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Basic Science and clinical embryology > 4. Gamete Interaction > Flashcards

4. Gamete Interaction Flashcards

1
Q

Release of cortical granule

A. Is the first morphological indication of oocyte activation
B. Does not involve Ca2+ release
C. Occur after the extrusion of first PB
D. Occurs few hours after sperm penetration

A

A. Is the first morphological indication of oocyte activation

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2
Q

Nucleolar precursor bodies are site of

A. Centrometic DNA Synthesis
B. Protein synthesis
C. RNA synthesis
D. None of the above

A

D. None of the above

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3
Q

The maturation promoting factor (MPF) is

A. cAMP
B. p34cdc2
C. A complex of p34cdc2 and cyclin B
D. Cyclin B

A

C. A complex of p34cdc2 and cyclin B

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4
Q

When does oocyte activation begin

A. Sperm binding to zona pellucida
B. Sperm attach to the inner and outer membrane
C. Sperm entry into an oocyte
D. Sperm in contact with cumulus oophorus

A

C. Sperm entry into an oocyte

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5
Q

Sequence of sperm transport

A. Testist -> Epididymis -> Rate testis -> Urethra
B. Seminiferous tubule -> Rate testis -> Epididymis -> Vas deferens
C. Seminiferous tubule -> Epididymis -> Rate testis -> Urethra
D. Testis -> Ductus deferent -> Vas deferent -> Epididymis

A

B. Seminiferous tubule -> Rate testis -> Epididymis -> Vas deferens

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6
Q

Acrosome reaction in capacitated spermatozoa involve

A. Release of enzyme proacrosin, acrosin, hyaluronidase, and other enzymes
B. Release of enzyme proacrosin and acrosin
C. Fusion of inner and outer acrosomal membrane
D. Hyperactivation movement of the sperm

A

A. Release of enzyme proacrosin, acrosin, hyaluronidase, and other enzymes

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7
Q

The protein semenogelin 1 is produced by

A. The prostate
B. The testis
C. Seminal vesicle
D. Bulbourethral gland

A

C. Seminal vesicle

more detail

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8
Q

Hyperactivation of the sperm is seen

A. At the time of sperm binding to zona
B. After sperm penetrate through the zona
C. After acrosome reaction
D. In culture medium under physiologic pH and temperature

A

D. In culture medium under physiologic pH and temperature

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9
Q

The role of uterus and Fallopian tube in sperm activation is

A. Capacitation
B. Capacitation and acrosome reaction
C. Providing glucose for sperm motility
D. None of the above

A

A. Capacitation

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10
Q

Sperm penetration into the oocyte requires

A. Release of cortical granules
B. The acrosome reaction
C. Zona hardening
D. Decondensation

A

B. The acrosome reaction

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11
Q

Human semen is derived from the

A. Testes
B. Testes and Prostate
C. Testes and Seminal Vesicle
D. Testes, Prostate, and Seminal Vesicle

A

D. Testes, Prostate, and Seminal Vesicle

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12
Q

When does acrosome reaction occurs (more than 1 correct answers possible)

A. During sperm-zona binding
B. While the sperm is advancing through the cumulus cell
C. When the sperm is in contact with the cervix
D. Inside the fallopian tube
E. After removal of seminal plasma in vitro

A

A. During sperm-zona binding
B. While the sperm is advancing through the cumulus cell

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13
Q

The place for sperm storage before ejaculation

A. Testis
B. Epididymis
C. Vas deferens
D. Seminiferous tubules

A

B. Epididymis

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14
Q

What causes COC activation?

A. High HCO3-
B. High Ca2+
C. High cAMP
D. High Amphiregulin (AREG)

A

B. High Ca2+

COC :

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15
Q

Mature spermatozoa are produced during

A. Spermatogenesis
B. Spermatocytosis
C. Spermiogenesis
D. None of the above

A

C. Spermiogenesis

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16
Q

Immotile sperm and immotile cilia are feature of

A. Kartagener’s syndrome
B. Beckwidth-Widerman syndrome
C. Kallman’s syndrome
D. Disorders involving mitocondria DNA deletion

A

A. Kartagener’s syndrome

More detail

17
Q

What maintains 1st meiotic arrest in oocytes?

A. Ca2+ level
B. High level of cAMP
C. Decreased level of cAMP
D. Cyclin C

A

B. High level of cAMP

18
Q

In human, centrioles in the embryo is derived from

A. Mother only
B. Father only
C. Contribution by both father and mother
D. None of the above

A

B. Father only

19
Q

What is TRUE concerning centrioles in the human spermatozoa?

A. Only the proximal centriole remains
B. Only the distal centriole remain
C. Both proximal and distal centrioles remain intact
D. Both proximal and distal centrioles disappear

A

A. Only the proximal centriole remains

Basic Science and clinical embryology (1 decks)

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