3.8.1 Flashcards
What are mutations?
A change to the base sequence of DNA
Caused by errors during DNA replication
Rate of mutation can be increased by mutagenic agents
What is a substitution mutation?
One or more bases are swapped for another
What is a deletion mutation?
One or more bases are removed
What is an addition mutation?
One or more bases are added
What is a duplication mutation?
One or more bases are repeated
What is an inversion mutation?
A sequence of bases is reversed
What is translocation ?
A sequence of bases is moved from one location in the genome to another
What is frameshift?
Entire amino acid sequence will be different
What are mutagenic agents?
Increase the rate of mutations
UV radiation, ionising radiation, some chemicals, some viruses
How do mutagenic agents work?
Act as a base
Alter bases
Change the structure of DNA