3.4 Mass Transport in Animals Flashcards
What is mass transport?
Mass transport is the bulk movement of gases or liquids in one direction at a constant speed, usually via a system of vessels and tubes.
What is the function of haemoglobin?
Haemoglobin is responsible for binding oxygen in the lungs and transporting the oxygen to the tissue to be used in aerobic metabolic pathways.
Describe cooperative binding.
The binding of the first oxygen molecule results in a conformational change in the structure of the haemoglobin molecule, making it easier for each successive oxygen molecule to bind (increasing its affinity for oxygen). → uncovers the haem group making it more available for successive O2 to bind to
What does the oxygen dissociation curve show?
The rate at which oxygen associates, and also dissociates, with haemoglobin at different partial pressures of oxygen.
- low saturation (start of graph) = respiring cells
- high saturation (end of graph)= alveoli
What is partial pressure?
The pressure exerted by an individual gas in a mixture- in this case the concentration of oxygen
When is haemoglobin considered to be “saturated”?
When all four haem groups have bound to an oxygen molecule.
What is the ease at which haemoglobin binds to and dissociates with oxygen called?
Affinity for oxygen
Desctibe a low affinity for oxygen
binds to O2 less easily but release more easily
Describe a high affinity for oxygen?
- binds easily to oxygen but **release less easily **
What is meant by unloading?
haemoglobin releases O2 into the tissues (low affinity)
What is meant by loading?
haemoglobin binds with O2 in lungs (high affinity)
Why is the dissociation curve S-shaped?
Due to cooperative binding.
What is the Bohr effect?
Changes in the oxygen dissociation curve as a result of carbon dioxide levels.
What happens when the partial pressure of carbon dioxide in the blood is high?
Haemoglobin’s affinity for oxygen is reduced by decreasing blood pH resulting in a conformational shape change therefore oxygen is given up more readily (increased dissociation/decreased O2 affinity).
How does an increase in partial pressure of carbon dioxide affect the graph?
Graph shifts to the right.