4. Nuclear medicine

Question 1

Physiological degenerative changes on bone scintigraphy

Answer 1

slightly increased focal tracer uptake in spine, shoulder joints and sternoclavicular joint

Question 2

What is normal thyroid scintigraphy?

Answer 2

• normal size gland with homogenous uptake
• no focal lesion

Question 3

How does diffuse toxic goiter appear on thyroid scintigraphy?

Answer 3

• diffused toxic goiter (Grave’s disease) appears enlarged with increased uptake
• no focal lesions within the lobes

Question 4

How does a cold nodule appear on thyroid scintigraphy?

Answer 4

• focal uptake is decreased in one or both thyroid glands
• could be caused by cyst, inflammation or thyroid cancer

Question 5

How does a solitary toxic nodule appear on thyroid scintigraphy?

Answer 5

intensive focal uptake in one thyroid lobe with rest of the gland suppressed

Question 6

What is ischemic heart disease?

Answer 6

atherosclerotic narrowing of coronary arteries leading to reduction in perfusion at stress

Question 7

What is myocardial perfusion scintigraphy?

Answer 7

• investigation of relative perfusion distribution
• radiopharmaceutical uptake in the myocardium is proportional to the blood flow

Question 8

What is PET-CT’s significance?

Answer 8

• CT is for the morphology
• PET is the assess the FDG uptake and detect any lesions