4. Pain Management Flashcards
When should be be evaluated and documented
every appointment
What considerations should be kept in mind when deciding what pain management meds should be used
- Individual patient/familt
- Extent of treatment
- Duration of procedure
- Psychological factors
- Medical history/ physiologic factors (bleeding disorders, liver, and kidney problems)
What are the first line drug therapy for pre and post op pain
non-opiod analgesics (esp. NSAIDs)
Which have anti-inflammatory properties
- Tylenol
- Motrin
- Codeine
- Advil
Motrin and advil (also ibprophen)– only NSAIDs
Why should caution be used with opiods
respiratory depression- most common cause of death with opiod use
Properties of NSAIDs
Antipyretic
Anti-inflammatory
Analgesic
Dosing for children less than 12 (ibprofen)
4-10 mg/kg/dose every 6-8 hrs
Max= 40 mg/kg/24 hrs
Dosing for children >12 Ibprofen
200 mg every 4-6 hrs
Max=1.2g/24 hr
Dosing for adult ibprofen
200-400mg every 4-6 hr
Max=1.2 g/24hr
MOA of NSAIDs
- Inhibition of COX (cyclooxygenase) enzymes
- Prevents the formation of prostaglandins
Caution should be used with NSAIDs in what patients
- GI disease
- Bleeding disorders (affects platelet aggregation- increases bleeding time)
- Impaired renal function
Why is aspirin avoided in kids
linked to reye’s syndrome
Properties of acetaminophen
antipyretic and analgesic
Dosing for tylenol in kids <12
10-15 mg/kg every 4-6hr
Max= 90mg/kg/24 hr – not exceeded 2.6g/24hr
Dosing for tylenol in kids <12
325-650mg every 4-6 hr or 1000mg 3-4 times a day
Max= 4g/24hrs
MOA of tylenol
not fully understood (thought to act through COX inhibition
T/F Caution should be taken when using tylenol in kids with bleeding disorders
F- tylenol doesn’t disrubte platelet aggregation and clotting time
OD of tylenol can lead to
acute liver failure
Name the metabolic substrate that causes acetaminophen toxicity
NAPQI
When detoxifies NAPQI
glutithione
What is the antidote for tylenol OD and how does it work
NAC (N-acetylcysteine) acts by bumping up glutithione
Initial symptoms of acetaminophen toxicity are
- Nausea
- Vomiting
- Drowsniness
- Lethargy
- Malaise
progression of tylenol toxicity can lead to
- Upper right quadrant pain
- Tachycardia
- Hypotension
- Hepatic disfunction
- Multi-organ failure
Look at chart on slide 11
ok