3.4 The Cells of the Nervous System and Neurotransmitters at Synapses Flashcards

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1
Q

Describe the structure of a neuron.

A

Neuron structure involves dendrites, cell body and axon.

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2
Q

Dendrites

A

These are the parts of a neuron that receive a stimulus and conduct an electrical impulse to the cell body.

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3
Q

Cell body

A

This is the part of a neuron that contains the nucleus. The cell body connects the dendrites which receive information and the axon which sends information to other neurons / muscles/glands.

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4
Q

Axon

A

This is a long projection known as a nerve fibre which transmits information in the form of an electrical impulse to another neuron / muscle / gland.

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5
Q

Identify the myelin sheath on a neuron and state its function

A

Axons are surrounded by a myelin sheath. The myelin sheath insulates the axon and increases the speed of transmission / conduction of an electrical impulse.

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6
Q

Identify the cells that support neurons and produce the myelin sheath.

A

Glial cells support neurons and produce the myelin sheath – sleeves of fatty tissue that are wrapped around the axon.

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7
Q

Describe the process of myelination during maturation.

A

Myelination is a process that occurs from birth to adolescence leading to the creation of myelin sheaths around the axons of neurons. This myelination develops over time allowing the nerve impulses to be conducted more rapidly and leading to increasing co-ordination and more rapid responses to stimuli during the first two years of life.

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8
Q

Explain the impact of a disease which destroys the myelin sheath.

A

Diseases that attack and destroy the myelin sheath reduce the ability of neurons to conduct electrical impulses leading to a loss of co-ordination e.g. multiple sclerosis

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9
Q

Describe the transmission of an electrical impulse across a synapse. (1)

A

Neurons are connected to other neurons / muscle / glands by synaptic clefts.

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10
Q

Describe the transmission of an electrical impulse across a synapse (2)

A

A synaptic cleft is a physical gap across which neurotransmitters will diffuse to relay an electrical impulse across the synaptic cleft.

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11
Q

Describe the transmission of an electrical impulse across a synapse (3)

A

When an electrical impulse travels through the pre-synaptic neuron and reaches the axon ending, this triggers the release of neurotransmitters which are stored in vesicles.

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12
Q

Describe the transmission of an electrical impulse across a synapse (4)

A

The neurotransmitters are released into the synaptic cleft and diffuse across the gap where they bind to receptors in the post-synaptic neuron

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13
Q

Describe the transmission of an electrical impulse across a synapse (5)

A

When enough neurotransmitter molecules have bound to receptors, this triggers an electrical impulse in the post-synaptic membrane or causes a muscle contraction or a gland secretion.

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14
Q

Explain what is meant by the term ‘threshold level’

A

A minimum number of neurotransmitter molecules must attach to the receptors in the post-synaptic membrane in order to trigger an impulse to fire in the post-synaptic neuron. This minimum number of neurotransmitter molecules is referred to as the threshold level.

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15
Q

State what is meant by ‘summation’.

A

Summation is the term used to describe the adding together of weak stimuli either from multiple presynaptic neurons or from a series of stimuli in order to reach the threshold level required to trigger a nerve impulse to fire in the postsynaptic neuron. Summation occurs in a converging neural pathway such as the rods of the retina in dim light.

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16
Q

State the two ways that neurotransmitters are removed from a synaptic cleft.

A

Neurotransmitters are removed from a synaptic cleft either by :

· enzyme breakdown

e.g. acetylcholine is broken down by acetylcholinesterase

or

· through reuptake (reabsorption) by the presynaptic neuron

e.g. noradrenaline / norepinephrine

17
Q

Explain the need for removal of neurotransmitters from a synapse.

A

Neurotransmitters must be removed from the synapse to prevent continuous stimulation of postsynaptic neurons.

18
Q

State the role of receptors in determining the outcome of a nerve impulse.

A

The receptors in the post-synaptic membrane determine whether the signal is excitatory or inhibitory e.g. acetylcholine release can be excitatory (promoting an impulse) or inhibitory (stopping an impulse) depending upon the type of receptor on the post-synaptic membrane.

19
Q

State the role of receptors in determining the outcome of a nerve impulse. (2)

A

Synapses can also filter out weak stimuli arising from insufficient secretion of neurotransmitters when the threshold level is not reached.