4. MHC Flashcards

1
Q

Vilka celler uttrycker MHC-I och MHC-II? Vilka antigen presenteras?

A

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2
Q

Hur processas de två typerna av antigen? Korspresentation?

A

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3
Q

Hur får vi den stora MHC-variabiliteten inom arten?

A

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4
Q

Varför är 25% av syskon HLA-identiska?

A

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5
Q

Vad heter människans MHC-I-molekyler? MHC-II? Vad är TAP, LMP, invariant chain?

A

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6
Q

Vad är beta-2-mikroglobulin?

A

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7
Q

Vilka delar formar triaden med MHC-II? MHC-I?

A

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8
Q

Kan kroppsegna peptider finnas i MHC-molkylerna?

A

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9
Q

Vad menas med MHC-restriktion?

A

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10
Q

Hur nedärvs MHC från föräldrarna?

A

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11
Q

OBS! Skillnad mellan antikroppsvariabilitet (individnivå, pga DNA-rekombination hos individen)
och MHC-variabilitet (pga väldigt många olika MHC-gener inom arten)!

A

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