar SNAP and CMAP and abnormal EMG of all ulnar muscles
Cuccurollo 4th Ediiton Chapter 5 EDX pg398
Cubital Tunnel: Presentation - PEx - EDX - Treatment
Borders of Cubital Tunnel. 3 marks ๐๐
Cubital Tunnel
-
Put your index between medial epicondyle and olecranon
- Medially: Medial epicondyle of the humerus
- Laterally: Olecranon process of the ulna
- Top is UCL and FCU tendon or aponeurosis.
Etiology
- Compression beneath FCU aponeurosis or arcuate ligament.
Clinical presentation
๐ก Just like Pronator teres syndrome, sparing pronator muscles.
- The FCU may or may not be involved.
- All ulnar nerve innervated muscles
- Numbness 1/2 fourth digit and fifth digit
- Loss of dexterity and grip strength
PEx
๐ก FDP & FCU will be less affected since they branch in forearm
- Atrophy of hand muscles, esp 1st Dorsal Interosseous & Abductor Digiti Minimi
- โclawingโ of the hand due to intrinsic muscle weakness
- Positive Tinelโs sign at the elbow
EDX
- SNAP: Abnormal ulnar nerve and Dorsal ulnar cutaneous (DUC) findings
- CMAP: Decrease in CV and conduction block
- Abnormal activity in the ulnar nerve innervated (hand intrinsics > forearm) muscles
Treatment
- Patient education & lifestyle modification
- Avoid of strong, repetitive gripping โ avoid finger flexion
- Avoid repetitive elbow flexion โ limit nerve stretching
- Cushioning of the elbow to prevent compression โ avoid compression
Cuccurollo 4th Edition Chapter 5 EDX pg398
List 4 signs in Ulnar Neuropathy ๐๐
- Fromentโs Sign
- Wartenbergโs Sign (Weak interossie)
- Ulnar Claw Hand (Weak lumbricals +/- FDP)
- Static Benediction Sign
When do you suspect C8-T1 Root pathology in ulnar n. palsy patient?
๐ก Go back to basics: Any root (radiculopathy) comes with neck pain and other involvement of the major trunk or cords.
- History of neck pain
- Weakness of thumb flexion and abduction (Median n.)
- Weakness of index finger extension (Radial n.)
- Sensory loss of medial forearm
- UMN Finding (Abnormal Reflexes)
Shapiro Chapter 22 Table 22.1
List 6 Poor Prognosis for CTS ๐
History (Chronic Severe CTS)
- Long duration >10 months in duration
- Constant paresthesias not improved by hand shakes
- Motor weakness
Examination
- Atrophy of thenar muscles
- Positive Phalenโs test in <10 seconds
EDX
- NCS: Prolonged latency
- EMG: Abnormal spontaneous activity (FIBs, PSW, CRD)
Cuccurollo 4th Edition Chapter 5 EDX pg395