3.6.1.2 - Receptors Flashcards

1
Q

Where does the central nervous system receive information from it external and internal environment?

A

receptors

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2
Q

What is the pacinian corpuscle?

A
  • a receptor that responds to changes in mechanical pressure
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3
Q

What are features of all receptors (demonstrated by pacinian corpuscle?

A
  • Only respond to a specific type of stimulus
    ( pacinian corpuscle only responds to mechanical pressure. )
  • Stimulation of a receptor leads to the establishment of a generator potential
    > by acting as a transducer - convert the change in form of energy by the stimulus into a nerve impulse/ generator potential
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4
Q

what is the function of the pacinian corpuscle?

A
  • transduces the mechanical energy of the stimulus (eg: pressure) into a generator potential
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5
Q

where is the pacinian corpuscle found?

A
  • occur deep in the skin
  • most abundant on fingers, soles of feet, external genetalia
  • also occur in joints/ligaments/tendons
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6
Q

describe the basic structure of a pacinian corpuscle

A
  • sensory neurone ( axon to ending
  • surrounded by layers of connective tissue - viscous gel between
  • surrounded by blood capillary
  • surrounded by capsule
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7
Q

What is the type of sodium channel in the plasma membrane of the sensory neurone at the centre of the pacinian corpuscle?

A
  • stretch - mediated sodium channel
    > permeability to sodium changes when they are deformed (eg: by stretching)
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8
Q

Describe how the pacinian corpuscle functions…

A
  • in its resting state, the stretch-mediated sodium channels of the plasma membrane around the neurone of a pacinian corpuscle are too narrow to allow sodium ions to pass along them
    > pacinian corpuscle is at resting potential
  • when pressure is applied to pacinian corpuscle it is deformed and the plasma membrane around its neurone becomes stretched
  • stretching widens stretch-mediated sodium channels on plasma membrane allowing sodium ions to diffuse into the neurone (greater pressure causes more sodium channels to open - more sodiums ions enter)
  • influx of sodium ions changes the potential of the plasma membrane and it becomes depolarised
    > produces a generator potential
  • if generator potential reaches threshold it creates an action potential (nerve impulse) that passes along the neurone, via other neurones to central nervous system.
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9
Q

where are light receptor cells of the mammalian eye found?

A

retina (the inner most layer of eye)

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10
Q

What are the two main types of light receptor cells?

A
  • rod cells
  • cone cells
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11
Q

How do light receptors act as transducers?

A
  • convert light energy into the electrical energy of a nerve impulse
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12
Q

Explain what the Pacinian corpuscle illustrates

A

● Receptors respond only to specific stimuli
○ Pacinian corpuscle only responds to mechanical pressure

● Stimulation of a receptor leads to the establishment of a generator potential
○ When threshold is reached, action potential sent (all-or-nothing principle)

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13
Q

Explain the differences in sensitivity to light for rods & cones in the retina

A

> Rods are more sensitive to light
● Several rods connected to a single neurone
● Spatial summation to reach / overcome threshold (as enough
neurotransmitter released) to generate an action potential

> Cones are less sensitive to light
● Each cone connected to a
single neurone
● No spatial summation

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14
Q

Explain the differences in visual acuity for rods & cones in the retina

A

> Rods give lower visual acuity
● Several rods connected to a single neurone
● So several rods send a single set of impulses
to brain (so can’t distinguish between
separate sources of light)

> Cones give higher visual acuity
● Each cone connected to a single neurone
● Cones send separate (sets of) impulses to brain
(so can distinguish between 2 separate sources
of light)

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15
Q

Explain the differences in sensitivity to colour for rods & cones in the retina

A

> Rods allow
monochromatic vision
● 1 type of rod / 1
pigment

> Cones allow colour vision
● 3 types of cones - red-, green- and blue-sensitive
● With different optical pigments → absorb different wavelengths
● Stimulating different combinations of cones gives range of colour perception

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