4 Embryo Development of Heart Flashcards

1
Q

parts of bulbus cordis

A

conus cordis truncus arteriosus

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2
Q

aortic sac

A

ascending aorta

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3
Q

truncus arteriosus

A

roots & pulmonary portions of aorta and pulmonary trunk

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4
Q

conus cordis

A

outflow tracts of ventricles

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5
Q

proximal segment of bulbus cordis

A

right ventricle

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6
Q

primordial ventricle

A

left ventricle

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7
Q

primordial atrium

A

left and right auricles & trabeculated portions of the atria

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8
Q

right horn of sinus venosus

A

sinus venarum (smooth-walled portion of R atrium)

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9
Q

left horn of sinus venosus

A

coronary sinus

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10
Q

primordial pulmonary v + its branches

A

smooth-walled portion of left atrium

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11
Q

In what week does heart development begin?

A

Week 3. Solid, then canalizes at Week 4.

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12
Q

Tissue responsible when heart begins to form?

A

Cardiogenic mesoderm form solid, horseshoe-shaped endothelial cord.

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13
Q

What creates primitive heart tube?

A

Lateral body folding (ventrally and medially, to approach midline).

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14
Q

How does head folding reposition heart and pericardial cavity? Before head fold

A

Rostral to oropharyngeal membrane Ventral to pericardial cavity

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15
Q

How does head folding reposition heart and pericardial cavity? After head fold

A

Caudal to oropharyngeal membrane Dorsal to pericardial cavity Ventral to the foregut Rostral to the septum transversum/diaphragm

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16
Q

Fate of dorsal mesocardium?

A

Degenerates to transverse pericardial sinus

17
Q

What day does heart beat begin?

A

Day 22 or 23

18
Q

When does heart folding occur?

19
Q

Describe how folding heart tube creates cardiac loop.

A

Cranial: CRV caudally, right, ventrally Caudal: DS dorsally, superiorly

20
Q

Circulation through primordial heart!

21
Q

VSD

A

Ventricular septal defect Most common Membranous portion of IV septum fails to form.

22
Q

Transposition of great vessels

A

Aorticopulmonary septum grows straight instead of spiraling

23
Q

Tetralogy of Fallot

A

Aorticopulmonary septum divides outflow tract unequally. INTERnational: VSD H: hypertrophy of right ventricle O: overriding aorta PancakeS: pulmonary stenosis

24
Q

atrioventricular septum

A

Endothelial cells revert to mesenchymal state. Endocardial cushions fuse. Divide atrioventricular canal into R + L AV canals.

25
interatrial septum
fusion of septum primum and septum secundum
26
Blood flow before and after birth.
Before: R to L atrium through foramen ovale. After: Foramen ovale becomes fossa ovalis (valve of foramen ovale against septum secundum due to high pressure in L atrium)
27
interventricular septum
membranous portion from mesenchyme of endocardial cushion tissue.
28
aorticopulmonary septum
Endocardial cushions throughout conus cordis and truncus arteriosus. Later fuses inferiorly with membranous IV septum
29
Outflow tract
Pulmonary trunk (right ventricle) Aorta (left ventricle)
30
Smooth portions of R and L atrium
R: sinus venorum, from right horn of sinus venosus L: pulmonary veins
31
ID structure. Derivative? Divided by?
truncus arteriosus --\> pulmonary trunk & ascending aorta divided by aorticopulmonary (spirling) septum
32
ID opening.
foramen ovale (oval foramen)