4 - STRUCTURE AND FUNCTIONS OF SYSTEMS Flashcards
what are the (4) main types of tissue?
epithelial (skin or internal organ covering)
connective (bone, cartilage, blood)
nervous
muscle
differentiate between negative and positive feedback
negative feedback: bringing conditions back to their normal or homeostatic function
positive feedback: an action that intensifies a condition so that it is driven further beyond its normal limits (e.g., labor contraction, lactation, or sexual orgasm)
how many lobes are in your right and left lung?
right lung: 3 lobes
left lung: 2 lobes
what is the membrane surrounding the lungs called? what are it’s 2 layers called?
pluerae, a membranous cover
inner layer: visceral pleura
- lines the lungs
outer layer: parietal pleura
- lines the chest cavity aka thoracic cavity
in between is the interpleural space
what is the diaphragm? what role does the diaphragm play?
a muscle that’s the lower border of the thoracic cavity. separates the thoracic cavity from the abdominal cavity
when you inhale, the diaphragm flats, allowing your chest cavity/lungs to expand
when you exhale, the diaphragm relaxes and pushes back upward which causes your chest and lungs to shrink in size, forcing air outward
what type of cell lines the respiratory tract? what do they do? where are these cells found?
respiratory epithelium
they produce mucus to moisten and protect our airways
the cells also have cilia which sweep away trapped pathogens and particles
found everywhere in the respiratory tract except the pharynx and larynx
list the structures of the respiratory tract in order
mouth/nose
pharynx
larynx
trachea
bronchi
bronchiole
alveoli
in the nose/mouth, what cell secretes mucus?
goblet cells (part of the respiratory epithelium)
what role does the pharynx play?
serves as the passageway for air and food (to the respiratory system and the digestive system)
what happens if a piece of food gets stuck in your windpipe?
the larynx will trigger the cough reflex to clear your airways
describe the structure of the trachea
a tube lined with c-shaped cartilage rings
what’s the epiglottis?
a structure covering the trachea, preventing solids/liquids from accidentally entering. when we breathe air, the epiglottis remains open so air can pass thru
what are alveoli? describe them
where gas exchange occurs between the respiratory and circulatory system
small, grape-like clusters
have a thin layer of cells, surrounded by capillaries. this layer serves as the interface between the respiratory system and the circulatory system
coated with surfactant, a liquid covering that reduces the surface tension, preventing H2O from collapsing the alveoli
what role does surfactant play in the respiratory system?
is a coating the covers alveoli, preventing it from collapsing as we inhale and exhale
what are the (2) major functions of the respiratory system?
internal respiration
external respiration
(both work together to get oxygen from the outside environment into our body’s cells and CO2 out our blood and exhaled)
differentiate between internal and external respiration
external respiration
- entry of air into lungs
- gas exchange between alveoli and blood (CO2 from blood to lungs to be exhaled; O2 from lungs to blood) – supplies blood with oxygen
internal respiration
- gas exchange between blood and cells (CO2 from cells to blood to be taken away to lungs; O2 from blood to cells) – supplies cells with oxygen
- intracellular respiration processes
how does gas exchange between the alveoli and the capillaries occur (in the respiratory system)
via simple diffusion (no transport proteins needed!!): gases like oxygen and carbon dioxide can simply diffuse across the thin alveoli membrane
how does CO2 move in the bloodstream? (how’s it transported?)
considered bulk flow!!: volumes of fluid move from an area of higher pressure in a capillary bed to an area of lower pressure in the tissues via filtration
primarily transported in the plasma, the liquid portion of blood in the form of bicarbonate (HCO3-)
most CO2 in the blood gets combined with water to form carbonic acid which then dissolved into bicarbonate and H+ ions. this reaction is catalyzed by enzyme, carbonic anhydrase. it occurs in red blood cells
can also be transported as it is (CO2). it can mix directly with the plasma as a gas or can bind with hemoglobin inside of the RBCs, forming carbaminohemoglobin
how does oxygen move in the bloodstream? (how’s it transported?)
primarily transported in the blood via hemoglobin
this is considered bulk flow: volumes of fluid move from an area of higher pressure in a capillary bed to an area of lower pressure in the tissues via filtration.
how do gases in the blood get to the cells of our body?
oxygen will be unloaded by the hemoglobin and diffuse out of the red blood cells across the thin walls of our blood vessels thru any interstitial fluid, finally entering the cell by diffusing across their membrane
CO2 follows the opposite path. it diffuses out of the cell, across the membrane, thru the interstitial fluids, and across the blood vessel walls where they can be transported by red blood cells as bicarbonate
what part of the brain controls respiration? what does it do specifically and how?
medulla oblongata
makes sure you’re always breathing, whether it’s conscious or unconscious
will also adjust breathing rate depending on oxygen needs of the body. this is done thru chemoreceptors which monitor levels of certain chemicals in the blood. the medulla specifically looks for H+ ions in the bloodstream. this is because when CO2 is transported in the blood, the process produced H+ ions. so when there’s lots of CO2, there will be lots of H+ ions. the medulla will signal the diaphragm contract so oxygen can be brought in and then CO2 exhaled.
some chemoreceptors also looks at concentrations of oxygen and CO2
an increase in H+ or CO2 will cause an increase in breathing rate. High blood oxygen partial pressure would cause a decrease in breathing rate.
how are fish able to survive and get oxygen without being exposed directly to air?
gills are highly folded surfaces that provide a large surface area across which gas exchange can occur
to get oxygen from the water, fish use something called countercurrent exchange. as a fish swims thru water, water flows over the gills in the opposite direction of the blood that is flowing thru the fish. as the water and blood flow past one another, the oxygen that is dissolved in the water, diffuses into the bloodstream, replenishing the oxygen levels in the fish’s blood
this process occurs many times due to the large surface area which is how fish are able to survive from the oxygen gained from the countercurrent exchange
countercurrent exchange maximizes diffusion of oxygen into the blood and carbon dioxide into water
why do fish die when they’re taken out of water?
water helps keep their gills separated, maintaining the large surface area
when removed from the water, their gills collapse onto one another, reducing the surface area. leads to death due to insufficient oxygen intake
** FISH DO NOT HAVE LUNGS!!
describe hemoglobin
a protein that functions to transport oxygen in our bloodstream
has 4 polypeptide subunits. each of these subunits contain an Iron (Fe) atom which is critical to the function as Iron is what binds to the oxygen
describe cooperativity in hemoglobins
in cooperativity, a molecule has multiple binding sites. when oxygen binds to one site, it increases the affinity for the next oxygen to bind.
so, each oxygen that binds makes it easier for the next one to bind
note that hemoglobin can bind up to 4 oxygens (1 for each iron atom)
the reverse is true as well! when you remove an oxygen from hemoglobin, it becomes easier for the next oxygen to come off
what is myoglobin?
used to transport oxygen to and from the cell in muscles
equivalent of hemoglobin
has a different binding affinity from hemoglobin
describe the structure of hemoglobin
has 4 heme groups: each with an iron atom in the centre surrounded by a porphyrin ring. the iron is able to form up to 6 bonds, one of which is to the oxygen
note that heme is a prosthetic group (a non protein, iron, attached to a protein)
what does it mean when the oxygen-hemoglobin association curve has been shifted to the right?
leads to reduced affinity between oxygen and the hemoglobin. hemoglobin will release oxygen more easily – due to increased oxygen demands, the hemoglobin will be less stingy!
so, a left shift means increased affinity. hemoglobin will hold onto oxygen more tightly. this is when cells have less oxygen need
what (5) factors causes the oxygen-hemoglobin association curve to shift right? describe these factors
“CADET - face right”, an increase in the following will cause the curve to shift right
CO2: an increase in CO2 = an increase in cellular respiration = oxygen being used up and supply needs to be replenished
Acid: increased CO2 levels = more acid = hemoglobin is more likely to release oxygen due to conformational change induced by increased acidity (acidic = low pH). this conformational change will preferentially bind to CO2
2,3 DPG: a metabolite that gets consumed whenever oxygen is present. but if oxygen isn’t present, 2,3 DPG builds up so it’s presence indicates lack of oxygen in tissue
Exercise: it consumes oxygen and produces CO2 during its process
Temperature: high temp = high metabolic rate = consuming more oxygen and cells will demand more of it than usual
define thermoregulation
control of exchange of heat with the environment
differentiate between ectotherms and endotherms
ectotherms (COLD-BLOODED)
- obtain body heat from the environment
- include invertebrates, amphibians, reptiles, and fish
endotherms (WARM-BLOODED)
- generate their own body heat and have a much higher basal metabolic rate (BMR) than ectotherms
what are cnidaria?
includes soft-bodied stinging animals such as corals, sea anemones, and jellyfish
how does respiration work in cnidaria?
direct with the environment!!
have large surface areas and every cell is either exposed to the environment or close to it → simple diffusion of gases directly with outside environment
(flatworms and some small animals also exhibit this type of respiration)
what are annelids?
include earthworms, polychaete worms, and leeches
members of the group are to some extent segmented, in other words, made up of segments that are formed by subdivisions that partially transect the body cavity
how does respiration work in annelids?
mucus secreted by earthworms provides a moist surface for gaseous exchange via diffusion
the circulatory system brings oxygen to cells, and waste products back to the skin for excretion
what are arthropods?
includes such familiar forms as lobsters, crabs, spiders, mites, insects, centipedes, and millipedes.
distinguishing feature of arthropods is the presence of a jointed skeletal covering composed of chitin (a complex sugar) bound to protein
how does respiration work in arthropods?
series of chitin-lined respiratory tubules called trachea that open to the surface via openings called spiracles, through
which oxygen enters and carbon dioxide exits
oxygen carriers such as hemoglobin are not needed due to the direct distribution and removal of respiratory gases between the air and body cells
the moistened tracheal endings ease the rate of diffusion
DIFFERENT FOR SPIDERS: they have book lungs that are stacks of flattened membranes enclosed in internal chambers
describe the structure of lungs
these are invaginated structures made of two sub-portions: the left lung and right lung
the left lung is smaller and consists of 2 lobes, while the right lung is made of 3 lobes
left lung is smaller to accommodate the heart, which is also on the left side of the chest
lungs have a membranous cover known as the pleurae, which have two pleura layers: the visceral and parietal pleura. the space in between these two layers is the intrapleural space