#4 BIOPSY

Question 1

bios came from greek word?

Answer 1

life

Question 2

opsy came from greek word?

Answer 2

look/appearance

Question 3

It is the excision and examination of tissue from a living subject for diagnostic purposes

Answer 3

Biopsy

Question 4

What is the preferred site to perform biopsy?

Answer 4

at the periphery of the tumor

Question 5

Careful handling of the tissue is mandatory for?

Answer 5

sarcoma and lymphoma

Question 6

T or F: Biopsy could be therapeutic

Answer 6

True

Question 7

They introduced surgical biopsy as an essential tool for diagnosis in Berlin on year ____

Answer 7

1870, Ruge and Joham Vert

Question 8

He put forward an argument that confirmations should be made before surgeries for malignancies on year ____?

Answer 8

1889, Emarch

Question 9

He 1st introduced this principle (Biopsy) in US

Answer 9

William Halsted

Question 10

What year is the study of exfoliated cells from a female genital tract by Papanicolau (papsmear)?

Answer 10

1941

Question 11

Why was biopsy adapted?

Answer 11

to study cells from other body systems

Question 12

The indication for biopsy includes a lesion that persist with no apparent etiologic basis for?

Answer 12

more than 2 weeks

Question 13

The indication for biopsy includes a inflammatory lesion that does not respond to local treatment after?

Answer 13

10 to 14 days

Question 14

The indication for biopsy includes a persistent ________ changes in surfaces tissue

Answer 14

hyperkeratotic

Question 15

it is a condition due to excess keratin that harden and thicken the outer layer of skin

Answer 15

Hyperkeratosis

Question 16

The indication for biopsy includes any persistent _________ that is visible or palpable beneath normal tissue

Answer 16

Tumescence or swelling

Question 17

Indication of biopsy includes __________ and __________ of tissue rejection after transplant on kidney and liver

Answer 17

Evaluation and monitoring

Question 18

What are the types of biopsy?

Answer 18

1. Exfoliative cytology
2. Excisional biopsy
3. Incisional biopsy
4. Aspiration/needle biopsy
5. Bite biopsy
6. Cutaneous biopsy
7. Punch biopsy
8. Shave biopsy
9. Wedge biopsy

Question 19

Now widely used for diagnosis of malignant conditions susch as cervix, vagina, uterus, bronchial, urine and CSF and in fluid aspirated from pleural and peritoneal cavities.

Answer 19

Exfoliative Cytology

Question 20

Smears are made from expected metastasis, desquamated cells, desquamated cells, sex hormonal status in females, sex chromatin phenotype

Answer 20

Exfoliative cytology

Question 21

Refer to the shedding of dead skin cells from the outermost layer of the skin

Answer 21

Desquamated cells

Question 22

What is the standardized fixative for exfoliative smear?

Answer 22

95% ethanol

Question 23

the complete removal of lesion and most reliable biopsy, this permits pathologist to examine all of the suspicious tissue.

Answer 23

Excisional biopsy

Question 24

Excisional biopsy may be done for unfixed sample and is immediate diagnosis using?

Answer 24

frozen section–cryostat

Question 25

The cryostat has a temperature of? and a procedure time of?

Answer 25

-18 to -20C 15 to 20 mins

Question 26

**removal of part of the lesion** for histological examination

Answer 26

Incisional biopsy

Question 27

preferred for **large situated tumors that cannot be excised** to make sure it is not benign, therefore small pieces only

Answer 27

Incisional biopsy

Question 28

What is the shape of incision in incisional biopsy?

Answer 28

Ellipse/Elliptical

Question 29

Use of needle and syringe to penetrate a lesion for aspiration

Answer 29

Aspiration/needle biopsy

Question 30

To do aspiration/needle biopsy, infiltrate site with local anesthesia then place a needle attached to a syringe with what sizes?

Answer 30

22G needle attached to a 10 ml syringe

Question 31

Aspiration/needle biopsy is fixed using what fixative?

Answer 31

95% ethanol

Question 32

Biopsy in which small pieces of tumor are removed with **special forceps**

Answer 32

Bite biopsy

Question 33

What is the example of bite biopsy?

Answer 33

Endoscopic biopsy

Question 34

Type of biopsy removed from the skin lesion

Answer 34

cutaneous biopsy

Question 35

The gross lesion assessment of this biopsy is very limited and is **larger than 2 millimeter**

Answer 35

Punch biopsy

Question 36

Punch biopsy is stained with?

Answer 36

H&E

Question 37

biopsy that is always **present orientation problems** and reserve for secretions requiring only histopathologic diagnostic

Answer 37

Shave biopsy

Question 38

Shave biopsy uses what process to obtain specimen?

Answer 38

Curettage

Question 39

Specimen is subdivided with a **razor blade** with a size thicker than 3 to 4 mm

Answer 39

Wedge biopsy

Question 40

WEDGE BIOPSY: spx size: ____ ; if EM ____

Answer 40

**thicker than 3-4 mm**; less than **1mm thin**

Question 41

biopsy that refers to excisional or shell out and is a procedure in which the lesion is **not entered but removed**

Answer 41

Marginal excision

Question 42

Give the sites for exfoliative cytology?

Answer 42

Cervix, uterus, vagina, bronchial, arpirated fluid from pleural and peritoneal cavities

Question 43

Give a biopsy that is obtained from skin

Answer 43

Cutaneous and punch biopsy