4 Embryo Development of Heart Flashcards

1
Q

parts of bulbus cordis

A

conus cordis truncus arteriosus

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2
Q

aortic sac

A

ascending aorta

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3
Q

truncus arteriosus

A

roots & pulmonary portions of aorta and pulmonary trunk

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4
Q

conus cordis

A

outflow tracts of ventricles

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5
Q

proximal segment of bulbus cordis

A

right ventricle

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6
Q

primordial ventricle

A

left ventricle

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7
Q

primordial atrium

A

left and right auricles & trabeculated portions of the atria

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8
Q

right horn of sinus venosus

A

sinus venarum (smooth-walled portion of R atrium)

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9
Q

left horn of sinus venosus

A

coronary sinus

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10
Q

primordial pulmonary v + its branches

A

smooth-walled portion of left atrium

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11
Q

In what week does heart development begin?

A

Week 3. Solid, then canalizes at Week 4.

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12
Q

Tissue responsible when heart begins to form?

A

Cardiogenic mesoderm form solid, horseshoe-shaped endothelial cord.

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13
Q

What creates primitive heart tube?

A

Lateral body folding (ventrally and medially, to approach midline).

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14
Q

How does head folding reposition heart and pericardial cavity? Before head fold

A

Rostral to oropharyngeal membrane Ventral to pericardial cavity

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15
Q

How does head folding reposition heart and pericardial cavity? After head fold

A

Caudal to oropharyngeal membrane Dorsal to pericardial cavity Ventral to the foregut Rostral to the septum transversum/diaphragm

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16
Q

Fate of dorsal mesocardium?

A

Degenerates to transverse pericardial sinus

17
Q

What day does heart beat begin?

A

Day 22 or 23

18
Q

When does heart folding occur?

A

Day 22-28

19
Q

Describe how folding heart tube creates cardiac loop.

A

Cranial: CRV caudally, right, ventrally Caudal: DS dorsally, superiorly

20
Q

Circulation through primordial heart!

A

Yay! :)

21
Q

VSD

A

Ventricular septal defect Most common Membranous portion of IV septum fails to form.

22
Q

Transposition of great vessels

A

Aorticopulmonary septum grows straight instead of spiraling

23
Q

Tetralogy of Fallot

A

Aorticopulmonary septum divides outflow tract unequally. INTERnational: VSD H: hypertrophy of right ventricle O: overriding aorta PancakeS: pulmonary stenosis

24
Q

atrioventricular septum

A

Endothelial cells revert to mesenchymal state. Endocardial cushions fuse. Divide atrioventricular canal into R + L AV canals.

25
Q

interatrial septum

A

fusion of septum primum and septum secundum

26
Q

Blood flow before and after birth.

A

Before: R to L atrium through foramen ovale. After: Foramen ovale becomes fossa ovalis (valve of foramen ovale against septum secundum due to high pressure in L atrium)

27
Q

interventricular septum

A

membranous portion from mesenchyme of endocardial cushion tissue.

28
Q

aorticopulmonary septum

A

Endocardial cushions throughout conus cordis and truncus arteriosus. Later fuses inferiorly with membranous IV septum

29
Q

Outflow tract

A

Pulmonary trunk (right ventricle) Aorta (left ventricle)

30
Q

Smooth portions of R and L atrium

A

R: sinus venorum, from right horn of sinus venosus L: pulmonary veins

31
Q

ID structure.

Derivative?

Divided by?

A

truncus arteriosus

–> pulmonary trunk & ascending aorta

divided by aorticopulmonary (spirling) septum

32
Q

ID opening.

A

foramen ovale (oval foramen)