4 Deformation Analysis Flashcards
What are the definitions of displacement and velocity?
Displacement is the distance of movement of the myocardium.
Velocity is the speed of movement of the myocardium.
What are the definitions of strain and strain rate?
Strain is the change in length as a percentage.
Strain = (change in length) / (original length) x 100
Strain rate is the speed at which the strain occurs
Average strain rate = strain / time
What do positive and negative strain indicate?
Positive strain is relaxation (lengthening).
Negative strain is contraction (shortening).
Therefore, negative strain values are used to assess ventricular systolic function.
How is myocardial deformation assessed?
The regional LV function is assessed by measuring the contractility, the ability of the region of the LV to develop a force, which causes the muscle to deform (shorten or lengthen) and move (velocity). The contractility is assessed by measuring the deformation and velocity. The myocardial displacement is assessed with strain. The myocardial velocity is assessed with TDI.
The contractility is dependent on the preload (the level of ventricular stretch, which is dependent on ventricular filling) and afterload (the force the heart works against to eject blood).
What is the coordinate system in myocardial deformation analysis?
Displacement or velocity or strain is measured via a coordinate system. The coordinate system axes are longitudinal (the long axis of the ventricle), radial (the short axis of the ventricle) and circumferential.
What are longitudinal, radial, circumferential and axial strain?
Longitudinal strain measures the change in length.
Radial strain measures the change in diameter.
Circumferential strain measures the change in circumference along the short axis of the heart.
Axial strain is the movement in relation to the probe.
Displacement = velocity x time.
How are longitudinal and axial strain measured?
Longitudinal strain assesses deformation, measured using speckle echocardiography.
Axial strain assesses deformation, measured using TDI.
What are the definitions of shear deformation and shear strain?
Shear deformation is the distortion of the heart when layers of the myocardium slide over each other due to the twisting and untwisting of the heart. Shear deformation, unlike strain, involves a change in the shape of the myocardium without a change in the volume.
Shear strain is the relative displacement, and the change in the angle, between the layers of the myocardium.
What is torsion?
Torsion is the twisting of the heart, during systole, and untwisting, during diastole. Torsion causes shear stress within the layers of the myocardium. Torsion allows effective ejection and filling.
Torsion is the difference in rotation between the basal and apical, normalised to the distance between the base and the apex, measured in degrees/cm. Normal LV torsion is 10-20°/cm. LV torsion may be increased in HCM but may be decreased in HF.
How do the apex and the base rotate during systole and diastole?
In systole, the heart twists due to the helical organisation of the myocardial fibres in the LV. The apex rotates clockwise and the base rotates anticlockwise whilst the mid-LV stays stationary. This is measured in degrees. LV twist is assessed by acquiring apical and basal short axis slices.
What is the myocardial velocity gradient and how is it calculated?
MVG is the rate of change in velocity within the myocardium. MVG shows the difference in velocity between two positions in the myocardium over time.
MVG= ∆velocity/∆time
How is TDI derived strain calculated?
The TDI derived strain rate is calculated using the velocities at two positions in the myocardium. Integrating the TDI derived strain rate over time results in the TDI derived strain.
How is TDI derived strain accuracy improved via controls?
Decrease the sample volume size to increase the spatial resolution. This improves tracking which improves strain measurements.
Decrease the offset distance (the distance between the sample volume and the endocardium).
How is TDI derived strain accuracy improved via algorithms?
Spatial averaging and temporal averaging are the averaging of the velocity over space and time. This decreases noise to improve signal quality but removes potentially important variations in velocity, and therefore strain.
Sample volume tracking uses tracking algorithms (e.g. speckle tracking) to track the myocardium to improve the accuracy of strain measurements.
Drift compensation corrects for the shifts in the baseline during TDI acquisition via processing algorithms. Drift is the deviation in the baseline due to small tracking and alignment errors.
What are the limitations of TDI derived strain?
Angle dependence, the ability of the movement of other structures to affect the movement of the myocardium, segmental variation, poor image quality and artefact and inter-operator variation.