3363 meds Flashcards

1
Q

MAOI antidepressant examples

A

Nardil and Parnate

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2
Q

when are MAOI used

A

when all else has failed
cant be given w other antidepressants

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3
Q

MAOI adverse effects

A

insomnia, nausea, agitation, confusion, hypotension, weight gain , sexual impotence, constipation

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4
Q

MAOI diet

A

cant have tyramine
ex: aged cheese, wine, smoked meats, fava beans, saurkraut, avocado

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5
Q

hypertensive crisis

A

MAO inhibitor and tyramine is not metabolized, increased norepinephrine, vasoconstriction and increased HR

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6
Q

hypertensive crisis s/s

A

occipital headache
stiff neck
flushing
palpitations
diaphoresis
nausea
fever

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7
Q

antidote for hypertensive crisis

A

Ca channel blockers

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8
Q

tricyclic MOA

A

inhibit reuptake of norepinepherine and serotonin

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9
Q

tricyclic examples

A

Elavil, Anafranil, Aventyl

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10
Q

tricyclics are lethal in OD

A

yes

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11
Q

side effects of tricyclics

A

anticholiergic, postural hypotension, constipation and urinary retention

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12
Q

when should you take tricyclics

A

night

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13
Q

how long does it take tricyclics to work

A

2 months

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14
Q

SSRI : 5-HT2 receptors MOA

A

blocks reuptake of serotonin

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15
Q

SSRI examples

A

celexa, cipralex, prozac, luvox, paxil, zoloft

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16
Q

first line treatment in depression

A

SSRIs

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17
Q

which antidepressant is also used for anxiety

A

SSRIs

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18
Q

side effects SSRI

A

insomnia, low libido, nausea, vomiting, arrhythmias in lower doses

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19
Q

serotonin syndrome causes

A

caused by too high of a dose or concurrent use with MAOI

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20
Q

serotonin syndrome s/s

A

restless, tachycardia, fever, high BP, altered mental status, hostile, muscle rigidity, stomach ache, diarrhea

F- flu like
L- light headed
U- uneasiness
S- sleep and sensory disturbance
H- headache

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21
Q

what to do in serotonin syndrome

A

hold SSRI
call doc (anticipate serotonin receptor blocker)
cooling blanket
valium for rigidity
anticonvulsant
artificial ventilation

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22
Q

SNRI example

A

effexor and cymbalta

23
Q

side effects SNRI

A

hypertension, insomnia, sweating, agitation

24
Q

SNRI used for

A

major depression

25
Mood stabilizer drug
lithium
26
lithium side effects
polyuria. encourage normal salt intake as too low with increase toxicity mild tremors.
27
toxic lithium signs
dehydration, atxia
28
anticonvulsant/ mood stabilizers
decrease GABA epival and depakene and carbamazepine and lamotrigine
29
normal lithium levels
0.4-1
30
1st gen antipsychotics MOA
prevent dopamine from activating dopamine receptors: decrease circulating dopamine
31
examples of 1st gen atipsychotics
thorazine, haldol, stelazine, clopixol acuphase -xol, -dol, -zine
32
clopixol acuphase
for emergent situations. sedate and settles for 72 hours
33
side effects of 1st gen antipsychotics
EPS, tardive dyskinesia, stiff fat, low BP, sedated, cant ejaculate , drooling
34
EPS
- acute dystonia (sustained contraction in muscles) - akathisia (restless) -pseudoparkinsonism (tremor, shuffling gait)
35
treatment of dystonia
IM cogention or IM benadryl
36
treatment of akathesia and pseudoparkinsonism
antiparkinson/anticholinergic
37
clozaril
check for WBC weekly for first 6 months for risk of agranulocytosis. last resort for 2nd gen atypical antipsychotics
38
first line atypical antipsychotics
-done and -pine
39
excessive drooling happens in which antipsychotic
alpha 2 adrenergic
40
olanzapine increases risk of
metabolic syndrome. hyperglycemia with type II diabetes,
41
risperidone
- low risk of agranulosytosis but increased risk for sexual dysfunction - most sedating
42
quetiapine
monitor for OH
43
weight gain is more common in
2nd gen antipsychotics
44
3rd gen
dopamine stabilizer
45
3rd gen examples
abilify, cariprazine, brexpiprazole
46
abilify main side effects
akathesia and insomnia
47
which meds do not cause weight gain
abilify and zeldox
48
neuroleptic malignant syndrome (NMS)
occurs with 1,2,3 gen acute reduction of doapmine decreased LOC, muscle ridigd, fever, drooling, changes in breathing
49
what to do with NMS
bromocriptine for muscle rigdity
50
anti-anxiety meds
benzos. end in -pam
51
withdrawl from benzos (sedatives)
3-4 months insomnia, irritable, nervous, dry mouth, confusion
52
busprione
non-benzo antianxiety, minimal sedation, takes awhile to work, used with ativan
53
goal with taking anti-anxiety meds
short term use