3.5 Flashcards
Sympathetic activity
“Normal” activity
Targeted homeostatic mechanisms
Sweating boi
Sympathetic activation
Activation of entire sympathetic system
Parasympathetic activity
Pupil constriction
Nicotinic receptors
Ach binding->
Sodium channels open->
Depolarization (excitatory)
E.g adrenal medullae
Muscarinic
Ach binding->
G protein activation->
Activation/inhibition of effector cell via secondary messengers
E.g: increase gland secretion, decrease cardiac muscle activity
Alpha 1 receptors
Bind to NE or E
stimulate ca release from ER
Usually excitatory
Alpha 2 receptors
Decrease cAMP levels
Usually inhibitory
Beta receptors
Bind to NE or E
increase cAMP levels in target cell
Beta 1
Excitatory
E.g increased cardiac contraction
Beta 2
Smooth muscle relaxation
E.g respiratory smooth muscle relaxation
Beta 3
Stimulates lipolysis in adipocytes
Dual innervation
Gas vs brake
Negative feedback
Single innervation
Positive feed back loops
Autonomic receptors
Baroreceptors- pressure
Chemoreceptors- responds to chemicals
Cerebral cortex
Fear, anxiety, arousal
