4 The breathless patient Flashcards

1
Q

Define breathlessness or DYSPNOEA

A
  • Dyspnoea, the sensation of feeling breathless, is a symptom experienced under conditions in which there is an inordinately high ventilatory demand relative to the ability to breathe, ‘air hunger’, and a heightened level of awareness of respiratory sensation and often a strong emotional component.

Its major physical sign is tachypnoea (abnormally rapid breathing)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What things to keep in mind when assessing the level of dyspnoea?

A

An important assessment is whether the dyspnoea is related only to exertion and how far the patient can walk at a normal pace on flat ground

Other clarifications:

  • variability in symptoms
  • good/bad days?
  • importantly; any times of day/night that are worse than others
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Discuss how one may encounter shortness of breath (SoB)

A

Can be caused by anything that reduces PaO2 or increases PaCO2

You can have issues with:

  • Ventilation - the amount of air brought into alveoli
  • Perfusion - the amount of blood brought to alveoli for gas exhange
  • Diffusion - (exchange surface) - defects include interstitial fibrosis, pulmonary oedema
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe the problems that may occur to an ideal gas exchange unit

A
  • Poor blood flow from the right side of the heart (clot)
  • Too much CO2
  • Abnormal tissue between alveolus and capillary (barrier to O2 transfer)
  • Anaemia (lack of Hb)
  • Faulty Hb (barrier to HbO2 complex)
  • Poor backflow to heart e.g. failing left ventricle (hence, blockage in pulmonary vein)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How to distinguish between respiratory and cardiovascular causes of SoB?

A

Can be done using patient history and examination

- It is based on taking full history + full examination, then selecting tests to rule differential diagnoses in or out

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe the various causes of dyspnoea

A
  • LVF or Mitral Stenosis: slow or sudden (pulmonary oedema); cause: increased pressure in pulmonary capillaries
  • Chronic bronchitis: chronic productive cough, with slowly progressive dyspnoea; Cause: excess mucus production
  • COPD: overdistention of airspaces distal to terminal bronchioles; slowly progressive with features of bronchitis, asthma, and emphysema leading to progressive dyspnoea
  • Asthma: problem with ventilation, (reversible airway disease - difficult to breathe out); acute episodes, separated by symptom-free breaks
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe congestive heart failure (CHF)

A

Definition: the heart fails when it is unable to eject blood delivered to it by the venous system

  • Blood builds behind the heart
  • Most common type is LHF (Left-sided heart failure)
  • In LHF, blood backs up in the lungs (pulmonary congestion)
    > LHF - pulmonary oedema (to raised hydrostatic forces in pulmonary vasculature)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

History taking (for breathlessness)

A
  • Age?
  • Onset of symptoms?
  • Variability?
  • Drug history
  • Occupation? Pets?
  • Associated symptoms?
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Describe orthopnoea

A

Defined as breathlessness on lying down.

  • While it is classically linked to heart failure, it is partly due to the weight of the abdominal contents pushing the diaphragm up into the thorax.
  • Such patients may also become breathless on bending over
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Describe the signs of breathlessness

A

Digital clubbing
- (can be due to lung cancer, bronchiectasis, pulmonary fibrosis, cyanotic heart disease)

  • Cyanosis
    > Central: reduced O2 saturation (>80%), blueish tongue and lips
    > Peripheral: bluing of extremities like fingers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe a physical examination you would to a patient suspected of breathlessness

A
  • Inspection
  • Palpation
  • Percussion
  • Auscultation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe what you may hear upon auscultation of a patient with suspected breathlessness

A
  • Wheeze: expiration, limitations of flow in asthma and COPD
  • Crackles: opening of closed bronchioles
    > Early inspiration associated with diffuse airflow limitation (e.g. bronchiolitis)
    > Late inspiration associated with pulmonary oedema, fibrosis, bronchiectasis
  • Pleural rub: inflammation of pleural surfaces
  • Stridor: high pitched breath sounds resulting from airflow through the obstructed airway
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

List some respiratory causes of breathlessness

A
  • Asthma (reversible)
  • COPD
  • Pneumonia
  • Lung cancer
  • Pneumothorax
  • Foreign bodies
    • most other respiratory diseases
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

List some cardiovascular causes of breathlessness

A
  • Heart failure: pulmonary oedema
  • Pulmonary embolism
  • Valvular disease
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

List some other causes of breathlessness

A
  • Functional breathlessness (e.g. obesity)
  • Anaemia (PaO2 and SaO2 are normal)
  • Anxiety
  • Thyroid Disease
  • Some muscle disorders
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Describe causes of hypoxemia

A
  • Decreased inspired pO2 [high altitude]
  • Respiratory acidosis, caused by CO2 retention in lungs, always produces a corresponding decrease in Alveolar pO2, which in turn decreases both PaO2 and Sa O2
    > Lots of causes of respiratory acidosis: depression of the medullary respiratory centre (barbiturates), paralysis of the diaphragm (e.g. amyotrophic lateral sclerosis), chronic bronchitis
  • Ventilation defect
  • Perfusion defect
17
Q

Describe how V/Q mismatch causes SOB, and why physiological compensation is limited

A
  • Ventilation (V) refers to the flow of air into and out of the alveoli
  • Perfusion (Q) refers to the flow of blood to alveolar capillaries
  • Normal V/Q ratio is 0.8
  • Changes to V/Q can lead to hypoxemia (decreases in PaO2 on ABG)

There are various mechanisms of hypoxemia:
- V/Q mismatch, right-to-left shunt, diffusion impairment hypoventilation, and low inspired pO2

18
Q

List some routine investigation for SOB:

A
  • Blood gas and pulse oximetry
  • Haematology (FBC)
  • Lung function testing (FEV1, FVC and FEV1:FVC)
  • Chest X-ray

Other tests:

  • Peak flow
  • High-resolution CT
  • More extensive lung function tests (gas transfer)
  • 6-minute walk/shuttle walk test
  • Sputum culture
  • Lung biopsy
  • Bronchoscopy
19
Q

Describe a blood gas and pulse oximetry test for breathlessness

A
  • Arterial blood gas monitoring: gives pH (normal 7.35-7.45), PaO2 (10.5 - 13.5kPa), and PaCO2 (5.1 - 5.6 kPa)
  • Pulse oximetry: Measures blood redness; normal blood oxygen saturation level should be >94%
20
Q

Describe haematology (FBC) tests for breathlessness

A

Important as if anaemia is the cause of SOB, saturations can show up normal

  • Haemoglobin (Hb)
  • Haematocrit
  • Mean corpuscular volume
21
Q

Describe lung function testing for breathlessness

A
  • FEV1: forced expiratory volume in 1 second
  • FVC - forced vital capacity: maximum amount of air a person can expel from the lungs after a maximum inhalation
  • FEV1/FVC: normal is >80%
22
Q

What is confirmation bias?

A

It is our tendency to cherry-pick information that confirms our existing beliefs or ideas

  • Confirmation bias is the tendency to acquire or evaluate new information in a way that is consistent with one’s pre-existing beliefs
23
Q

Overview of breathlessness in a clinic

A
  • Take a good history
  • Examine the patient
  • Analyse the information
  • Concept of differential diagnosis
  • Logical line of investigation and treatment