4 Embryo Development of Heart Flashcards
parts of bulbus cordis
conus cordis truncus arteriosus
aortic sac
ascending aorta
truncus arteriosus
roots & pulmonary portions of aorta and pulmonary trunk
conus cordis
outflow tracts of ventricles
proximal segment of bulbus cordis
right ventricle
primordial ventricle
left ventricle
primordial atrium
left and right auricles & trabeculated portions of the atria
right horn of sinus venosus
sinus venarum (smooth-walled portion of R atrium)
left horn of sinus venosus
coronary sinus
primordial pulmonary v + its branches
smooth-walled portion of left atrium
In what week does heart development begin?
Week 3. Solid, then canalizes at Week 4.
Tissue responsible when heart begins to form?
Cardiogenic mesoderm form solid, horseshoe-shaped endothelial cord.
What creates primitive heart tube?
Lateral body folding (ventrally and medially, to approach midline).
How does head folding reposition heart and pericardial cavity? Before head fold
Rostral to oropharyngeal membrane Ventral to pericardial cavity
How does head folding reposition heart and pericardial cavity? After head fold
Caudal to oropharyngeal membrane Dorsal to pericardial cavity Ventral to the foregut Rostral to the septum transversum/diaphragm
Fate of dorsal mesocardium?
Degenerates to transverse pericardial sinus
What day does heart beat begin?
Day 22 or 23
When does heart folding occur?
Day 22-28
Describe how folding heart tube creates cardiac loop.
Cranial: CRV caudally, right, ventrally Caudal: DS dorsally, superiorly
Circulation through primordial heart!
Yay! :)
VSD
Ventricular septal defect Most common Membranous portion of IV septum fails to form.
Transposition of great vessels
Aorticopulmonary septum grows straight instead of spiraling
Tetralogy of Fallot
Aorticopulmonary septum divides outflow tract unequally. INTERnational: VSD H: hypertrophy of right ventricle O: overriding aorta PancakeS: pulmonary stenosis
atrioventricular septum
Endothelial cells revert to mesenchymal state. Endocardial cushions fuse. Divide atrioventricular canal into R + L AV canals.

