3.8.2.1 Stem Cells (Unit 8 Gene Expression) Flashcards

1
Q

What does totipotency mean?

A

can specialise into any type of cell including placenta, found in early stages of an embryo

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2
Q

What does pluripotency mean?

A

can specialise into most types of cells, but not form placenta, found in early embryos but not the earliest

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3
Q

What does multipotency mean?

A

can form some types of cells e.g. red and white blood cells, found in adult mammals

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4
Q

What does unipotency mean?

A

can only form one type of cell, found in adults

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5
Q

Cells that can specialise into any type of cell including placenta, found in early stages of an embryo are called…

A

Totipotent

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6
Q

Cells that can specialise into most types of cells, but not form placenta, found in early embryos but not the earliest are called…

A

Pluripotent

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7
Q

Cells that can can form some types of cells e.g. red and white blood cells, found in adult mammals are called…

A

Multipotent

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8
Q

Cells that can only form one type of cell, found in adults are called…

A

Unipotent

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9
Q

multicellular organisms are made up from…

A

many different types of specialised cells

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10
Q

specialised cells originated from..

A

stem cells

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11
Q

unspecialised cells that can develop into other cell types are called

A

stem cells

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12
Q

Two main sources of stem cells can be found..

A

in the embryo, adult tissues

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13
Q

these types of stem cells are only present in mammals in the first few divisions of the embryo

A

totipotent (very early embryo)

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14
Q

these types of stem cells are still found in the embryo but have lost their ability to develop into differentiate into placental cells

A

pluripotent

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15
Q

adult stem cells can be one of two types

A
  1. multipotent stem cells

2. unipotent stem cells

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16
Q

These types of stem cells can only differentiate into ONE type of cell

17
Q

these types of stem cells can differentiate into a limited number of stem cells e.g. bone marrow cells can form RBC and WBC

A

multipotent stem cells

18
Q

Stem cells specialise because…

A

different genes are expressed (turned off and on)

19
Q

Stem cells all contain the same genes - true or false?

20
Q

Specialised cells all look different - why?

A

they all express different genes and thus proteins - this determines the cells overall structure

21
Q

Which stem cell can red blood cells originate from?

A

bone marrow stem cells

22
Q

Transcription is when

A

DNA is copied into mRNA

23
Q

Translation is when

A

mRNA is translated into a sequence of amino acids

24
Q

what are cardiomyocytes?

A

heart cells

25
what can stem cells be used for?
treat diseases e.g. paralysis - replace damaged cells/tissues
26
benefits of using stem cells in medicine?
save life and improve quality of life for many people
27
iPS cells stands for?
induced pluripotent stem cells
28
What are iPS cells?
created in the lab - reprogramming adult stem cells to become pluripotent
29
What are the limitations with adult stem cells?
limited differentiation capacity - they are mulitpotent
30
Where do we source embryonic stem cells from?
embryos created in the lab from IVF
31
Embryonic stem cells are classified as one of twp types
1. totipotent (very early embryo) | 2. pluripotent (early embryo)
32
Issue surrounding embryonic stem cells?
1. ethics surrounding the sourcing of the embryos (embryo will be destroyed)
33
In all cells which genes will be permanently expressed?
Housekeeping genes e.g. genes involved in respiration
34
All organisms develop from a fertilised egg - what is the scientific name for this?
zygote
35
Zygotes divide by what process?
Mitosis