3363 meds Flashcards
MAOI antidepressant examples
Nardil and Parnate
when are MAOI used
when all else has failed
cant be given w other antidepressants
MAOI adverse effects
insomnia, nausea, agitation, confusion, hypotension, weight gain , sexual impotence, constipation
MAOI diet
cant have tyramine
ex: aged cheese, wine, smoked meats, fava beans, saurkraut, avocado
hypertensive crisis
MAO inhibitor and tyramine is not metabolized, increased norepinephrine, vasoconstriction and increased HR
hypertensive crisis s/s
occipital headache
stiff neck
flushing
palpitations
diaphoresis
nausea
fever
antidote for hypertensive crisis
Ca channel blockers
tricyclic MOA
inhibit reuptake of norepinepherine and serotonin
tricyclic examples
Elavil, Anafranil, Aventyl
tricyclics are lethal in OD
yes
side effects of tricyclics
anticholiergic, postural hypotension, constipation and urinary retention
when should you take tricyclics
night
how long does it take tricyclics to work
2 months
SSRI : 5-HT2 receptors MOA
blocks reuptake of serotonin
SSRI examples
celexa, cipralex, prozac, luvox, paxil, zoloft
first line treatment in depression
SSRIs
which antidepressant is also used for anxiety
SSRIs
side effects SSRI
insomnia, low libido, nausea, vomiting, arrhythmias in lower doses
serotonin syndrome causes
caused by too high of a dose or concurrent use with MAOI
serotonin syndrome s/s
restless, tachycardia, fever, high BP, altered mental status, hostile, muscle rigidity, stomach ache, diarrhea
F- flu like
L- light headed
U- uneasiness
S- sleep and sensory disturbance
H- headache
what to do in serotonin syndrome
hold SSRI
call doc (anticipate serotonin receptor blocker)
cooling blanket
valium for rigidity
anticonvulsant
artificial ventilation
SNRI example
effexor and cymbalta
side effects SNRI
hypertension, insomnia, sweating, agitation
SNRI used for
major depression