37- Principle of Antimicrobial Chemotherapy Flashcards
1
Q
What is the main principle of antimicrobial chemo selective toxicity therapy?
A
To eradicate neoplastic cells or pathogenic organism.
2
Q
How does the principle of selective toxicity work?
A
It inhibits the function of cancer cells/pathogens while preserving the host cell function
3
Q
What is an antibiotic substance?
A
It is a substance produced by one microbe that inhibits the growth or viability of other microbes
4
Q
What were the first substances used as potential antimicrobials?
A
Bacterial stains
5
Q
What were the first systemic antibacterial agents?
A
Sulfonamides- and are highly plasma protein bound.