4. Growth in Childhood Flashcards
1
Q
When is the fastest phase of growth?
A
Antenatal
2
Q
What are the causes of short stature?
A
Genetic Pubertal and growth delay IUGR/SGA Dysmorphic syndromes Endocrine disorders (hypothyroidism, GH deficiency, steroid excess) Chronic paediatric disease Psychosocial depravation
3
Q
What are the possible causes of abnormal growth despite normal hormones?
A
Turner Syndrome
Down syndrome
Skeletal dysplasias
4
Q
Name some chronic paediatric diseases.
A
Asthma Sickle cell Juvenile chronic arthritis IBD (Crohns, coeliac) Cystic fibrosis Renal failure Congenital heart disease
5
Q
What are some causes of tall stature?
A
Tall parents
Early puberty
Marfan syndrome and others
Growth hormone excess
6
Q
Name 3 syndromes associated with obesity.
A
Cushings
Prader Willi
Lawrence Moon
7
Q
Name 5 monogenic obesity syndromes.
A
Leptin deficiency Leptin receptor deficiency POMC deficiency PC-1 deficiency (Proprotein convertase) MC4R deficiency
