37- Principle of Antimicrobial Chemotherapy Flashcards

1
Q

What is the main principle of antimicrobial chemo selective toxicity therapy?

A

To eradicate neoplastic cells or pathogenic organism.

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2
Q

How does the principle of selective toxicity work?

A

It inhibits the function of cancer cells/pathogens while preserving the host cell function

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3
Q

What is an antibiotic substance?

A

It is a substance produced by one microbe that inhibits the growth or viability of other microbes

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4
Q

What were the first substances used as potential antimicrobials?

A

Bacterial stains

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5
Q

What were the first systemic antibacterial agents?

A

Sulfonamides- and are highly plasma protein bound.

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