3.6/3.7 Proteins Flashcards
What is the protein structure consisted of?
one or more polypeptide chains folded in a 3D shape
What is the primary structure of a protein?
Order of amino acids determined by genetic code
What is the secondary structure of proteins?
alpha helix coil or beta pleated sheet
What is the tertiary structure of proteins?
how a protein is further folded (globular shape - 3D)
What is the quaternary structure?
more than one polypeptide chain, held together by bonds
Where are hydrogen bonds formed?
they are formed between R groups, and are numerous and easily broken
Where are disulphide bonds together?
formed between sulphur containing amino acids - found in skin/hair
What are the properties of globular proteins?
Proteins rolled into a ball are globular, they are are soluble, used in metabolism and as enzymes.
What are the main components of an alpha helix?
- Hydrogen bonds form between oxygen and hydrogen molecules brought into close proximity
- Help to stabilise a structure
What are the main components of a beta pleated sheet?
- folds back upon itself many times forming anti-parallel chains
- forms hydrogen bonds
- stability
What are hydrogen bonds?
Hydrogen and oxygen atoms from both the main chain and the R group may form hydrogen bonds
What are Disulphide Bridges?
The R groups of two amino acids contain sulphur atoms, when in close proximity, form disulphide bridges
What are Ionic bonds?
Many of the carboxylic acid and amino groups form charged groups in solution, oppositely charged groups form ionic bonds
What are Hydrophobic interactions AKA covalent bonds?
many hydrophobic R groups tend to cluster towards the interior of the protein molecule forming hydrophobic interactions
What are proteins?
- proteins can be enzymes, hormones and oxygen transporters (i.e. haemoglobin),
- 3D complex microscopic molecules,
- polymers called polypeptides
- made up of amino acid units